IJPN  >> Vol. 1 No. 3 (August 2012)

    人脐带间充质干细胞移植在神经系统疾病中的新进展
    The Latest Application Progress of Human Umbilical Cord-Derived Mesenchymal Stem Cells (hUC-MSCs) in Neurological Diseases

  • 全文下载: PDF(293KB) HTML   XML   PP.17-21   DOI: 10.12677/IJPN.2012.13005  
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作者:  

张德双,陈 娟:四川大学华西第二医院新生儿科

关键词:
脐带间充质干细胞移植神经系统疾病Human; Umbilical Cord; Mesenchymal Stem Cells; Transplantation; Nervous System Diseases

摘要:

人脐带组织富含间充质干细胞(MSCs),与其他来源的MSCs相比,具有来源丰富、容易提取、倍增时间短、免疫原性低、移植后长期存活、不涉及伦理问题等多种优点,近年来对其研究越来越多。在适宜的环境下,人脐带间充质干细胞(hUC-MSCs)可以分化为神经样细胞,移植于多种神经系统疾病动物模型后均可促进其神经功能恢复,现就此方面的最新研究及应用进展予以综述。

The mesenchymal stem cell is rich in human umbilical cord, compared with MSCs of other sources, hUC-MSCs have major advantages such as richer source, easier collection freedom, shorter doubling time, lower immunogenicity, longer-term survival after transplantation, no ethical implications and so on. In recent years, the investigation of hUC-MSCs has been growing. In appropriate circumstances, hUC-MSCs can differentiate into neuron-like cells, when transplanted into different animal models of neurological diseases can promote the recovery of neural function. Now, we will review the latest application progress of hUC-MSCs in Neurological Diseases.

文章引用:
张德双, 陈娟. 人脐带间充质干细胞移植在神经系统疾病中的新进展[J]. 国际神经精神科学杂志, 2012, 1(3): 17-21. http://dx.doi.org/10.12677/IJPN.2012.13005

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