经皮穴位电刺激对颌骨骨折术后镇痛影响
Effect of Transcutaneous Acupoint Electrical Stimulation on Postoperative Analgesia of Jaw Fracture
DOI: 10.12677/ACM.2021.119613, PDF,    科研立项经费支持
作者: 王浩然*, 王 映, 孟 箭#:蚌埠医学院,安徽 蚌埠;徐州市中心医院,江苏 徐州
关键词: 经皮穴位电刺激颌骨骨折镇痛Transcutaneous Acupoint Electrical Stimulation Jaw Fracture Analgesia
摘要: 目的:探究经皮穴位电刺激在颌骨骨折术后病人镇痛中的作用。方法:本实验研究对象均来自徐州市中心医院口腔科2020年9月至2021年6月的76位需进行骨折切开复位内固定的患者。实验组:使用经静脉患者自控镇痛(patient-controlled intravenous analgesia, PCIA)。术后4小时对患者进行经皮穴位电刺激选取患者双侧合谷穴、劳宫穴,无创电极片连接经皮穴位电刺激仪后贴于穴位区域皮肤,同侧腧穴连接一组导线,疏密波,频率为2 Hz或100 Hz,脉冲宽度0.2~0.6 ms,强度为患者所能耐受的最大值,以穴位处有酸麻胀痛“得气”感为度。刺激时间为30 min。术后第1天开始,一天两次,每次时长30分钟。对照组与实验组区别在于仅连接电极片不给予电刺激,并告知患者仪器使用时无异常感觉。若上述治疗方法患者疼痛仍未缓解,追加使用氨酚曲马多。术后第6个小时、术后第1天、术后第2天测定患者VAS得分分别记为T0、T1、T2。镇痛泵用量情况及有效按压次数,氨酚曲马多平均使用剂量,术后出现头晕、恶心、腹胀、尿潴留并发症。结果:实验组与对照组患者T0时VAS平均得分依次为(1.54 ± 0.57)分,(1.65 ± 0.52)分,t值为1.045,P值为0.298,差异无统计学意义;实验组与对照组患者T1时VAS平均得分依次为(2.62 ± 0.67)分,(3.23 ± 0.71)分,t值为4.714,P值 < 0.0001,差异有统计学意义;实验组与对照组患者T2时VAS平均得分依次为(1.39 ± 0.49)分,(1.78 ± 0.56)分,t值为3.398,P值 < 0.0001,差异有统计学意义。实验组与对照组患者有效按压次数依次为(3.39 ± 0.89)次,(4.57 ± 1.18)次,t值为6.053,P值 < 0.0001,差异有统计学意义;实验组与对照组患者PCIA药物使用剂量依次为(94.80 ± 4.20) mg,(97.10 ± 2.93) mg,t值为3.354,P值为0.001,差异有统计学意义。两组患者均未追加氨酚曲马多。实验组患者有5例发生术后并发症,具体为发生头晕、恶心、腹胀、尿潴留例数依次为1、2、1、1。对照组患者有13例发生术后并发症发生头晕、恶心、腹胀、尿潴留例数依次为3、6、2、2。两组患者X2值为4.659,P值为0.031,两组患者差异有统计学意义。结论:经皮穴位电刺激能减轻颌骨骨折患者术后疼痛、减少镇痛药物用量及术后并发症。
Abstract: Objective: The objective is to explore the effect of percutaneous acupoint electrical stimulation on postoperative analgesia of jaw fracture patients. Methods: Seventy-six patients requiring open reduction and internal fixation of fractures were enrolled in this study from September 2020 to June 2021 in the Department of Stomatology, Xuzhou Central Hospital. Experimental group was the use of intravenous patient-controlled analgesia (patient-controlled intravenous analgesia lPCIA). Postoperative 4 hours, the patients were put percutaneous acupoint electrical stimulation with bilateral valley cave, laogong, noninvasive percutaneous electrodes connection point which sticked on the skin, ipsilateral developments to connect a group of lead, the density wave, the frequency of 2 Hz or 100 Hz; pulse width is 0.2~0.6 ms; The intensity is the maximum that the patient can tolerate. At the acupoint, there is acid hemp pain “get gas” feeling for degree. The stimulation time was 30 min. On the first day after surgery, the patients were treated twice a day for 30 minutes each time. The difference between the control group and the experimental group was that only electrodes were connected without electrical stimulation, and patients were informed that there was no abnormal sensation during the use of the instrument. If the patient’s pain is not relieved by the above treatment methods, amphenol tramadol is additionally used. VAS scores of the patients were recorded as T0, T1 and T2 at 6 h, 1 day and 2 days after surgery, respectively. Analgesic pump dosage and effective pressing times, average dose of amphenol tramadol, postoperative dizziness, nausea, abdominal distention, urinary retention complications were recorded. Results: The mean VAS scores of the experimental group and the control group at T0 were (1.54 ± 0.57) points, (1.65 ± 0.52) points; t value was 1.045; P value was 0.298; the difference was not statistically significant. The mean VAS scores of the experimental group and the control group at T1 were (2.62 ± 0.67) points, (3.23 ± 0.71) points; t value was 4.714; P value < 0.0001; the difference was statistically significant. The mean VAS scores of the experimental group and the control group at T2 were (1.39 ± 0.49) points and (1.78 ± 0.56) points, respectively, with t value of 3.398 and P value < 0.0001, indicating statistically significant differences. The effective pressing times of experimental group and control group were (3.39 ± 0.89) times, (4.57 ± 1.18) times; t value was 6.053 and P value < 0.0001; the difference was statistically significant. The dose of PCIA in experimental group and control group was (94.80 ± 4.20) mg, (97.10 ± 2.93) mg; t value was 3.354; P value was 0.001; the difference was statistically significant. No additional amphenol tramadol was added in both groups. There were 5 cases of postoperative complications in the experimental group, including dizziness, nausea, abdominal distension and urinary retention, which were 1, 2, 1 and 1 respectively. There were 13 patients in the control group with postoperative complications including dizziness, nausea and abdominal distension. The cases of urinary retention were 3, 6, 2 and 2 respectively. X2 value of the two groups was 4.659 and P value was 0.031, indicating the difference between the two groups. It was statistically significant. Conclusion: Percutaneous acupoint electrical stimulation can reduce postoperative pain, analgesic drug dosage and postoperative complications in patients with jaw fracture.
文章引用:王浩然, 王映, 孟箭. 经皮穴位电刺激对颌骨骨折术后镇痛影响[J]. 临床医学进展, 2021, 11(9): 4199-4205. https://doi.org/10.12677/ACM.2021.119613

参考文献

[1] Silva, T.C.G., Maranhão Filho, A.W.A., Alencar, M.G.M., De Bortoli, M.M. and Vasconcelos, B.C.E. (2019) Mandibular Fracture after Third Molar Removal: A Case Report. General Dentistry, 67, e7-e10.
[2] Bede, S.Y.H., Ismael, W.K. and Al-Assaf, D. (2017) Characteristics of Mandibular Injuries Caused by Bullets and Improvised Explosive Devices: A Comparative Study. International Journal of Oral and Maxillofacial Surgery, 46, 1271-1275. [Google Scholar] [CrossRef] [PubMed]
[3] Relja, B., Menke, J., Wagner, N., et al. (2016) Effects of Positive Blood Alcohol Concentration on Outcome and Systemic Interleukin-6 in Major Trauma Patients. Injury, 47, 640-645. [Google Scholar] [CrossRef] [PubMed]
[4] 宋晶年. 背根神经节P2X7受体在术后急慢性痛转化中的作用[D]: [硕士学位论文]. 广州: 广州医科大学, 2017.[CrossRef
[5] 王国云. 口腔颌面部术后疼痛调查及镇痛治疗[J]. 中外医疗, 2014(27): 57-58.
[6] 罗希. 头颈部恶性肿瘤游离皮瓣移植修复术后谵妄危险因素的相关性分析[D]: [硕士学位论文]. 青岛: 山东大学, 2019.
[7] 余晓宁, 蔡洁琛, 黄利浩, 等. 口腔颌面部手术术后谵妄危险因素的Meta分析[J]. 中华口腔医学研究杂志(电子版), 2019, 13(3): 166-173.
[8] Das, R., Deshmukh, J., Asif, K., Sindhura, H., Devarathanamma, M.V. and Jyothi, L. (2019) Comparative Evaluation of Analgesic and Anti-Inflammatory Efficacy of Ibuprofen and Traumeel after Periodontal Flap Surgery: A Randomized Triple-Blind Clinical Trial. Journal of Indian Society of Periodontology, 23, 549-553. [Google Scholar] [CrossRef] [PubMed]
[9] 辛志祥, 陶智蔚, 郑永超, 吕翔. 区域神经阻滞在口腔颌面肿瘤股前外侧皮瓣修复术后镇痛中的临床应用[J]. 中国口腔颌面外科杂志, 2019, 17(2): 159-162.
[10] Zhang, X., Sun, C., Bai, X. and Zhang, Q. (2018) Efficacy and Safety of Lower Extremity Nerve Blocks for Postoperative Analgesia at Free Fibular Flap Donor Sites. Head Neck, 40, 2670-2676. [Google Scholar] [CrossRef] [PubMed]
[11] Nascimento, F.F., Marques, V.I., Crociolli, G.C., Nicácio, G.M., Nicácio, I.P.A.G. and Cassu, R.N. (2019) Analgesic Efficacy of Laser Acupuncture and Electroacupuncture in Cats Undergoing Ovariohysterectomy. The Journal of Veterinary Medical Science, 81, 764-770. [Google Scholar] [CrossRef] [PubMed]
[12] Jalali, S., Moradi Majd, N., Torabi, S., Habibi, M., Homayouni, H. and Mohammadi, N. (2015) The Effect of Acupuncture on the Success of Inferior Alveolar Nerve Block for Teeth with Symptomatic Irreversible Pulpitis: A Triple-Blind Randomized Clinical Trial. Journal of Endodontics, 41, 1397-1402. [Google Scholar] [CrossRef] [PubMed]
[13] Melzack, R. and Wall, P.D. (1965) Pain Mechanisms: A New Theory. Science, 150, 971-979. [Google Scholar] [CrossRef] [PubMed]
[14] 张云霄, 李宗超, 陈冀衡, 等. 术前焦虑对胸腔镜肺癌根治术后患者早期预后的影响[J]. 中国肺癌杂志, 2019, 22(11): 714-718.
[15] Ana, M., Carsten, B., Jelena, J., et al. (2018) Psychological Factors as Predictors of Early Postoperative Pain after Open Nephrectomy. Journal of Pain Research, 11, 955-966. [Google Scholar] [CrossRef
[16] 江群, 莫云长, 金丹, 等. 加速康复外科理念下穴位刺激对甲状腺癌根治术患者恢复质量的影响: 随机对照研究[J]. 中国针灸, 2019, 39(12): 1289-1293.
[17] 张俊烁, 褚忠华, 方喜, 等. 不同术中保温对开腹手术患者低体温及手术部位感染的影响[J]. 中国临床药理学杂志, 2015, 31(18): 1834-1836.
[18] 梁汉生, 李奕楠, 冯艺. 经皮穴位电刺激的麻醉前预保温作用观察[J]. 针刺研究, 2019, 44(10): 747-751.
[19] 高军龙, 李玉兰. 浅谈经皮穴位电刺激在围麻醉期的多种作用[J]. 中国针灸, 2015, 35(3): 269-273.
[20] 胡先华. 经皮穴位电刺激辅助全身麻醉减少镇痛药及其副作用的随机对照研究[J]. 现代生物医学进展, 2015, 15(18): 3478-3483.
[21] Huizhou, L., Chuan, W., Caizhen, Y., et al. (2019) Cardioprotective Effect of Transcutaneous Electrical Acupuncture Point Stimulation on Perioperative Elderly Patients with Coronary Heart Disease: A Prospective, Randomized, Controlled Clinical Trial. Clinical Interventions in Aging, 14, 1607-1614. [Google Scholar] [CrossRef
[22] Ni, X., Xie, Y., Wang, Q., et al. (2012) Cardioprotective Effect of Transcutaneous Electric Acupoint Stimulation in the Pediatric Cardiac Patients: A Randomized Controlled Clinical Trial. Paediatric Anaesthesia, 22, 805-811. [Google Scholar] [CrossRef] [PubMed]
[23] Lu, Z., et al. (2010) Effect of Electroacupuncture Preconditioning on Serum S100beta and NSE in Patients Undergoing Craniocerebral Tumor Resection. Chinese Journal of Integrative Medicine, 16, 229-233. [Google Scholar] [CrossRef] [PubMed]
[24] Wei, W., et al. (2020) Pulmonary Protection of Transcutaneous Electrical Acupoint Stimulation in Gynecological Laparoscopic Surgery: A Randomized Controlled Trial. Experimental and Therapeutic Medicine, 19, 511-518. [Google Scholar] [CrossRef] [PubMed]
[25] 刘明富. 经皮穴位电刺激对气腹后肝肾功能异常的保护作用研究[D]: [硕士学位论文]. 西安: 中国人民解放军空军军医大学, 2016.
[26] 关啸, 崔晓光. 针刺镇痛的研究进展[J]. 医学综述, 2019, 25(24): 4972-4975, 4980.
[27] Tu, Q., Gan, J., Shi, J., et al. (2019) Effect of Transcutaneous Electrical Acupoint Stimulation on Postoperative Analgesia after Ureteroscopic Lithotripsy: A Randomized Controlled Trial. Urolithiasis, 47, 279-287. [Google Scholar] [CrossRef] [PubMed]
[28] 中华医学会麻醉学分会“穴位刺激围术期应用专家共识”工作小组. 穴位刺激围术期应用专家共识[J]. 中华麻醉学杂志, 2017, 37(10): 1153-1157, 1158.
[29] 纪秀波. 经皮穴位电刺激辅助静脉全麻对妇科宫腔镜手术患者镇痛效果的影响[J]. 浙江中医药大学学报, 2018, 42(10): 874-878. [Google Scholar] [CrossRef