弧形导管插入电子支气管镜诊疗不明原因胸腔积液的研究
Research of the Diagnosis andTreatment of Unexplained Pleural Effusion with Curved Bronchoscopy and Electronic Bronchoscopy
DOI: 10.12677/ACM.2020.103046, PDF,   
作者: 张永辉:南昌大学第二附属合作铅山人民医院呼吸内科,江西 南昌;历风元:南昌大学附属第三医院呼吸内科,江西 南昌
关键词: 弧形穿刺管电子支气管镜胸腔积液Curved Puncture Tube Electronic Bronchoscope Pleural Effusion
摘要: 目的:探讨通过弧形导管插入电子支气管镜代替内科胸腔镜诊疗不明原因胸腔积液的临床效果。方法:选52例呼吸内科2018年1月~2020年2月收治的不明原因胸腔积液患者。随机分成研究组和对照组。研究组应用弧形导管插入电子支气管镜检查及诊断;对照组只应用电子支气管镜进行检查及诊断。分析两组病患的胸腔积液的确诊率、手术时间、病理组织结果以及手术并发症情况。结果:研究组确诊率高于对照组(25/26~19/26,确诊率96%~73%),差异具有统计学意义(P < 0.05)。不明原因胸腔积液病理诊断最多的为结核性胸膜炎,其次为恶性肿瘤。两组手术时间对比,研究组手术时间38.15 ± 7.5分钟;对照组手术时间52.23 ± 8.2分钟。两组差异具有统计学意义(P < 0.05)。两组并发症发生率比较无统计学意义。结论:通过弧形导管插入电子支气管镜诊疗不明原因胸腔积液的诊断率更高、手术时间更短。疗效好,值得临床推广使用。
Abstract: Objective: To explore the clinical effect of the diagnosis and treatment of pleural effusion of un-known cause by using electronic bronchoscope instead of medical thoracoscopy through arc cath-eter. Methods: Fifty-two patients with unexplained pleural effusion treated in the Department of Respiratory Medicine from January 2018 to February 2020 were selected, randomly divided into research group and control group. The research group used an arc bronchoscope for electronic bronchoscopy and diagnosis; the control group only used electronic bronchoscopy for examination and diagnosis. The definite diagnosis rate of pleural effusion, operation time, pathological tissue re-sults and surgical complications were analyzed. Results: The diagnosis rate of the study group was higher than that of the control group (25/26 - 19/26, the diagnosis rate was 96% - 73%), and the difference was statistically significant (P < 0.05). Tuberculous pleurisy with the most pathological diagnosis of pleural effusion of unknown origin is followed by malignant tumors. The operation time of the two groups was compared. The operation time of the study group was 38.15 ± 7.5 minutes; the operation time of the control group was 52.23 ± 8.2 minutes. The difference between the two groups was statistically significant (P < 0.05). The incidence of complications was not statistically significant between the two groups. Conclusion: The diagnosis rate of pleural effusion for unknown reasons is higher and the operation time is shorter with the bronchoscope inserted through the arc catheter. The curative effect is good and worthy of clinical promotion.
文章引用:张永辉, 历风元. 弧形导管插入电子支气管镜诊疗不明原因胸腔积液的研究[J]. 临床医学进展, 2020, 10(3): 289-294. https://doi.org/10.12677/ACM.2020.103046

参考文献

[1] Munavvar, M., Khan, M.A., Edwards, J., et al. (2007) Theautoclavable Semirigthoracoscope: The Way Forward in Pleural Disease. European Respiratory Journal, 29, 571-574. [Google Scholar] [CrossRef] [PubMed]
[2] Zhang, J., Wu, J., Yang, Y., Liao, H., Xu, Z., Hamblin, L.T., Jiang, L., Depypere, L., Ang, K.L., He, J., et al. (2016) White Light, Autofluorescence and Narrow-Band Imaging Bronchosacopy for Diagnosing Airway Precancerous and Early Cancer Lesions: A Systematic Review and Meta Analysis. Journal of Thoracic Disease, 8, 3205-3216. [Google Scholar] [CrossRef] [PubMed]
[3] Kurimoto, N., Miyazawa, T., Okimasa, S., Maeda, A., Oiwa, H., Miyazu, Y. and Murayama, M. (2004) Endobronchial Ultrasonography Using a Guide Sheath Increases the Ability to Diagnose Peripheral Pulmonary Lesions Endoscopically. Chest, 126, 959-965. [Google Scholar] [CrossRef] [PubMed]
[4] Loddenkemper, R. (2018) Thoracoscopy State of the Art. European Respiratory Journal, 11, 213-221. [Google Scholar] [CrossRef] [PubMed]
[5] Gu, P., Zhao, Y.-Z., Jiang, L.-Y., Zhang, W., Xin, Y. and Han, B.-H. (2009) Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration for Staging of Lung Cancer: A Systematic Review and Meta-Analysis. European Journal of Cancer, 45, 1389-1396. [Google Scholar] [CrossRef] [PubMed]
[6] Hartman, J.E., Vanfleteren, L.E.G.W., van Rikxoort, E.M., Klooster, K. and Slebos, D.-J. (2019) Endobronchial Valves for Severe Emphysema. European Respiratory Review, 28, pii: 180121. [Google Scholar] [CrossRef] [PubMed]
[7] Low, S.-W., Lee, J.Z., Desai, H., Hsu, C.-H., Sam, A.R. and Knepler, J.L. (2019) Endobronchial Valves Therapy for Advanced Emphysema: A Metaanalysis of Randomized Trials. Journal of Bronchology & Interventional Pulmonology, 26, 81-89. [Google Scholar] [CrossRef
[8] Rahman, N.M., Maskell, N.A., West, A., Teoh, R., Arnold, A., Mackinlay, C., Peckham, D., Davies, C.W.H., Ali, N., Kinnear, W., et al. (2011) Intrapleural Use of Tissue Plas-minogen Activator and DNase in Pleural Infection. The New England Journal of Medicine, 365, 518-526. [Google Scholar] [CrossRef
[9] Hetzel, J., Maldonado, F., Ravaglia, C., Wells, A.U., Colby, T.V., Tomassetti, S., Ryu, J.H., Fruchter, O., Piciucchi, S., Dubini, A., et al. (2018) Transbronchial Cryobiopsies for the Di-agnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure. Respiration, 95, 188-200. [Google Scholar] [CrossRef] [PubMed]
[10] Fielding, D.I., Maldonado, F. and Murgu, S. (2014) Achieving Compe-tency in Bronchoscopy: Challenges and Opportunities. Respirology, 19, 472-482. [Google Scholar] [CrossRef] [PubMed]
[11] Wechsler, M.E., Laviolette, M., Rubin, A.S., Fiterman, J., Lapa e Silva, J.R., Shah, P.L., Fiss, E., Olivenstein, R., Thomson, N.C., Niven, R.M., et al. (2013) Bronchial Thermoplasty: Long-Term Safety and Effectiveness in Patients with Severe Persistent Asthma. Journal of Allergy and Clinical Im-munology, 132, 1295-1302. [Google Scholar] [CrossRef] [PubMed]
[12] 齐菲, 田庆, 李春燕, 等. 胸腔镜在不明原因胸腔积液中的临床临床应用[J]. 中华腔镜外科杂志, 2015(1): 35-38.
[13] 黄国华, 麦锦娟, 等. 电子支气管镜代替内科胸腔镜对渗出性胸腔积液的诊断价值研究[J]. 临床医学工程, 2012(19): 1654-1655.