猫传染性鼻气管炎病毒gB和gD序列比对

Comparison of the gB and gD Sequences of Feline Infectious Rhinotracheitis Virus

摘要: 【目的】比较猫传染性鼻气管炎病毒gB和gD序列差异。【方法】采用测序方法对传染性鼻气管炎病毒5株分离株和1株疫苗株的gB和gD序列进行序列测定，并比较核苷酸和氨基酸差异。【结果】结果表明分离株gB序列发生了部分变化，并且与疫苗株高度同源，其氨基酸也同样发生部分变化，gD序列没有变化。【结论】猫传染性鼻气管炎病毒分离株gB序列有变化，但与疫苗株同源性一致。

Abstract: [Objective] To compare the gB and gD sequences of the Feline Infectious Rhinotracheitis virus. [Methods] The gB and gD sequences of 5 isolates and 1 vaccine strain of Feline Infectious Rhi-notracheitis virus were sequenced, and the nucleotides and amino acids of them were compared. [Results] The gB sequences of the isolates were partially mutated and were highly homologous to the vaccine strain. The amino acids of the isolates were also partially mutated. The gD sequences were not mutated. [Conclusion] The gB sequences of Feline Infectious Rhinotracheitis virus isolates were mutated, but they were homologous with vaccine strain.