早产儿脑损伤的影响因素研究进展
Research Progress on Influencing Factors of Brain Injury in Premature Infants
DOI: 10.12677/ACM.2022.1281107, PDF,   
作者: 龙 滔, 王 楠, 刑丽媛, 郭甜甜：西安医学院第一附属医院，陕西 西安；屈鹏飞, 李亚军*：西北妇女儿童医院转化医学中心，陕西 西安
关键词: 早产儿脑损伤；缺血缺氧；感染；机械通气；影响因素；Brain Injury in Premature Infants； Ischemia and Hypoxia； Infection； Mechanical Ventilation； Influencing Factors
摘要: 早产儿脑损伤(BIPI)是早产儿主要的并发症之一。尽管随着诊疗水平和围产期护理提高，早产儿存活率明显上升，但BIPI存活者多遗留神经系统后遗症，包括脑瘫、视力、听力及学习障碍等问题。如何避免BIPI的发生和加重、提高远期生存质量成了围产医学和新生儿科工作者关注的重点。本文将BIPI的一些影响因素如缺血缺氧(HI)、高氧、围产期感染、高低碳酸血症、机械通气、糖皮质激素的使用等相关机制作以下综述，为临床围产医学、新生儿科医生治疗和研究BIPI提供参考和思路。
Abstract: Objective Brain injury in premature infants (BIPI) is one of the major complications of premature infants. Although the survival rate of premature infants has improved significantly with the im-provement of diagnosis, treatment and perinatal care, BIPI survivors are often left with neurologi-cal sequelae, including cerebral palsy, vision, hearing and learning disabilities. How to avoid the occurrence and aggravation of BIPI and improve the long-term quality of life has become the focus of perinatal medicine and neonatology workers. In this paper, some influencing factors of BIPI, such as ischemia-hypoxia (HI), hyperoxia, perinatal infection, hypercapnia, hypocapnia, mechanical ven-tilation and the use of glucocorticoids are reviewed as follows, in order to provide reference and ideas for clinical perinatal medicine, neonatologist treatment and research on BIPI.
文章引用：龙滔, 屈鹏飞, 王楠, 刑丽媛, 郭甜甜, 李亚军. 早产儿脑损伤的影响因素研究进展[J]. 临床医学进展, 2022, 12(8): 7674-7682. https://doi.org/10.12677/ACM.2022.1281107

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