不同种类干细胞巢的有序分布构成中医经络系统
System of Channels and Collaterals Constituted by Different Kinds of Stem Cell Nest in Ordinal Distribution
DOI: 10.12677/TCM.2021.101008, PDF,  被引量 下载: 2,080  浏览: 2,801 
作者: 张明娟：南京中医药大学，江苏 南京；张建新：江苏润华冷冻食品有限公司，江苏 兴化
关键词: 成体干细胞；干细胞巢；腧穴；经络系统；进化；多能干细胞；干细胞巢模型；大脑；奇经八脉；Adult Stem Cells； Stem Cell Nest； Acupoints； Meridian System； Evolution； Pluripotent Stem Cells； Stem Cell Nest Model； Brain； Eight Extra Meridians
摘要: 《黄帝内经》是中医学的奠基之作，指出经络是决死生、处百病的“灵枢”，意思为灵验的、灵妙的中枢系统。作者认为中医药物归经学说表明，中草药标本兼治中的“本源”和“干细胞”存在对应关系。经络是各种干细胞活动交流协同进化的巨系统，主要表现为干细胞巢的出现以及不同种类干细胞巢的有序分布。存在两条干细胞分化链和，分别对应于中医理论中的先天之本和后天之本。在上述认识基础上，本文对成体干细胞的分类作出第四次较大的修改，对奇经八脉的成体干细胞巢组成及其主要功能特征作出了新的诠释，回答了一些奇经八脉病候产生的原因，例如阴维脉的主要病候是心痛和抑郁。本文还给出了一些实验设想，例如循行分布于脊柱内侧的督脉第二支，主要是由卫星胶质细胞的成体干细胞巢构成，希望能够引起同行的研究兴趣，共同促进中医经络学说尽快地融入现代科学体系。
Abstract: The Yellow Emperor’s Classic of Medicine (Huangdi Neijing), is the foundation work of traditional Chinese medicine. It points out that meridians are the “miraculous pivot” to determine life and death and can be used to deal with all kinds of diseases. According to Chinese herbal medicine theory, there is a corresponding relationship between “root cause” and “stem cells” in the Chinese herbal medicine treatment of both symptoms and root causes of a disease. Meridians are a giant system for the exchange and coevolution of various stem cells, which are mainly manifested as the emergence of stem cell nests and the orderly distribution of different types of stem cell nests. There are two stem cell differentiation chains, and , which correspond to innate and acquired basis in traditional Chinese medicine theory, respectively. Based on the above understanding, we made the fourth major revision to the classification of adult stem cells, made a new interpretation regarding the compositions of adult stem cell nests in eight extra meridians and their functional characteristics, and answered some causes of the eight abnormal extra meridians, such as heartache and depression, which are the main symptoms of Yinwei meridian. This paper also gives some experimental ideas, for example, the second branch of the Du meridian, which is distributed along the medial side of the spine, is mainly composed of adult stem cell nests of satellite glial cells, hoping to arouse the research interest of peers and jointly promote the integration of traditional Chinese medicine meridian theory into modern scientific system as soon as possible.
文章引用：张明娟, 张建新. 不同种类干细胞巢的有序分布构成中医经络系统[J]. 中医学, 2021, 10(1): 67-79. https://doi.org/10.12677/TCM.2021.101008

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