[1]
|
Wang, C., Xu, J.Y., Yang, L., et al. (2018) Prevalence and Risk Factors of Chronic Obstructive Pulmonary Disease in China (the China Pulmonary Health [CPH] Study): A National Cross-Sectional Study. The Lancet, 391, 1706-1717.
https://doi.org/10.1016/S0140-6736(18)30841-9
|
[2]
|
Celli, B.R. and Wedzicha, J.A. (2019) Update on Clinical Aspects of COPD Reply. The New England Journal of Medicine, 381, 2485-2486. https://doi.org/10.1056/NEJMc1914600
|
[3]
|
GBD 2017 Causes of Death Collaborators (2018) Global, Regional, and National Age-Sex-Specific Mortality for 282 Causes of Death in 195 Countries and Territories, 1980-2017: A Systematic Analysis for the Global Burden of Disease Study 2017. The Lancet, 392, 1736-1788.
|
[4]
|
Mirza, S., Clay, R.D. and Koslow, M.A. (2018) COPD Guidelines: A Review of the 2018 GOLD Report. Mayo Clinic Proceedings, 93, 1488-1502. https://doi.org/10.1016/j.mayocp.2018.05.026
|
[5]
|
Kiyokawa, H. and Morimoto, M. (2020) Notch Signaling in the Mammalian Respiratory System, Specifically the Trachea and Lungs, in Development, Homeostasis, Regeneration, and Disease. Development, Growth & Differentiation, 62, 67-79. https://doi.org/10.1111/dgd.12628
|
[6]
|
Guruharsha, K.G., Kankel, M.W., Artavanis-Tsakonas, S., et al. (2012) The Notch Signalling System: Recent Insights into the Complexity of a Conserved Pathway. Nature Reviews Genetics, 13, 654-666. https://doi.org/10.1038/nrg3272
|
[7]
|
Siebel, C. and Lendahl, U. (2017) Notch Signaling in Development, Tissue Homeostasis, and Disease. Physiological Reviews, 97, 1235-1294. https://doi.org/10.1152/physrev.00005.2017
|
[8]
|
Bray, S. (1998) Notch Signalling in Drosophilia: Three Ways to Use a Pathway. Seminars in Cell and Developmental Biology, 9, 591-597. https://doi.org/10.1006/scdb.1998.0262
|
[9]
|
Jing, Y., Gimenes, J.A. and Mishra, R. (2019) Notch3 Contributes to Rhinovirus-Induced Goblet Cell Hyperplasia in COPD Airway Epithelial Cells. Thorax, 74, 18-32. https://doi.org/10.1136/thoraxjnl-2017-210593
|
[10]
|
Boucherat, O., Chakir, J. and Jeannotte, L. (2012) The Loss of Hoxa5 Function Promotes Notch-Dependent Goblet Cell Metaplasia in Lung Airways. Biology Open, 1, 677-691. https://doi.org/10.1242/bio.20121701
|
[11]
|
Xing, Y., Li, A., Borok, Z., et al. (2012) NOTCH1 Is Required for Regeneration of Clara Cells during Repair of Airway Injury. Stem Cells, 30, 946-955. https://doi.org/10.1002/stem.1059
|
[12]
|
Jiang, J., Xiao, K. and Chen, P. (2017) Notch Signaling in Lung Diseases. Experimental Lung Research, 43, 217-228.
https://doi.org/10.1080/01902148.2017.1306599
|
[13]
|
Agustí, A. and Hogg, J.C. (2019) Update on the Pathogenesis of Chronic Obstructive Pulmonary Disease. The New England Journal of Medicine, 381, 1248-1256. https://doi.org/10.1056/NEJMra1900475
|
[14]
|
王颖莹, 潘涛, 贾凡, 等. 人外周血初始CD4+T细胞向Th17细胞分化条件研究[J]. 检验医学与临床, 2017, 14(7): 948-950.
|
[15]
|
张晓军, 何韶衡. 老年COPD患者痰IL-18、-16、-4及IFN-γ水平的相关性研究及临床意义[J]. 实用医学杂志, 2005, 21(11): 1145-1147.
|
[16]
|
杨晶, 邝相如. CD4+T细胞亚群失衡在慢性阻塞性肺疾病中的临床意义[J]. 中国现代医学杂志, 2015, 25(1): 46-49.
|
[17]
|
李志芳, 张倩, 吴世满. 慢性阻塞性肺疾病患者外周血Th17、CD4+Treg细胞的检测及意义[J]. 国际呼吸杂志, 2014(1): 31-35.
|
[18]
|
周鹏, 梁爱武, 张惠敏, 等. 白介素-17在慢性阻塞性肺疾病中的表达变化研究概况[J]. 中国民族民间医药, 2016, 25(12): 55-57.
|
[19]
|
刘迪, 牛逸群, 疏欣杨, 等. 百令胶囊对慢性阻塞性肺疾病稳定期患者免疫、炎症及氧化应激指标的影响[J]. 世界中西医结合杂志, 2020, 15(3): 425-433.
|
[20]
|
张占强, 吴春艳, 方彬, 等. Th17/Treg、IL-17在慢性阻塞性肺疾病患者中的表达及与肺功能的相关性[J]. 现代中西医结合杂志, 2018, 27(22): 2419-2423.
|
[21]
|
郝小梅, 彭文照, 刘梅. 不同分期慢性阻塞性肺病患者T淋巴细胞亚群细胞因子变化及其与肺功能的相关性研究[J]. 广州医科大学报, 2018, 46(1): 7-10.
|
[22]
|
Diller, M.L., Kudchadkar, R.R., Delman, K.A., et al. (2016) Balancing Inflammation: The Link between Th17 and Regulatory T Cells. Mediators of Inflammation, 10, 219-226. https://doi.org/10.1155/2016/6309219
|
[23]
|
Duffy, S.P. (2019) Chronic Obstructive Pulmonary Disease: Evaluation and Management. Medical Clinics of North America, 103, 453-461. https://doi.org/10.1016/j.mcna.2018.12.005
|
[24]
|
谢东杰, 王爱迪, 吴晶魁, 等. Notch信号通路对CD4+T细胞分化及功能调控的研究进展[J]. 免疫学杂志, 2017, 33(12): 1100-1104.
|
[25]
|
Yang, X.N., Liu, X.J., Zhao, L.T., et al. (2016) Effects and Mechanisms of Notch Signaling Pathway on Immune Imbalance in Chronic Obstructive Pulmonary Disease. Chinese Journal of Tuberculosis and Respiratory Diseases, 39, 881-885.
|
[26]
|
Gu, X.Y., Chu, X., Zeng, X.L., et al. (2017) Effects of PM2.5 Exposure on the Notch Signaling Pathway and Immune Imbalance in Chronic Obstructive Pulmonary Disease. Environmental Pollution, 226, 163-173.
https://doi.org/10.1016/j.envpol.2017.03.070
|
[27]
|
D’Souza, B., Meloty-Kapella, L. and Weinmaster, G. (2010) Chapter Three-Canonical and Non-Canonical Notch Ligands. Current Topics in Developmental Biology, 92, 73-129. https://doi.org/10.1016/S0070-2153(10)92003-6
|
[28]
|
Ballester-López, C., Conlon, T.M., Ertüz, Z., et al. (2019) The Notch Ligand DNER Regulates Macrophage IFNγ Release in Chronic Obstructive Pulmonary Disease. EBioMedicine, 43, 562-575.
https://doi.org/10.1016/j.ebiom.2019.03.054
|
[29]
|
吴海兰, 辛晓峰. 上皮间充质转化与慢性阻塞性肺疾病的气道重塑[J]. 医学研究生学报, 2015, 28(9): 1004-1008.
|
[30]
|
Godinas, L., Corhay, J.L., Henket, M., et al. (2017) Increased Production of TGF-β1 from Sputum Cells of COPD: Relationship with Airway Obstruction. Cytokine, 99, 1-8. https://doi.org/10.1016/j.cyto.2017.06.018
|
[31]
|
Li, S., Hu, X., Wang, Z., et al. (2015) Different Profiles of Notch Signaling in Cigarette Smoke-Induced Pulmonary Emphysema and Bleomycin-Induced Pulmonary Fibrosis. Inflammation Research, 64, 363-371.
https://doi.org/10.1007/s00011-015-0816-y
|
[32]
|
Hussain, M., Xu, C., Ahmad, M., et al. (2017) Notch Signaling: Linking Embryonic Lung Development and Asthmatic Airway Remodeling. Molecular Pharmacology, 92, 676-693. https://doi.org/10.1124/mol.117.110254
|
[33]
|
33Tilley, A.E., Harvey, B.G., Heguy, et al. (2009) A Down-Regulation of the Notch Pathway in Human Airway Epithelium in Association with Smoking and Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine, 179, 457-466. https://doi.org/10.1164/rccm.200705-795OC
|
[34]
|
华华, 刘向国, 李杰. 补肾活血调营化痰方对慢性阻塞性肺疾病大鼠模型肺功能及转化生长因子-β1、炎性因子的影响[J]. 世界中西医结合杂志, 2019, 14(11): 1543-1546.
|
[35]
|
Mahmood, M.Q., Reid, D., Ward, C., et al. (2017) Transforming Growth Factor (TGF) β1 and Smad Signalling Pathways: A Likely Key to EMT-Associated COPD Pathogenesis. Respirology, 22, 133-140.
https://doi.org/10.1111/resp.12882
|
[36]
|
刘晨, 隋红. TGF-β信号通路介导胃癌EMT的研究进展[J]. 现代肿瘤医学, 2020, 28(3): 517-520.
|
[37]
|
Matsuno, Y., Coelho, A.L., Jarai, G., Westwick, J. and Hogaboam, C.M. (2012) Notch Signaling Mediates TGF-β1-Induced Epithelial-Mesenchymal Transition through the Induction of Snai1. The International Journal of Biochemistry & Cell Biology, 44, 776-789. https://doi.org/10.1016/j.biocel.2012.01.021
|
[38]
|
汤立建, 任敦强, 孙家兴, 等. Notch信号通路与肺纤维化关系的研究进展[J]. 青岛大学医学院学报, 2017, 53(5): 614-617.
|
[39]
|
魏胜全, 薛华, 王惠霞, 等. 罗红霉素联合N-乙酰半胱氨酸治疗慢性阻塞性肺疾病合并肺间质纤维化疗效及对患者肺功能的影响[J]. 陕西医学杂志, 2020, 49(5): 611-614.
|
[40]
|
Vancheri, C., Gili, E., Failla, M., et al. (2005) Bradykinin Differentiates Human Lung Fibroblasts to a Myofibroblast Phenotype via the B2 Receptor. The Journal of Allergy and Clinical Immunology, 116, 1242-1248.
https://doi.org/10.1016/j.jaci.2005.09.025
|
[41]
|
符策富, 仕丽, 胡少丹, 等. NOTCH信号通路与肺纤维化发病机制的研究进展[J]. 现代养生, 2019, 4(8): 140-141.
|
[42]
|
徐芳, 刘红梅, 黄莺. 银杏叶提取物对特发性肺间质纤维化成纤维细胞表型转化过程中NOTCH信号通路的影响[J]. 中国中西医结合急救杂志, 2016(4): 417-420.
|
[43]
|
Gustafsson, M.V., Zheng, X., Pereira, T., et al. (2005) Hypoxia Requires Notch Signaling to Maintain the Undifferentiated Cell State. Developmental Cell, 9, 617-628. https://doi.org/10.1016/j.devcel.2005.09.010
|
[44]
|
Kurosu, H., Yamamoto, M., Clark, J.D., et al. (2005) Suppression of Aging in Mice by the Hormone Klotho. Science, 309, 1829-1833. https://doi.org/10.1126/science.1112766
|
[45]
|
Masuda, H., Chikuda, H., Suga, T., Kawaguchi, H. and KuroO, M. (2005) Regulation of Multiple Ageing-Like Phenotypes by Inducible Klotho Gene Expression in Klotho Mutant Mice. Mechanisms of Ageing and Development, 126, 1274-1283. https://doi.org/10.1016/j.mad.2005.07.007
|
[46]
|
Li, L., Wang, Y., Gao, W., et al. (2015) Klotho Reduction in Alveolar Macrophages Contributes to Cigarette Smoke Extract-Induced Inflammation in Chronic Obstructive Pulmonary Disease. Journal of Biological Chemistry, 290, 27890-27900. https://doi.org/10.1074/jbc.M115.655431
|
[47]
|
Shen, N., Gong, T., Wang, J.D., et al. (2011) Cigarette Smoke Induced Pulmonary Inflammatory Responses Are Mediated by EGR-1/GGPPS/MAPK Signaling. The American Journal of Pathology, 178, 110-118.
https://doi.org/10.1016/j.ajpath.2010.11.016
|
[48]
|
Cui, W., Zhang, Z., Zhang, P., et al. (2018) Nrf2 Attenuates Inflammatory Response in COPD/Emphysema: Crosstalk with Wnt3a/b-Catenin and AMPK Pathways. Journal of Cellular and Molecular Medicine, 22, 3514-3525.
https://doi.org/10.1111/jcmm.13628
|
[49]
|
Qiu, J., Zhang, Y.N., Zheng, X., et al. (2018) Notch Promotes DNMT-Mediated Hypermethylation of Klotho Leads to COPD-Related Inflammation. Experimental Lung Research, 44, 368-377.
https://doi.org/10.1080/01902148.2018.1556749
|