[1]
|
潘理会, 张平, 李春辉. PI3K/AKT/mTOR信号传导通路在胃癌中的研究进展[J/OL]. 承德医学院学报, 2016, 33(4): 324-327. https://doi.org/10.15921/j.cnki.cyxb.2016.04.047
|
[2]
|
刘红兵, 张皓渝, 林兆博, 等. PTEN/PI3K/AKT信号通路系统与胃癌研究进展[J]. 中国现代普通外科进展, 2020, 23(3): 244-247.
|
[3]
|
Yu, L., Wei, J. and Liu, P. (2022) Attacking the PI3K/Akt/mTOR Signaling Pathway for Targeted Therapeutic Treatment in Hu-man Cancer. Seminars in Cancer Biology, 85, 69-94. https://doi.org/10.1016/j.semcancer.2021.06.019
|
[4]
|
Herschbein, L. and Liesveld, J.L. (2018) Dueling for Dual Inhibition: Means to Enhance Effectiveness of PI3K/Akt/ mTOR Inhibitors in AML. Blood Reviews, 32, 235-248. https://doi.org/10.1016/j.blre.2017.11.006
|
[5]
|
Revathidevi, S. and Munirajan, A.K. (2019) Akt in Cancer: Media-tor and More. Seminars in Cancer Biology, 59, 80-91. https://doi.org/10.1016/j.semcancer.2019.06.002
|
[6]
|
Mafi, S., Mansoori, B., Taeb, S., et al. (2021) mTOR-Mediated Regulation of Immune Responses in Cancer and Tumor Mi-croenvironment. Frontiers in Immunology, 12, Article ID: 774103. https://doi.org/10.3389/fimmu.2021.774103
|
[7]
|
Laplante, M. and Sabatini, D.M. (2009) mTOR Signaling at a Glance. Journal of Cell Science, 122, 3589-3594.
https://doi.org/10.1242/jcs.051011
|
[8]
|
Liu, G.Y. and Sabatini, D.M. (2020) mTOR at the Nexus of Nutrition, Growth, Ageing and Disease. Nature Reviews. Molecular Cell Biology, 21, 183-203. https://doi.org/10.1038/s41580-019-0199-y
|
[9]
|
Fattahi, S., Amjadi-Moheb, F., Tabaripour, R., et al. (2020) PI3K/AKT/mTOR Signaling in Gastric Cancer: Epigenetics and beyond. Life Sciences, 262, Article ID: 118513. https://doi.org/10.1016/j.lfs.2020.118513
|
[10]
|
Ediriweera, M.K., Tennekoon, K.H. and Samarakoon, S.R. (2019) Role of the PI3K/AKT/mTOR Signaling Pathway in Ovarian Cancer: Biological and Therapeutic Significance. Seminars in Cancer Biology, 59, 147-160.
https://doi.org/10.1016/j.semcancer.2019.05.012
|
[11]
|
Tan, A.C. (2020) Targeting the PI3K/Akt/mTOR Pathway in Non-Small Cell Lung Cancer (NSCLC). Thoracic Cancer, 11, 511-518. https://doi.org/10.1111/1759-7714.13328
|
[12]
|
Shorning, B.Y., Dass, M.S., Smalley, M.J., et al. (2020) The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling. International Journal of Molecular Sciences, 21, Article No. 4507.
https://doi.org/10.3390/ijms21124507
|
[13]
|
陈正军, 黄翔. PI3K信号通路及其抑制剂抗恶性肿瘤的研究进展[J]. 实用医院临床杂志, 2011, 8(3): 140-143.
|
[14]
|
周康杰, 胡楠, 吴学雨, 等. TGF-β、PD-L1及PI3K蛋白在胃癌组织中的表达及临床意义[J]. 现代肿瘤医学, 2022, 30(13): 2394-2399.
|
[15]
|
Song, Y., Li, Z., Liu, X., et al. (2017) The Wnt/β-Catenin and PI3K/Akt Signaling Pathways Promote EMT in Gastric Cancer by Epigenetic Regulation via H3 Lysine 27 Acetylation. Tumor Biology, 39, No. 7.
https://doi.org/10.1177/1010428317712617
|
[16]
|
刘东刚, 白春华, 张旭东. PI3K/AKT/MTOR信号通路关键信号分子在胃癌组织中的表达及与临床特征的关系[J]. 癌症进展, 2018, 16(12): 1506-1510.
|
[17]
|
Wang, Z. (2021) Regulation of Cell Cycle Progression by Growth Factor-Induced Cell Signaling. Cells, 10, Article No. 3327. https://doi.org/10.3390/cells10123327
|
[18]
|
Chang, F., Lee, J.T., Navolanic, P.M., et al. (2003) Involvement of PI3K/Akt Pathway in Cell Cycle Progression, Apoptosis, and Neoplastic Transformation: A Target for Cancer Chemo-therapy. Leukemia, 17, 590-603.
https://doi.org/10.1038/sj.leu.2402824
|
[19]
|
Din, S.R.U., Nisar, M.A., Ramzan, M.N., et al. (2021) Latcripin-7A from Lentinula edodes C91-3 Induces Apoptosis, Autophagy, and Cell Cycle Arrest at G1 Phase in Human Gastric Cancer Cells via Inhibiting PI3K/Akt/mTOR Signaling. European Journal of Pharmacology, 907, Article ID: 174305. https://doi.org/10.1016/j.ejphar.2021.174305
|
[20]
|
Kim, S.M., Vetrivel, P., Ha, S.E., et al. (2020) Apigetrin Induces Extrinsic Apoptosis, Autophagy and G2/M Phase Cell Cycle Arrest through PI3K/AKT/mTOR Pathway in AGS Human Gastric Cancer Cell. The Journal of Nutritional Biochemistry, 83, Article ID: 108427. https://doi.org/10.1016/j.jnutbio.2020.108427
|
[21]
|
Lee, H.J., Venkatarame Gowda Saralamma, V., Kim, S.M., et al. (2018) Pectolinarigenin Induced Cell Cycle Arrest, Autophagy, and Apoptosis in Gastric Cancer Cell via PI3K/AKT/mTOR Signaling Pathway. Nutrients, 10, Article No. 1043. https://doi.org/10.3390/nu10081043
|
[22]
|
Morana, O., Wood, W. and Gregory, C.D. (2022) The Apoptosis Para-dox in Cancer. International Journal of Molecular Sciences, 23, Article No. 1328. https://doi.org/10.3390/ijms23031328
|
[23]
|
向青, 徐波, 范慕贞. 细胞凋亡与肿瘤[J]. 中日友好医院学报, 2002, 16(3): 181-184.
https://doi.org/10.3969/j.issn.1001-0025.2002.03.017
|
[24]
|
Rong, L., Li, Z., Leng, X., et al. (2020) Salidroside In-duces Apoptosis and Protective Autophagy in Human Gastric Cancer AGS Cells through the PI3K/Akt/mTOR Pathway. Biomedicine & Pharmacotherapy, 122, Article ID: 109726.
https://doi.org/10.1016/j.biopha.2019.109726
|
[25]
|
Luo, Y., et al. (2023) Vernodalin Suppresses Tumor Prolifera-tion and Increases Apoptosis of Gastric Cancer Cells through Attenuation of FAK/PI3K/AKT/mTOR and MAPKs Sig-naling Pathways. Current Pharmaceutical Biotechnology, 24, 708-717. https://pubmed.ncbi.nlm.nih.gov/35909270/
|
[26]
|
Wang, R.B., et al. (2022) Biologically Synthesized Black Gin-ger-Selenium Nanoparticle Induces Apoptosis and Autophagy of AGS Gastric Cancer Cells by Suppressing the PI3K/Akt/mTOR Signaling Pathway. Journal of Nanobiotechnology, 20, 441. https://pubmed.ncbi.nlm.nih.gov/36209164/
|
[27]
|
耿军辉, 张丽军, 王亚丽, 等. PI3K/Akt信号通路与肿瘤血管新生的研究进展[J]. 现代肿瘤医学, 2018, 26(9): 1462-1466.
|
[28]
|
熊义富, 李丽, 徐浩, 等. HIF-1α/VEGF在肝细胞癌的表达及其与肿瘤血管生成的关系[J]. 川北医学院学报, 2013, 28(6): 530-533.
|
[29]
|
Mahfouz, N., Tahtouh, R., Alaaeddine, N., et al. (2017) Gastrointestinal Cancer Cells Treatment with Bevacizumab Activates a VEGF Autoregula-tory Mechanism Involving Telomerase Catalytic Subunit hTERT via PI3K-AKT, HIF-1α and VEGF Receptors. PLOS ONE, 12, e0179202. https://doi.org/10.1371/journal.pone.0179202
|
[30]
|
刘强, 孙少明, 王文俊. miR-101-3p在胃癌中的表达及其靶向STC-1基因调控PI3K/AKT信号通路对癌细胞侵袭转移和血管生成的影响[J]. 肿瘤防治研究, 2022, 49(12): 1223-1231.
|
[31]
|
宫海涛, 程鸽, 辛玲, 等. EGFR和PI3K在进展期胃癌中的表达及临床意义研究[J]. 中国当代医药, 2012, 19(13): 14-16.
|
[32]
|
袁火忠, 黄兴伟, 谢敏明, 等. Grb2和mTOR在胃癌中的表达[J]. 广东医学, 2011, 32(19): 2544-2545.
https://doi.org/10.13820/j.cnki.gdyx.2011.19.057
|
[33]
|
胡雅鑫. PLR-3通过调控PI3K/Akt信号通路促进胃癌腹膜转移的研究[J]. 医药论坛杂志, 2023, 44(4): 26-30.
|
[34]
|
Xing, C.G., Zhu, B.S., Fan, X.Q., et al. (2009) Effects of LY294002 on the Invasiveness of Human Gastric Cancer in Vivo in Nude Mice. World Journal of Gastroenterology, 15, 5044-5052. https://doi.org/10.3748/wjg.15.5044
|
[35]
|
费洪荣, 陈洪蕾, 辛晓明, 等. Akt抑制剂perifosine抑制胃癌细胞增殖并诱导凋亡的实验研究[J]. 中国病理生理杂志, 2011, 27(6): 1084-1089.
|
[36]
|
张瑞瑞, 刘磊, 刘莹, 等. 依维莫司联合顺铂对胃癌细胞株SGC7901细胞周期的影响[J]. 第三军医大学学报, 2011, 33(18): 1951-1955. https://doi.org/10.16016/j.1000-5404.2011.18.032
|