[1]
|
Madrazo, E., Conde, A.C. and Redondo-Munoz, J. (2017) Inside the Cell: Integrins as New Governors of Nuclear Alterations? Can-cers, 9, 82. https://doi.org/10.3390/cancers9070082
|
[2]
|
Schips, T.G., Vanhoutte, D., Vo, A., et al. (2019) Thrombospondin-3 Augments Injury-Induced Cardiomyopathy by Intracellular Integrin Inhibition and Sarcolemmal Instability. Nature Communications, 10, 76.
https://doi.org/10.1038/s41467-018-08026-8
|
[3]
|
Niu, J. and Li, Z. (2017) The Roles of Integrin Alphavbeta6 in Cancer. Cancer Letters, 403, 128-137.
https://doi.org/10.1016/j.canlet.2017.06.012
|
[4]
|
Xiong, J.P., Stehle, T., Diefenbach, B., et al. (2001) Crystal Structure of the Extracellular Segment of Integrin Alpha Vbeta3. Science, 294, 339-345. https://doi.org/10.1126/science.1064535
|
[5]
|
Holtke, C. (2018) isoDGR-Peptides for Integrin Targeting: Is the Time Up for RGD? Journal of Medicinal Chemistry, 61, 7471-7473. https://doi.org/10.1021/acs.jmedchem.8b01123
|
[6]
|
Guo, J., Zhang, Y., Li, H., et al. (2018) Intramembrane Ionic Protein-Lipid Interaction Regulates Integrin Structure and Function. PLoS Biology, 16, e2006525. https://doi.org/10.1371/journal.pbio.2006525
|
[7]
|
Zoppi, N., Chiarelli, N., Ritelli, M., et al. (2018) Multifaced Roles of the αvβ3 Integrin in Ehlers-Danlos and Arterial Tortuosity Syndromes’ Dermal Fibroblasts. International Journal of Molecular Sciences, 19, pii: E982.
https://doi.org/10.3390/ijms19040982
|
[8]
|
Sun, C.C., Qu, X.J. and Gao, Z.H. (2016) Arginine-Glycine-Aspartate-Binding Integ-rins as Therapeutic and Diagnostic Targets. American Journal of Therapeutics, 23, e198-e207. https://doi.org/10.1097/MJT.0000000000000053
|
[9]
|
Streuli, C.H. and Akhtar, N. (2009) Signal Co-Operation between Integ-rins and Other Receptor Systems. The Biochemical Journal, 418, 491-506. https://doi.org/10.1042/BJ20081948
|
[10]
|
Temming, K., Schiffelers, R.M., Molema, G., et al. (2005) RGD-Based Strategies for Selective Delivery of Therapeutics and Imaging Agents to the Tumour Vasculature. Drug Resistance Updates: Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy, 8, 381-402. https://doi.org/10.1016/j.drup.2005.10.002
|
[11]
|
Hsieh, M.T., Wang, L.M., Changou, C.A., et al. (2017) Crosstalk be-tween Integrin αvβ3 and ERalpha Contributes to Thyroid Hormone-Induced Proliferation of Ovarian Cancer Cells. Oncotarget, 8, 24237-24249.
https://doi.org/10.18632/oncotarget.10757
|
[12]
|
Cheresh, D.A. and Stupack, D.G. (2002) Integrin-Mediated Death: An Explana-tion of the Integrin-Knockout Phenotype? Nature Medicine, 8, 193-194. https://doi.org/10.1038/nm0302-193
|
[13]
|
Aoudjit, F. and Vuori, K. (2001) Matrix Attachment Regulates Fas-Induced Apoptosis in Endothelial Cells: A Role for c-Flip and Implications for Anoikis. The Journal of Cell Biology, 152, 633-643. https://doi.org/10.1083/jcb.152.3.633
|
[14]
|
Fidler, I.J. (2003) The Pathogen-esis of Cancer Metastasis: The “Seed and Soil” Hypothesis Revisited. Nature Reviews Cancer, 3, 453-458. https://doi.org/10.1038/nrc1098
|
[15]
|
Van Der Pluijm, G., Sijmons, B., Vloedgraven, H., et al. (2001) Uroki-nase-Receptor/Integrin Complexes Are Functionally Involved in Adhesion and Progression of Human Breast Cancer in Vivo. The American Journal of Pathology, 159, 971-982. https://doi.org/10.1016/S0002-9440(10)61773-7
|
[16]
|
Kubas, H., Schafer, M., Bauder-Wust, U., et al. (2010) Multivalent Cyclic RGD Ligands: Influence of Linker Lengths on Receptor Binding. Nuclear Medicine and Biology, 37, 885-891. https://doi.org/10.1016/j.nucmedbio.2010.06.005
|
[17]
|
Desgrosellier, J.S. and Cheresh, D.A. (2010) Integrins in Cancer: Biological Implications and Therapeutic Opportunities. Nature Reviews Cancer, 10, 9-22. https://doi.org/10.1038/nrc2748
|
[18]
|
Beer, A.J. and Schwaiger, M. (2011) PET Imaging of αvβ3 Expression in Cancer Patients. Methods in Molecular Biology, 680, 183-200. https://doi.org/10.1007/978-1-60761-901-7_13
|
[19]
|
Chen, Z., Fu, F., Li, F., et al. (2018) Comparison of [(99m)Tc]3PRGD2 Imaging and [(18)F]FDG PET/CT in Breast Cancer and Expression of Integrin αvβ3 in Breast Cancer Vascular Endothelial Cells. Molecular Imaging and Biology, 20, 846-856. https://doi.org/10.1007/s11307-018-1178-y
|
[20]
|
Lv, N., Gao, S., Bai, L., et al. (2019) Advantages of (99m)Tc-3PRGD2 SPECT over CT in the Preoperative Assessment of Lymph Node Metastasis in Patients with Esophageal Cancer. Annals of Nuclear Medicine, 33, 39-46.
https://doi.org/10.1007/s12149-018-1300-x
|
[21]
|
O’connor, J.P., Jackson, A., Parker, G.J., et al. (2007) DCE-MRI Biomarkers in the Clinical Evaluation of Antiangiogenic and Vascular Disrupting Agents. British Journal of Cancer, 96, 189-195. https://doi.org/10.1038/sj.bjc.6603515
|
[22]
|
Hersey, P., Sosman, J., O’day, S., et al. (2010) A Randomized Phase 2 Study of Etaracizumab, a Monoclonal Antibody against Integrin alpha(v)beta(3), + or − Dacarbazine in Patients with Stage IV Metastatic Mela-noma. Cancer, 116, 1526-1534. https://doi.org/10.1002/cncr.24821
|
[23]
|
Borst, A.J., James, Z.M., Zagotta, W.N., et al. (2017) The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human αvβ3 Integrin via Steric Hindrance. Structure, 25, 1732-9.e5.
https://doi.org/10.1016/j.str.2017.09.007
|
[24]
|
Gutheil, J.C., Campbell, T.N., Pierce, P.R., et al. (2000) Targeted Antiangiogenic Therapy for Cancer Using Vitaxin: A Humanized Monoclonal Antibody to the Integrin αvβ3. Clinical Cancer Research, 6, 3056-3061.
|
[25]
|
Trikha, M., Zhou, Z., Timar, J., et al. (2002) Multiple Roles for Platelet GPIIb/IIIa and αvβ3 Integrins in Tumor Growth, Angiogenesis, and Metastasis. Cancer Research, 62, 2824-2833.
|
[26]
|
Sheldrake, H.M. and Patterson, L.H. (2009) Function and Antagonism of beta3 Integrins in the Development of Cancer Therapy. Current Cancer Drug Targets, 9, 519-540. https://doi.org/10.2174/156800909788486713
|
[27]
|
Xiong, J.P., Stehle, T., Zhang, R., et al. (2002) Crystal Structure of the Ex-tracellular Segment of Integrin Alpha Vbeta3 in Complex with an Arg-Gly-Asp Ligand. Science, 296, 151-155. https://doi.org/10.1126/science.1069040
|
[28]
|
Zhang, L., Gulses, A., Purcz, N., et al. (2019) A Comparative Assessment of the Effects of Integrin Inhibitor Cilengitide on Primary Culture of Head and Neck Squamous Cell Carcinoma (HNSCC) and HNSCC Cell Lines. Clinical & Translational Oncology. https://doi.org/10.1007/s12094-018-02025-3
|
[29]
|
Kumar, C.C., Malkowski, M., Yin, Z., et al. (2001) Inhibition of Angiogenesis and Tumor Growth by SCH221153, a Dual alpha(v)beta3 and alpha(v)beta5 Integrin Re-ceptor Antagonist. Cancer Research, 61, 2232-2238.
|
[30]
|
Chu, J.J. and Ng, M.L. (2004) Interaction of West Nile Virus with αvβ3 Integrin Mediates Virus Entry into Cells. The Journal of Biological Chemistry, 279, 54533-54541. https://doi.org/10.1074/jbc.M410208200
|
[31]
|
Hsu, A.R., Veeravagu, A., Cai, W., et al. (2007) Integrin αvβ3 Antagonists for Anti-Angiogenic Cancer Treatment. Recent Patents on Anti-Cancer Drug Discovery, 2, 143-158. https://doi.org/10.2174/157489207780832469
|