AMB  >> Vol. 2 No. 1 (March 2013)

    Development of Genomic Structure and Function of Hepatitis E Virus

  • 全文下载: PDF(381KB) HTML   XML   PP.32-36   DOI: 10.12677/AMB.2013.21007  
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戊型肝炎病毒基因结构开放读码框顺反应元件Hepatitis E Virus (HEV); Gene Structure; Open Reading Frame (ORF); Cis-Reactive Elements (CRE)


Hepatitis E virus (HEV) is one of the most important pathogens of acute viral hepatitis prevailing in developing countries. There are four major genotypes of mammalian HEV, genotype 1 and 2 are restricted to human infection, and induce epidemic hepatitis E which is mainly transmitted by contaminated water; whereas genotype 3 and 4 are zoonotic causing sporadic cases which are common in developed countries. In recent years, much more attention has been paid to the structures of viral genes and the functions of viral proteins. The research progress achieved in such field will help us uncover the veil of HEV in pathogenesis and infection.

雷雅昕, 刘鹏, 王玲. 戊型肝炎病毒的基因组结构及生物学功能研究进展[J]. 微生物前沿, 2013, 2(1): 32-36.


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