氟伐他汀钠的合成工艺研究

The Synthesis Process Research of Fluvastatin Sodium

摘要: 本文根据我国心脑血管疾病的增加和人口老龄化的到来，引出调血脂观念的重要性，从而介绍降血脂药物氟伐他汀钠，进而对氟伐他汀钠的合成工艺进行了全面的研究和探索。得出第四种合成工艺是最佳的，适合工业化大生产，可以开发出高效的内部合成工艺，值得推广，并给出了某些良好的建议。 According to the increasing of cardiovascular disease and the coming of aging population in our country, draws out the importance of lipid regulators, so as to introduce Fluvastatin sodium of lipid-lowering drugs, and carries on comprehensive research and exploration Fluvastatin sodium of synthesis routes. Because of it’s for industrial pro-duction and development of effective internal synthetic process, the fourth synthetic process is the best. And some good advice are be gived.