益生菌通过肠道菌群治疗功能性便秘的研究进展
Progress of Probiotics in Treating Functional Constipation through Intestinal Flora
DOI: 10.12677/ACM.2023.1351212, PDF,   
作者: 那日娜, 陈 平*：内蒙古医科大学附属医院消化内科，内蒙古 呼和浩特
关键词: 功能性便秘；益生菌；肠道菌群；短链脂肪酸；临床应用；Functional Constipation； Probiotics； Intestinal Flora； Short Chain Fatty Acids； Clinical Application
摘要: 功能性便秘(Functional Constipation, FC)是世界上常见的功能性胃肠疾病之一。FC的发病机制复杂且尚不完全了解，很多研究表明其机制与肠道菌群失调密切相关。因此，治疗上也逐渐关注肠道菌群的平衡。益生菌是肠道微生态制剂，能调节肠道菌群结构以及功能从而影响宿主的健康状态。近年，益生菌对便秘的有益作用已在动物和人群研究中得到了越来越多的证实。但益生菌如何通过肠道菌群缓解功能性便秘的机制没被系统地阐述过，本文就益生菌通过肠道菌群改善功能性便秘的机制进行综述。
Abstract: Functional constipation is one of the common functional gastrointestinal diseases in the world. The pathogenesis of FC is complex and not fully understood. At present, many studies show that its mechanism is closely related to intestinal flora imbalance. Therefore, the treatment has gradually paid attention to the balance of intestinal flora. Probiotics are intestinal microecological agents, which can regulate the structure and function of intestinal flora and affect the health of the host. In recent years, the beneficial effects of probiotics on constipation have been more and more con-firmed in animal and human studies. However, the mechanism of how probiotics can alleviate func-tional constipation through intestinal flora has not been systematically expounded. This paper re-views the mechanism of probiotics improving functional constipation through intestinal flora.
文章引用：那日娜, 陈平. 益生菌通过肠道菌群治疗功能性便秘的研究进展[J]. 临床医学进展, 2023, 13(5): 8669-8674. https://doi.org/10.12677/ACM.2023.1351212

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