|
[1]
|
Harvey Lodish, A., Lawrence Zipursky, S., Matsudaira, P., et al. (2000) Molecular Cell Biology. 4th Edition, Springer, Berlin.
|
|
[2]
|
Schweizer, J., Bowden, P.E., Coulombe, P.A., et al. (2006) New Consensus Nomenclature for Mammalian Keratins. Journal of Cell Biology, 174, 169-174. [Google Scholar] [CrossRef] [PubMed]
|
|
[3]
|
Bragulla, H.H. and Homberger, D.G. (2009) Structure and Functions of Keratin Proteins in Simple, Stratified, Keratinized and Cornified Ep-ithelia. Journal of Anatomy, 214, 516-559. [Google Scholar] [CrossRef] [PubMed]
|
|
[4]
|
Kurokawa, I., Takahashi, K., Moll, I. and Moll, R. (2011) Expression of Keratins in Cutaneous Epithelial Tumors and Related Disor-ders-Distribution and Clinical Significance. Experimental Dermatology, 20, 217-228. [Google Scholar] [CrossRef] [PubMed]
|
|
[5]
|
Pan, X., Hobbs, R.P. and Coulombe, P.A. (2013) The Ex-panding Significance of Keratin Intermediate Filaments in Normal and Diseased Epithelia. Current Opinion in Cell Biol-ogy, 25, 47-56. [Google Scholar] [CrossRef] [PubMed]
|
|
[6]
|
Peiguo, G.C., Sean, K.L. and Lawrence, M.W. (2009) Keratin Expression in Endocrine Organs and Their Neoplasms. Endocrine Pathology, 20, 1-10. [Google Scholar] [CrossRef] [PubMed]
|
|
[7]
|
Haines, R.L. and Lane, E.B. (2012) Keratins and Disease at a Glance. Journal of Cell Science, 125, 3923-3928. [Google Scholar] [CrossRef] [PubMed]
|
|
[8]
|
Justin, T.J., Pierre, A.C., Raymond, K. and Bishr, M.O. (2018) Types I and II Keratin Intermediate Filaments. Cold Spring Harbor Perspectives in Biology, 10, a018275. [Google Scholar] [CrossRef] [PubMed]
|
|
[9]
|
Fanny, L., Kristin, S., Jamal, E.B. and Thomas, M.M. (2015) Regulation of Keratin Network Organization. Current Opinion in Cell Biology, 32, 56-65. [Google Scholar] [CrossRef] [PubMed]
|
|
[10]
|
Ramms, L., Fabris, G., Windoffer, R, et al. (2013) Keratins as the Main Component for the Mechanical Integrity of Keratinocytes. Proceedings of the National Academy of Sciences of the United States of America, 110, 18513-18518. [Google Scholar] [CrossRef] [PubMed]
|
|
[11]
|
Seltmann, K., Fritsch, A.W., Kas, J.A. and Magin, T.M. (2013) Keratins Significantly Contribute to Cell Stiffness and Impact Invasive Behavior. Proceedings of the National Academy of Sciences of the United States of America, 110, 18507-18512. [Google Scholar] [CrossRef] [PubMed]
|
|
[12]
|
Chung, B.M., Rotty, J.D. and Coulombe, P.A. (2013) Networking Galore: Intermediate Filaments and Cell Migration. Current Opinion in Cell Biology, 25, 600-612. [Google Scholar] [CrossRef] [PubMed]
|
|
[13]
|
Seltmann, K., Roth, W., Kroger, C., Loschke, F., Lederer, M., Huttelmaier, S. and Magin, T.M. (2013) Keratins Mediate Localization of Hemi-desmosomes and Repress Cell Motility. Journal of Investigative Dermatology, 133, 181-190. [Google Scholar] [CrossRef] [PubMed]
|
|
[14]
|
Fortier, A.M., Asselin, E. and Cadrin, M. (2013) Keratin 8 and 18 Loss in Epithelial Cancer Cells Increases Collective Cell Migration and Cisplatin Sensitivity through Claudin1 Up-Regulation. The Journal of Biological Chemistry, 288, 11555-11571. [Google Scholar] [CrossRef]
|
|
[15]
|
Kroger, C., Loschke, F., Schwarz, N., Windoffer, R., Leube, R.E. and Magin, T.M. (2013) Keratins Control Intercellular Adhesion Involving PKC-Alpha-Mediated Desmoplakin Phosphorylation. Journal of Cell Biology, 201, 681-692. [Google Scholar] [CrossRef] [PubMed]
|
|
[16]
|
Wallace, L., Roberts-Thompson, L. and Reichelt, J. (2012) Deletion of K1/K10 Does Not Impair Epidermal Stratification But Affects Desmosomal Structure and Nuclear Integrity. Journal of Cell Science, 125, 1750-1758. [Google Scholar] [CrossRef] [PubMed]
|
|
[17]
|
Snider, N.T. and Omary, M.B. (2014) Post-Translational Modifications of Intermediate Filament Proteins: Mechanisms and Functions. Nature Reviews Molecular Cell Biology, 15, 163-177. [Google Scholar] [CrossRef] [PubMed]
|
|
[18]
|
Hyun, J.K., Won, J.C. and Chang, H.L. (2015) Phosphorylation and Reor-ganization of Keratin Networks: Implications for Carcinogenesis and Epithelial Mesenchymal Transition. Biomolecules & Therapeutics, 23, 301-312. [Google Scholar] [CrossRef] [PubMed]
|
|
[19]
|
Holle, A.W., Kalafat, M., Ramos, A.S., Seufferlein, T., Kemke-mer, R. and Spatz, J.P. (2017) Intermediate Filament Reorganization Dynamically Influences Cancer Cell Alignment and Migration. Scientific Reports, 7, 45152. [Google Scholar] [CrossRef] [PubMed]
|
|
[20]
|
Windoffer, R., Beil, M., Magin, T.M. and Leube, R.E. (2011) Cytoskeleton in Motion: The Dynamics of Keratin Intermediate Filaments in Epithelia. Journal of Cell Biology, 194, 669-678. [Google Scholar] [CrossRef] [PubMed]
|
|
[21]
|
Bouameur, J.E., Schneider, Y., Begre, N., et al. (2013) Phosphoryla-tion of Serine 4642 in the C-Terminus of Plectin by MNK2 and PKA Modulates Its Interaction with Intermediate Fila-ments. Journal of Cell Science, 126, 4195-4207. [Google Scholar] [CrossRef] [PubMed]
|
|
[22]
|
Liu, Y.H., Cheng, C.C., Ho, C.C., et al. (2011) Plectin Deficiency on Cy-toskeletal Disorganization and Transformation of Human Liver Cells in Vitro. Medical Molecular Morphology, 44, 21-26. [Google Scholar] [CrossRef] [PubMed]
|
|
[23]
|
Bouameur, J.E., Favre, B. and Borradori, L. (2014) Plakins, a Versatile Family of Cytolinkers: Roles in Skin Integrity and in Human Diseases. Journal of Investigative Dermatology, 134, 885-894. [Google Scholar] [CrossRef] [PubMed]
|
|
[24]
|
Kuga, T., Kume, H., Kawasaki, N., et al. (2013) A Novel Mechanism of Keratin Cytoskeleton Organization through Casein Kinase Ialpha and FAM83H in Colorectal Cancer. Journal of Cell Science, 126, 4721-4731. [Google Scholar] [CrossRef] [PubMed]
|
|
[25]
|
Kayser, J., Haslbeck, M., Dempfle, L., et al. (2013) The Small Heat Shock Protein Hsp27 Affects Assembly Dynamics and Structure of Keratin Intermediate Filament Networks. Biophysical Jour-nal, 105, 1778-1785. [Google Scholar] [CrossRef] [PubMed]
|
|
[26]
|
Toivola, D.M., Strnad, P., Habtezion, A. and Omary, M.B. (2010) Intermediate Filaments Take the Heat as Stress Proteins. Trends in Cell Biology, 20, 79-91. [Google Scholar] [CrossRef] [PubMed]
|
|
[27]
|
Weerasinghe, S.V., Ku, N.O., Altshuler, P.J., Kwan, R. and Omary, M.B. (2014) Mutation of Caspase-Digestion Sites in Keratin 18 Interferes with Filament Reorganization, and Predisposes to Hepatocyte Necrosis and Loss of Membrane Integrity. Journal of Cell Science, 127, 1464-1475. [Google Scholar] [CrossRef] [PubMed]
|
|
[28]
|
Cao, L., Chang, H., Shi, X., Peng, C. and He, Y. (2016) Keratin Mediates the Recognition of Apoptotic and Necrotic Cells through Dendritic Cell Receptor DEC205/CD205. Proceedings of the National Academy of Sciences of the United States of America, 113, 13438-13443. [Google Scholar] [CrossRef] [PubMed]
|
|
[29]
|
Cheng, F. and Eriksson, J.E. (2016) Intermediate Filaments and the Regulation of Cell Motility during Regeneration and Wound Healing. Cold Spring Harbor Perspectives in Biology, 9, a022046. [Google Scholar] [CrossRef] [PubMed]
|
|
[30]
|
Chung, B.M., Arutyunov, A., Ilagan, E., Yao, N., Wills-Karp, M. and Coulombe, P.A. (2015) Regulation of C-X-C Chemokine Gene Expression by Keratin 17 and hnRNP K in Skin Tumor Keratinocytes. Journal of Cell Biology, 208, 613-627. [Google Scholar] [CrossRef] [PubMed]
|
|
[31]
|
Hobbs, R.P., DePianto, D.J., Jacob, J.T., Han, M.C., Chung, B.M., Batazzi, A.S., Poll, B.G., Guo, Y., Han, J., Ong, S., et al. (2015) Keratin-Dependent Regulation of Aire and Gene Expression in Skin Tumor Keratinocytes. Nature Genetics, 47, 933-938. [Google Scholar] [CrossRef] [PubMed]
|
|
[32]
|
Toivola, D.M., Habtezion, A., Misiorek, J.O., et al. (2015) Absence of Keratin 8 or 18 Promotes Antimitochondrial Autoantibody Formation in Aging Male Mice. The FASEB Journal, 29, 5081-5089. [Google Scholar] [CrossRef] [PubMed]
|
|
[33]
|
Chan, J.K.L., Yuen, D., Too, P.H., et al. (2018) Keratin 6a Reorganiza-tion for Ubiquitin-Proteasomal Processing Is a Direct Antimicrobial Response. Journal of Cell Biology, 217, 731-744. [Google Scholar] [CrossRef] [PubMed]
|
|
[34]
|
Rotty, J.D. and Coulombe, P.A. (2012) A Wound-Induced Keratin In-hibits Src Activity during Keratinocyte Migration and Tissue Repair. Journal of Cell Biology, 197, 381-389. [Google Scholar] [CrossRef] [PubMed]
|
|
[35]
|
Helenius, T.O., Misiorek, J.O., Nystrom, J.H., et al. (2015) Keratin 8 Absence Down-Regulates Colonocyte HMGCS2 and Modulates Colonic Ketogenesis and Energy Metabolism. Molecu-lar Biology of the Cell, 26, 2298-2310. [Google Scholar] [CrossRef]
|
|
[36]
|
Alam, C.M., Silvander, J.S., Daniel, E.N., et al. (2013) Keratin 8 Modulates Beta-Cell Stress Responses and Normoglycaemia. Journal of Cell Science, 126, 5635-5644. [Google Scholar] [CrossRef] [PubMed]
|
|
[37]
|
Kerns, M.L., Hakim, J.M., Lu, R.G., et al. (2016) Oxidative Stress and Dysfunctional NRF2 Underlie Pachyonychia Congenita Phenotypes. Journal of Clinical Investigation, 126, 2356-2366. [Google Scholar] [CrossRef]
|
|
[38]
|
Karantza, V. (2011) Keratins in Health and Cancer: More than Mere Epithe-lial Cell Markers. Oncogene, 30, 127-138. [Google Scholar] [CrossRef] [PubMed]
|
|
[39]
|
Stefan, W., Laura, K. and Klaus, P. (2019) Epithelial Keratins: Biology and Implications as Diagnostic Markers for Liquid Biopsies. Molecular Aspects of Medicine, 72, Article ID: 100817. [Google Scholar] [CrossRef] [PubMed]
|
|
[40]
|
Cristofanilli, M., Pierga, J.Y., Reuben, J., et al. (2019) The Clinical Use of Circulating Tumor Cells (CTCs) Enumeration for Staging of Metastatic Breast Cancer (MBC): International Ex-pert Consensus Paper. Critical Reviews in Oncology/Hematology, 134, 39-45. [Google Scholar] [CrossRef] [PubMed]
|
|
[41]
|
Effenberger, K.E., Schroeder, C. and Hanssen, A. (2018) Im-proved Risk Stratification by Circulating Tumor Cell Counts in Pancreatic Cancer. Clinical Cancer Research, 24, 2844-2850. [Google Scholar] [CrossRef]
|
|
[42]
|
Hille, C. and Pantel, K. (2018) Prostate Cancer: Circulating Tumour Cells in Prostate Cancer. Nature Reviews Urology, 15, 265-266. [Google Scholar] [CrossRef] [PubMed]
|
|
[43]
|
Chu, P.G. and Weiss, L.M. (2002) Keratin Expression in Human Tis-sues and Neoplasms. Histopathology, 40, 403-439. [Google Scholar] [CrossRef] [PubMed]
|
|
[44]
|
Bednarz-Knoll, N., Alix-Panabieres, C. and Pantel, K. (2011) Clinical Relevance and Biology of Circulating Tumor Cells. Breast Cancer Research, 13, 228. [Google Scholar] [CrossRef] [PubMed]
|
|
[45]
|
Sharma, P., Alsharif, S., Fallatah, A. and Chung, B.M. (2019) Intermediate Filaments as Effectors of Cancer Development and Metastasis: A Focus on Keratins, Vimentin, and Nestin. Cells, 8, E497. [Google Scholar] [CrossRef] [PubMed]
|
|
[46]
|
Luís, L., Manuel, N., Marta, I.O., et al. (2017) Sialyl-Tn Identifies Muscle-Invasive Bladder Cancer Basal and Luminal Subtypes Facing Decreased Survival, Being Expressed by Circulat-ing Tumor Cells and Metastases. Urologic Oncology: Seminars and Original Investigations, 35, 675.e1-675.e8. [Google Scholar] [CrossRef] [PubMed]
|
|
[47]
|
Heather, S., Annkathrin, H., Sonja, L., et al. (2019) EGFR and HER3 Expression in Circulating Tumor Cells and Tumor Tissue from Non-Small Cell Lung Cancer Patients. Scientific Reports, 9, 7406. [Google Scholar] [CrossRef] [PubMed]
|
|
[48]
|
Antoni, S., Marek, S., Grażyna, D., et al. (2018) CD44+ Cy-tokeratin-Positive Tumor Cells in Blood and Bone Marrow Are Associated with Poor Prognosis of Patients with Gastric Cancer. Gastric Cancer, 22, 264-272. [Google Scholar] [CrossRef] [PubMed]
|
|
[49]
|
Ahn, S.K., Moon, H.G., Ko, E., et al. (2013) Preoperative Serum Tissue Polypeptide-Specific Antigen Is a Valuable Prognostic Marker in Breast Cancer. International Journal of Cancer, 132, 875-881. [Google Scholar] [CrossRef] [PubMed]
|
|
[50]
|
Barak, V., Goike, H., Panaretakis, K.W. and Einarsson, R. (2004) Clinical Utility of Cytokeratins as Tumor Markers. Clinical Biochemistry, 37, 529-540. [Google Scholar] [CrossRef] [PubMed]
|
|
[51]
|
Nanou, A., Coumans, F.A.W., van Dalum, G., et al. (2018) Circulating Tumor Cells, Tumor-Derived Extracellular Vesicles and Plasma Cytokeratins in Castration-Resistant Prostate Cancer Patients. Oncotarget, 9, 19283-19293. [Google Scholar] [CrossRef] [PubMed]
|
|
[52]
|
Michael, N., Julia, S., Annett, M., et al. (2018) Cytokeratin-18 Fragments Predict Treatment Response and Overall Survival in Gastric Cancer in a Randomized Controlled Trial. Tumor Biology, 40, 1-8. [Google Scholar] [CrossRef] [PubMed]
|
|
[53]
|
Holdenrieder, S., Wehnl, B. and Hettwer, K. (2017) Carcinoem-bryonic Antigen and Cytokeratin-19 Fragments for Assessment of Therapy Response in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis. British Journal of Cancer, 116, 1037-1045. [Google Scholar] [CrossRef] [PubMed]
|
|
[54]
|
Clotilde, R., Médéric, L., Jean-Charles, L., et al. (2017) Cancer Biomarker Sensing Using Packaged Plasmonic Optical Fiber Gratings: Towards in Vivo Diagnosis. Biosensors and Bioelectronics, 92,449-456. [Google Scholar] [CrossRef] [PubMed]
|
|
[55]
|
Franziska, H., Claudia, U., Thomas, K., et al. (2019) Identification of Proteomic Markers in Head and Neck Cancer Using MALDI-MS Imaging, LC-MS/MS, and Immunohistochemistry. Proteomics Clinical Applications, 13, Article ID: 1700173. [Google Scholar] [CrossRef] [PubMed]
|