学术期刊
切换导航
首 页
文 章
期 刊
投 稿
预 印
会 议
书 籍
新 闻
合 作
我 们
按学科分类
Journals by Subject
按期刊分类
Journals by Title
核心OA期刊
Core OA Journal
数学与物理
Math & Physics
化学与材料
Chemistry & Materials
生命科学
Life Sciences
医药卫生
Medicine & Health
信息通讯
Information & Communication
工程技术
Engineering & Technology
地球与环境
Earth & Environment
经济与管理
Economics & Management
人文社科
Humanities & Social Sciences
合作期刊
Cooperation Journals
首页
医药卫生
医学诊断
Vol. 3 No. 1 (March 2013)
期刊菜单
最新文章
历史文章
检索
领域
编委
投稿须知
文章处理费
最新文章
历史文章
检索
领域
编委
投稿须知
文章处理费
包裹液态氟碳超声造影剂的研究进展
Progress of Ultrasound Contrast Agent Containing Liquid Perfluorocarbons
DOI:
10.12677/MD.2013.31004
,
PDF
,
HTML
,
XML
,
被引量
下载: 4,090
浏览: 15,588
国家自然科学基金支持
作者:
曹众
*
,
张春阳
,
朱文健
,
李皓
:中山大学工学院生物医学工程,广州
关键词:
液态氟碳
;
超声造影剂
;
磷脂
;
高分子材料
;
二氧化硅
;
Liquid Perfluorocarbons; Ultrasound Contrast Agent; Lipid; Polymer; Silica
摘要:
随着纳米技术和超声分子成像技术的迅速发展,一种新型造影剂——液态氟碳超声造影剂应运而生。不同包膜材料的液态氟碳超声造影剂分别表现出不同的性质。本文就氟碳类超声造影剂的背景、材料、应用现状及展望等方面做一综述。
With the advancement of nanotechnology and ultrasound molecule imaging, a novel contrast agent has be- come a new research approach. Liquid perfluorocarbons coated with different materials as ultrasound contrast agents exhibit different characteristics. This article reviews the background, application and prospect of perfluorocarbon nanoparticle.
文章引用:
曹众, 张春阳, 朱文健, 李皓. 包裹液态氟碳超声造影剂的研究进展[J]. 医学诊断, 2013, 3(1): 15-20.
http://dx.doi.org/10.12677/MD.2013.31004
参考文献
[
1
]
M. S. Liu, D. M. Long. Perfluoroctylbromide as a diagnostic contrast medium in gastroenterography. Radiology, 1977, 122(1): 71-76.
[
2
]
T. Cyrus, P. M. Winter, C S. D. aruthers, et al. Magnetic reso- nance nanoparticles for cardiovascular molecular imaging and therapy. Expert Review of Cardiovascular Therapy, 2005, 3(4): 705-715.
[
3
]
R. Diaz-Lopez, N. Tsapis, M. Santin, et al. The performance of PEGylated nanocapsules of perfluorooctyl bromide as an ultra- sound contrast agent. Biomaterials, 2010, 31(7): 1723-1731.
[
4
]
G. M. Lanza, K. D. Wallace, M. J. Scott, et al. A novel site- targeted ultrasonic contrast agent with broad biomedical applica- tion. Circulation, 1996, 94(12): 3334-3340.
[
5
]
G. M. Lanza, P. M. Winter, S. D. Caruthers, et al. Magnetic reso- nance molecular imaging with nanoparticles. Journal of Nuclear Cardiology, 2004, 11(6): 733-743.
[
6
]
M. M. Kaneda, S. Caruthers, G. M. Lanza, et al. Perfluorocarbon nanoemulsions for quantitative molecular imaging and targeted therapeutics. Annals of Biomedical Engineering, 2009, 37(10): 1922-1933.
[
7
]
周洋, 郑元义, 冉海涛等. 叶酸受体靶向液态氟碳纳米粒造影剂的制备及体外寻靶[J]. 中国医学影像技术, 2012, 28(1): 52-54.
[
8
]
李奥, 王志刚. 液态氟碳纳米粒——一种多功能影像学造影剂[J]. 临床超声医学杂志, 2008, 10(12): 830-832.
[
9
]
沈红霞, 郑元义, 王志刚. 包裹液态氟碳的高分子超声造影剂的研究进展[J]. 中国介入影像与治疗学, 2010, 7(6): 684- 687.
[
10
]
杨扬, 王志刚, 郑元义等. 液态氟碳纳米脂质微球超声对比剂用于增强正常大鼠CT显像实验研究[J]. 中国医学影像技术, 2008, 24(9): 1341-1344.
[
11
]
刘莹莹. 液态氟碳纳米脂质微粒靶向识别存活心肌实验研究[D]. 华中科技大学, 2010.
[
12
]
P. S. Sheeran, S. Luois, P. A. Dayton, et al. Formulation and acoustic studies of a new phase-shift agent for diagnostic and therapeutic ultrasound. Langmuir, 2011, 27(17): 10412-10420.
[
13
]
W. Cui, J. Z. Bei, S. G. Wang, et al. Preparation and evaluation of poly(L-lactide-co-glycolide) (PLGA) microbubbles as a con- trast agent for myocardial contrast echocardiography. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2005, 73B(1): 171-178.
[
14
]
J. R. Lindner. Microbubbles in medical imaging: Current appli- cations and future directions. Nature Reviews Drug Discovery, 2004, 3(6): 527-533.
[
15
]
J. A. Straub, D. E. Chickering, C. C. Church, et al. Porous PLGA microparticles: AI-700, an intravenously administered ultra- sound contrast agent for use in echocardiography. Journal of Controlled Release, 2005, 108(1): 21-32.
[
16
]
A. L. Klibanov. Ultrasound molecular imaging with targeted micro- bubble contrast agents. Journal of Nuclear Cardiology, 2007, 14 (6): 876-884.
[
17
]
E. Pisani, N. Tsapis, J. Paris, et al. Polymeric nano/microcap- sules of liquid perfluorocarbons for ultrasonic imaging: Physical characterization. Langmuir, 2006, 22: 4397-4402.
[
18
]
F. Yuan, M. Dellian, D. Fukumura, et al. Vascular permeability in a human tumor xenograft: Molecular size dependence and cutoff size. Cancer Research, 1995, 55(17): 3752-3756.
[
19
]
G. M. Lanza, D. R. Abendschein, C. S. Hall, et al. In vivo mo- lecular imaging of stretch-induced tissue factor in carotid arter- ies with ligand-targeted nanoparticles. Journal of the American Society of Echocardiography, 2000, 13(6): 608-614.
[
20
]
R. Diaz-Lopez, N. Tsapis, M. Santin, et al. The performance of PEGylated nanocapsules of perfluorooctyl bromide as an ultrasound contrast agent. Biomaterials, 2010, 31(7): 1723-1731.
[
21
]
R. Diaz-Lopez, N. Tsapis, D. Libong, et al. Phospholipid deco- ration of microcapsules containing perfluorooctyl bromide used as ultrasound contrast agents. Biomaterials, 2009, 30(8): 1462- 1472.
[
22
]
E. Pisani, N. Tsapis, B. Galaz, M. Santin and B. Romain. Per- fluorooctyl bromide polymeric capsules as dual contrast agents for ultrasonography and magnetic resonance imaging. Advanced Functional Materials, 2008, 18(19): 2963-2971.
[
23
]
沈红霞. 包裹液态氟碳的PLGA微球增强HIFU能量沉积的实验研究[D]. 重庆医科大学, 2012.
[
24
]
李皓, 王建好, 张超, 蒋庆. 声控纳米超声造影剂的制备与性能研究[A]. 广东省生物医学工程学会成立32周年纪念大会[C]. 广州: 广东省生物医学工程学会, 2012: 162-169.
[
25
]
C. J. McDonald, M. J. Devon. Hollow latex particles: Synthesis and applications. Advances in Colloid and Interface Science, 2002, 99(3): 181-213.
[
26
]
J. Gallardo, P. Galliano, R. Moreno, et al. Bioactive sol-gel coat- ings for orthopaedic prosthesis. Journal of Sol-Gel Science and Technology, 2000, 19(1-3): 107-111.
[
27
]
J.-M. Yeh, C.-J. Weng, W.-J. Liao, et al. Anticorrosively enhanc- ed PMMA-SiO2 hybrid coatings prepared from the sol-gel ap- proach with MSMA as the coupling agent. Surface & Coatings Technology, 2006, 201: 1788-1795.
[
28
]
P. L. Lin, R. J. Eckersley and E. A. H. Hall. Ultrabubble: A lami- nated ultrasound contrast agent with narrow size range. Ad- vanced Materials, 2009, 21(38-39): 3949-3952.
[
29
]
H. Hu, H. Zhou, J. Du, et al. Biocompatiable hollow silica mi- crospheres as novel ultrasound contrast agents for in vivo imag- ing. Journal of Materials Chemistry, 2011, 21: 6576-6583.
[
30
]
X. Wang, H. Chen, Y. Chen, et al. Perfluorohex-ane-encapsulated mesoporous silica nanocapsules as enhancement agents for high- ly efficient High Intensity Focused Ultrasound (HIFU). Advanc- ed Materials, 2012, 24(6): 785-791.
投稿
为你推荐
友情链接
科研出版社
开放图书馆