[1]
|
Siegel, R., Ma, J. and Zou, Z. (2014) Cancer Statistics, 2014. CA: A Cancer Journal for Clinicians, 64, 9-29.
https://doi.org/10.3322/caac.21208
|
[2]
|
Solito, S., Marigo, I., Pinton, L., et al. (2014) Myeloid-Derived Suppressor Cell Heterogeneity in Human Cancers. Annals of the New York Academy of Sciences, 1319, 47-65. https://doi.org/10.1111/nyas.12469
|
[3]
|
Gabrilovich, D.I. and Nagaraj, S. (2009) Myeloid-Derived Suppressor Cells as Regulators of the Immune System. Nature Reviews Immunology, 9, 162-174. https://doi.org/10.1038/nri2506
|
[4]
|
刘秋燕, 曹雪涛. MDSCs与肿瘤免疫逃逸[J]. 中国肿瘤生物治疗杂志, 2009, 16(4): 319-324.
|
[5]
|
Kusmartsev, S., Su, Z., Heiser, A., et al. (2008) Reversal of Myeloid Cell-Mediated Immunosuppression in Patients with Metastatic Renal Cell Carcinoma. Clinical Cancer Research, 14, 8270-8278.
https://doi.org/10.1158/1078-0432.CCR-08-0165
|
[6]
|
Pak, A.S., Wright, M.A., Matthews, J.P., et al. (1995) Mechanisms of Immune Suppression in Patients with Head and Neck Cancer: Presence of CD34(+) Cells Which Suppress Immune Functions within Cancers That Secrete Granulocytemacrophage Colony-Stimulating Factor. Clinical Cancer Research, 1, 95-103.
|
[7]
|
Dolcetti, L., Marigo, I., Mantelli, B., et al. (2008) Myeloid-Derived Suppressor Cell Role in Tumor-Relatied Inflammation. Cancer Letters, 267, 216-225. https://doi.org/10.1016/j.canlet.2008.03.012
|
[8]
|
Mabel, D. and Gabrilovich, D.I. (2015) Myeloid-Derived Suppressor Cells in the Tumor Microenvironment:Expect the Unexpected. Journal of Clinical Investigation, 125, 3356-3364. https://doi.org/10.1172/JCI80005
|
[9]
|
Damuzzo, V., Pinton, L., Desantis, G., et al. (2015) Complexity and Challenges in Defining Myeloid-Derived Suppressor Cells. Cytometry B Clinical Cytometry, 88, 77-91.
|
[10]
|
Noman, M.Z., Desantis, G., Janji, B., et al. (2014) PD-L1 Is a Novel Direct Target of HIF-1, and Its Blockade under Hypoxia Enhanced MDSC-Mediated T Cell Activation. Journal of Experimental Medicine, 211, 781-790.
https://doi.org/10.1084/jem.20131916
|
[11]
|
Zhong, H., Gutkin, D.W., Han, B., et al. (2014) Origin and Pharmacological Modulation of Tumor-Associated Regulatory Dendritic Cells. International Journal of Cancer, 134, 2633-2645. https://doi.org/10.1002/ijc.28590
|
[12]
|
Wu, L., Du, H., Li, Y., et a1. (2011) Signal Transducer and Activator of Transcription 3(Stat3C) Promotes Myeloid-Derived Suppressor Cell Expansion and Immune Suppression during Lung Tumorigenesis. American Journal of Pathology, 179, 2131-2141. https://doi.org/10.1016/j.ajpath.2011.06.028
|
[13]
|
Ko, J.S., Bukowski, R.M. and Fincke, J.H. (2009) Myeloid-Derived Suppressor Cells: A Novel Therapeutic Target. Current Oncology Reports, 11, 87-93. https://doi.org/10.1007/s11912-009-0014-6
|
[14]
|
Huang, B., Pan, P.Y., Li, Q., et al. (2006) Gr-1 + CD115 + Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Cell Anergy in Tumor-Bearing Host. Cancer Research, 66, 1123-1131.
https://doi.org/10.1158/0008-5472.CAN-05-1299
|
[15]
|
Pages, F., Berger, A., Camus, M., et al. (2005) Effector Memory T Cells, Early Metastasis, and Survival in Colorectal Cancer. New England Journal of Medicine, 353, 2654-2666. https://doi.org/10.1056/NEJMoa051424
|
[16]
|
Yang, L., DeBusk, L.M., Fukuda, K., et al. (2004) Expansion of Myeloid Immune Suppressor Gr+ CD11b+ Cells in Tumor-Bearing Host Directly Promotes Tumor Angiogenesis. Cancer Cell, 6, 409-421.
https://doi.org/10.1016/j.ccr.2004.08.031
|
[17]
|
Cross, S.S., Hamdy, F.C., Deloulme, J.C., et al. (2005) Expression of S100 Proteins in Normal Human Tissues and Common Cancers Using Tissue Microarrays: S100A6, S100A8, S100A9 and S100A11 Are All Overexpressed in Common Cancers. Histopathology, 46, 256-269. https://doi.org/10.1111/j.1365-2559.2005.02097.x
|
[18]
|
Connolly, M.K., Mallen-St Clair, J., Bedrosian, A.S., et al. (2010) Distinct Populations of Metastases-Enabling Myeloid Cells Expand in the Liver of Mice Harboring Invasive and Preinvasive Intra-Abdominal Tumor. Journal of Leukocyte Biology, 87, 713-725. https://doi.org/10.1189/jlb.0909607
|
[19]
|
Walker, M.R., Kasprowicz, D.J., Gersuk, V.H., et al. (2003) Induction of FoxP3 and Acquisition of T Regulatory Activity by Stimulated Human CD4+ CD25+ T Cells. Journal of Clinical Investigation, 112, 1437-1443.
https://doi.org/10.1172/JCI19441
|
[20]
|
Hori, S., Nomura, T. and Sakaguchi, S. (2003) Control of Regulatory T Cell Development by the Transcription Factor FOXP3. Science, 299, 1057-1061.
|
[21]
|
Fontenot, J.D., Gavin, M.A. and Rudensky, A.Y. (2003) FOXP3 Programs the Development and Function of CD4+ CD25+ Regulatory T Cells. Nature Immunology, 4, 330-336. https://doi.org/10.1038/ni904
|
[22]
|
Khattri, R., Cox, T., Yasayko, S.A., et al. (2003) An Essential Role for Scurfin in CD4+ CD25+ T Regulatory Cells. Nature Immunology, 4, 337-342. https://doi.org/10.1038/ni909
|
[23]
|
Gregori, S., Passerini, L. and Roncarolo, M.G. (2015) Clinical Outlook for Type-1 and Foxp3+ T Regulatory Cell-Based Therapy. Frontiers in Immunology, 6, 593. https://doi.org/10.3389/fimmu.2015.00593
|
[24]
|
Centuori, S.M., Trad, M., LaCasse, C.J., et al. (2012) Myeloid-Derived Suppressor Cells from Tumor-Bearing Mice Impair TGF-Beta-Induced Differentiation of CD4+ CD25+ FoxP3+ Tregs from CD4+ CD25-FoxP3-T Cells. Journal of Leukocyte Biology, 92, 987-997. https://doi.org/10.1189/jlb.0911465
|
[25]
|
Ji, J., Xu, J., Zhao, S., et al. (2016) Myeloid-Derived Suppressor Cells Contribute to Systemic Lupus Erythematosus by Regulating Differentiation of Th17 Cells and Treg. Clinical Science, 130, 1453-1467.
https://doi.org/10.1042/CS20160311
|
[26]
|
O’Connor, M.A., Vella, J.L. and Green, W.R. (2016) Reciprocal Relationship of T Regulatory Cells and Monocytic Myeloid-Derived Suppressor Cells in LP-BM5 Murine Retrovirus-Induced Immunodeficiency. Journal of General Virology, 97, 509-522. https://doi.org/10.1099/jgv.0.000260
|
[27]
|
Jayaraman, P., Alfarano, M.G., Svider, P.F., et al. (2014) iNOS Expression in CD4+ T Cells Limits Treg Induction by Repressing TGFβ1: Combined iNOS Inhibition and Treg Depletion Unmask Endogenous Antitumor Immunity. Clinical Cancer Research, 20, 6439-6451. https://doi.org/10.1158/1078-0432.CCR-13-3409
|
[28]
|
Ren, J.P., Zhao, J., Dai, J., et al. (2016) Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Regulate T Cell Differentiation and Function via the STAT3 Pathway. Immunology, 148, 377-386. https://doi.org/10.1111/imm.12616
|
[29]
|
Wang, L., Zhao, J., Ren, J.P., et al. (2016) Expansion of Myeloid-Derived Suppressor Cells Promotes Differentiation of Regulatory T Cells in HIV-1+ Individuals. AIDS, 30, 1521-1531. https://doi.org/10.1097/QAD.0000000000001083
|
[30]
|
Zahorchak, A.F., Ezzelarab, M.B., Lu, L., et al. (2016) In Vivo Mobilization and Functional Characterization of Nonhuman Primate Monocytic Myeloid-Derived Suppressor Cells. American Journal of Transplantation, 16, 661-671.
https://doi.org/10.1111/ajt.13454
|
[31]
|
Luan, Y., Mosheir, E., Menon, M.C., et al. (2013) Monocytic Myeloid-Derived Suppressor Cells Accumulate in Renal Transplant Patients and Mediate CD4+ Foxp3+ Treg Expansion. American Journal of Transplantation, 13, 3123-3131.
https://doi.org/10.1111/ajt.12461
|
[32]
|
Wang, W., Jiao, Z., Duan, T., et al. (2015) Functional Characterization of Myeloid-Derived Suppressor Cell Subpopulations during the Development of Experimental Arthritis. European Journal of Immunology, 45, 464-473.
https://doi.org/10.1002/eji.201444799
|
[33]
|
沈彦伟, 高旭霞, 李晶晶, 等. 肿瘤患者化疗前后外周血NK/T及Treg细胞比例分析[J]. 中华结直肠疾病电子杂志, 2012, 1(1): 25-27.
|
[34]
|
高素珍, 韩慧霞. CD4+ CD25+调节性T细胞在结直肠癌中的表达及其意义[J]. 中国癌症杂志, 2008, 18(4): 245-248.
|
[35]
|
Pachmann, K., Clement, J.H., Schneider, C.P., et al. (2005) Standardized Quantification of Circulating Peripheral Tumor Cells from Lung and Breast Cancer. Clinical Chemistry and Laboratory Medicine, 43, 6l7-627.
|
[36]
|
Gilbey, A.M., Burnett, D., Coleman, R.E., et al. (2004) The Detection of Circulating Breast Cancer Cells in Blood. Journal of Clinical Pathology, 57, 903-911. https://doi.org/10.1136/jcp.2003.013755
|
[37]
|
Smith, H.A. and Kang, Y. (2013) The Metastasis-Promoting Roles of Tumor-Associated Immune Cells. Journal of Molecular Medicine, 91, 411-429. https://doi.org/10.1007/s00109-013-1021-5
|
[38]
|
Nishikawa, H. and Sakaguchi, S. (2010) Regulatory T Cells in Tumor Immunity. International Journal of Cancer, 127, 759-767. https://doi.org/10.1002/ijc.25429
|
[39]
|
Sica, A., Larghi, P., Mancino, A., et al. (2008) Macrophage Polarization in Tumour Progression. Seminars in Cancer Biology, 18, 349-355. https://doi.org/10.1016/j.semcancer.2008.03.004
|
[40]
|
Shurin, M.R., Naiditch, H., Zhong, H., et al. (2011) Regulatory Dendritic Cells: New Targets for Cancer Immunotherapy. Cancer Biology & Therapy, 11, 988-992. https://doi.org/10.4161/cbt.11.11.15543
|
[41]
|
Gabrilovich, D.I., Ostrand-Rosenberg, S. and Bronte, V. (2012) Coordinated Regulation of Myeloid Cells by Tumours. Nature Reviews Immunology, 12, 253-268. https://doi.org/10.1038/nri3175
|
[42]
|
Choi, J., Suh, B., Ahn, Y.O., et al. (2012) CD15+/CD16low Human Granulocytes from Terminal Cancer Patients: Granulocytic Myeloid-Derived Suppressor Cells That Have Suppressive Function. Tumor Biology, 33, 121-129.
https://doi.org/10.1007/s13277-011-0254-6
|
[43]
|
Li, H., Han, Y., Guo, Q., et al. (2009) Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Energy of NK Cells through Membrane-Bound TGF-beta1. The Journal of Immunology, 182, 240-249.
https://doi.org/10.4049/jimmunol.182.1.240
|
[44]
|
Talmadge, J.E. and Gabrilovich, D.I. (2013) History of Myeloid-Derived Suppressor Cells. Nature Reviews Cancer, 13, 739-752. https://doi.org/10.1038/nrc3581
|
[45]
|
Ostrand-Rosenberg, S., Sinha, P., Beury, D.W., et al. (2012) Cross-Talk between Myeloid-Derived Suppressor Cells (MDSC), Macrophages, and Dendritic Cells Enhances Tumor-Induced Immune Suppression. Seminars in Cancer Biology, 22, 275-281. https://doi.org/10.1016/j.semcancer.2012.01.011
|
[46]
|
Creighton, C.J., Chang, J.C. and Rosen, J.M. (2010) Epithelial-Mesenchymal Transition (EMT) in Tumor-Initiating Cells and Its Clinical Implications in Breast Cancer. Journal of Mammary Gland Biology and Neoplasia, 15, 253-260.
https://doi.org/10.1007/s10911-010-9173-1
|
[47]
|
Toh, B., Wang, X., Keeble, J., et al. (2011) Mesenchymal Transition and Dissemination of Cancer Cells Is Driven by Myeloid-Derived Suppressor Cells Infiltrating the Primary Tumor. PLOS Biology, 9, e1001162.
https://doi.org/10.1371/journal.pbio.1001162
|
[48]
|
Guedez, L., Jensen Taubman, S., Bourboulia, D., et al. (2012) TIMP-2 Targets Tumor-Associated Myeloid Suppressor Cells with Effects in Cancer Immune Dysfunction and Angiogenesis. Journal of Immunotherapy, 35, 502-512.
https://doi.org/10.1097/CJI.0b013e3182619c8e
|
[49]
|
Kumar, V., Patel, S., Tcyganov, E., et al. (2016) The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment. Trends in Immunology, 37, 208-220. https://doi.org/10.1016/j.it.2016.01.004
|
[50]
|
Panni, R.Z., Sanford, D.E., Belt, B.A., et al. (2014) Tumor-Induced STAT3 Activation in Onocytic Myeloid-Derived Suppressor Cells Enhances Stemness and Mesenchymal Properties in Human Pancreatic Cancer. Cancer Immunology, Immunotherapy, 63, 513-528. https://doi.org/10.1007/s00262-014-1527-x
|
[51]
|
Qian, B.Z., Li, J., Zhang, H., et al. (2011) CCL2 Recruits Inflammatory Monocytes to Facilitate Breast-Tumour Metastasis. Nature, 475, 222-225. https://doi.org/10.1038/nature10138
|
[52]
|
Zhao, X., Rong, L., Zhao, X., et al. (2012) TNF Signaling Drives Myeloid-Derived Suppressor Cell Accumulation. Journal of Clinical Investigation, 122, 4094-4104. https://doi.org/10.1172/JCI64115
|
[53]
|
Corzo, C.A., Condamine, T., Lu, L., et al. (2010) HIF-1α Regulates Function and Differentiation of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment. The Journal of Experimental Medicine, 207, 2439-2453.
https://doi.org/10.1084/jem.20100587
|
[54]
|
Haile, L.A., Greten, T.F. and Korangy, F. (2012) Immune Suppression: The Hallmark of Myeloid Derived Suppressor Cells. Immunological Investigations, 41, 581-594. https://doi.org/10.3109/08820139.2012.680635
|
[55]
|
Bates, R.C., Pursell, B.M. and Mercurio, A.M. (2007) Epithelial-Mesenchymal Transition and Colorectal Cancer: Gaining Insights into Tumor Progression Using LIM 1863 Cells. Cells Tissues Organs, 185, 29-39.
|
[56]
|
Hayward, I.P., Whitehead, R.H., Ward, L., et al. (1995) Effect of TGF-β on Differentiated Organoids of the Colon Carcinoma Cell Line LIM 1863. Immunology & Cell Biology, 73, 249-257. https://doi.org/10.1038/icb.1995.41
|
[57]
|
Bates, R.C. and Mercurio, A.M. (2003) Tumor Necrosis Factor-Alpha Stimulates the Epithelial-to-Mesenchymal Transition of Human Colonic Organoids. Molecular Biology of the Cell, 14, 1790-1800.
https://doi.org/10.1091/mbc.e02-09-0583
|