久坐行为与心血管疾病和死亡风险的研究进展
Sedentary Behavior and Cardiovascular Disease/Risk of Mortality: A Literature Review
DOI: 10.12677/acm.2024.1441199, PDF,   
作者: 赵 凯, 景兰睿：西安医学院研究生院，陕西 西安
关键词: 久坐行为；心血管疾病；死亡率；Sedentary Behavior； Cardiovascular Disease； Mortality
摘要: 久坐行为(SB)可对人体健康造成损害，特别是心血管系统。随着久坐行为的日益流行，两者之间的关系亟待进一步的探索。本文就久坐行为与心血管疾病和死亡风险进行综述，分析久坐行为在不同程度上对心血管疾病的影响，以及久坐行为如何导致心血管疾病的可能机制，而后讨论了久坐行为对死亡率造成的影响，以期引起人们对于久坐行为危害的重视，推动针对久坐行为制定公共健康指南。
Abstract: Sedentary behavior (SB) poses a threat to human health, particularly the cardiovascular system. As sedentary behavior becomes increasingly prevalent, there is an urgent need for in-depth exploration of their relationship. This article systematically reviews the association between sedentary behavior and the risk of cardiovascular diseases and mortality. It delves into the nuanced impacts of sedentary behavior on varying degrees of cardiovascular diseases, examining potential mechanisms through which sedentary behavior contributes to cardiovascular issues. The discussion extends to scrutinize the influence of sedentary behavior on mortality, aiming to raise awareness of its detrimental effects. The goal is to advocate for the formulation of comprehensive public health guidelines addressing sedentary behavior.
文章引用：赵凯, 景兰睿. 久坐行为与心血管疾病和死亡风险的研究进展[J]. 临床医学进展, 2024, 14(4): 1612-1620. https://doi.org/10.12677/acm.2024.1441199

参考文献

[1] Zang, J. and Ng, S.W. (2016) Age, Period and Cohort Effects on Adult Physical Activity Levels from 1991 to 2011 in China. International Journal of Behavioral Nutrition and Physical Activity, 13, Article No. 40. [Google Scholar] [CrossRef] [PubMed]
[2] Hallal, P.C., Andersen, L.B., Bull, F.C., Guthold, R., Haskell, W. and Ekelund, U. (2012) Global Physical Activity Levels: Surveillance Progress, Pitfalls, and Prospects. The Lancet (London, England), 380, 247-257. [Google Scholar] [CrossRef] 
[3] Matthews, C.E., Chen, K.Y., Freedson, P.S., Buchowski, M.S., Beech, B.M., Pate, R.R., et al. (2008) Amount of Time Spent in Sedentary Behaviors in the United States, 2003-2004. American Journal of Epidemiology, 167, 875-881. [Google Scholar] [CrossRef] [PubMed]
[4] Peters, T.M., Moore, S.C., Xiang, Y.B., Yang, G., Shu, X.O., Ekelund, U., et al. (2010) Accelerometer-Measured Physical Activity in Chinese Adults. American Journal of Preventive Medicine, 38, 583-591. [Google Scholar] [CrossRef] [PubMed]
[5] Bauman, A., Ainsworth, B.E., Sallis, J.F., Hagstromer, M., Craig, C.L., Bull, F.C., et al. (2011) The Descriptive Epidemiology of Sitting. A 20-Country Comparison Using the International Physical Activity Questionnaire (IPAQ). American Journal of Preventive Medicine, 41, 228-235. [Google Scholar] [CrossRef] [PubMed]
[6] 刘利沙. 久坐对女研究生群体体成分与运动能力的影响[D]: [硕士学位论文]. 西安: 陕西师范大学, 2016.
[7] 史穆然. 久坐、运动与中医体质的关系研究[D]: [硕士学位论文]. 北京: 北京中医药大学, 2019.
[8] Guo, C., Zhou, Q., Zhang, D., Qin, P., Li, Q., Tian, G., et al. (2020) Association of Total Sedentary Behaviour and Television Viewing with Risk of Overweight/Obesity, Type 2 Diabetes and Hypertension: A Dose-Response Meta-Analysis. Diabetes, Obesity & Metabolism, 22, 79-90. [Google Scholar] [CrossRef] [PubMed]
[9] Grøntved, A. and Hu, F.B. (2011) Television Viewing and Risk of Type 2 Diabetes, Cardiovascular Disease, and All-Cause Mortality: A Meta-Analysis. JAMA, 305, 2448-2455. [Google Scholar] [CrossRef] [PubMed]
[10] Cong, Y.J., Gan, Y., Sun, H.L., Deng, J., Cao, S.Y., Xu, X., et al. (2014) Association of Sedentary Behaviour with Colon and Rectal Cancer: A Meta-Analysis of Observational Studies. British Journal of Cancer, 11, 817-826. [Google Scholar] [CrossRef] [PubMed]
[11] Patterson, R., McNamara, E., Tainio, M., De Sá, T.H., Smith, A.D., Sharp, S.J., et al. (2018) Sedentary Behaviour and Risk of All-Cause, Cardiovascular and Cancer Mortality, and Incident Type 2 Diabetes: A Systematic Review and Dose Response Meta-Analysis. European Journal of Epidemiology, 33, 811-829. [Google Scholar] [CrossRef] [PubMed]
[12] Biswas, A., Oh, P.I., Faulkner, G.E., Bajaj, R.R., Silver, M.A., Mitchell, M.S., et al. (2015) Sedentary Time and Its Association with Risk for Disease Incidence, Mortality, and Hospitalization in Adults: A Systematic Review and Meta-Analysis. Annals of Internal Medicine, 162, 123-132. [Google Scholar] [CrossRef] 
[13] Ke, J., Li, K., Ke, T., Zhong, X., Zheng, Q., Wang, Y., Li, L., Dai, Y., Dong, Q., Ji, B., Xu, F., Shi, J., Peng, Y., Zhang, Y., Zhao, D. and Wang, W. (2022) Association of Sedentary Time and Carotid Atherosclerotic Plaques in Patients with Type 2 Diabetes. Journal of Diabetes, 14, 64-72. [Google Scholar] [CrossRef] [PubMed]
[14] Tudor-Locke, C., Ainsworth, B.E., Adair, L., Du, S. and Popkin, B. (2003) Physical Activity and Inactivity in Chinese School-Aged Youth: The China Health and Nutrition Survey. International Journal of Obesity, 27, 1093-1099. [Google Scholar] [CrossRef] [PubMed]
[15] Endorsed, B., et al. (2016) Sedentary Behavior and Cardiovascular Morbidity and Mortality: A Science Advisory from the American Heart Association. Circulation, 134, E262-E279. [Google Scholar] [CrossRef] 
[16] Lavie, C.J., Ozemek, C., Carbone, S., Katzmarzyk, P.T. and Blair, S.N. (2019) Sedentary Behavior, Exercise, and Cardiovascular Health. Circulation Research, 124, 799-815. [Google Scholar] [CrossRef] 
[17] Garber, C.E., et al. (2011) American College of Sports Medicine Position Stand. Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Healthy Adults: Guidance for Prescribing Exercise. Medicine & Science in Sports & Exercise, 43, 1334-1359. [Google Scholar] [CrossRef] 
[18] Ekelund, U., Tarp, J., Steene-Johannessen, J., Hansen, B.H., Jefferis, B., Fagerland, M.W., Whincup, P., Diaz, K.M., Hooker, S.P., Chernofsky, A., Larson, M.G., Spartano, N., Vasan, R.S., Dohrn, I.M., Hagströmer, M., Edwardson, C., Yates, T., Shiroma, E., Anderssen, S.A. and Lee, I.M. (2019) Dose-Response Associations between Accelerometry Measured Physical Activity and Sedentary Time and All Cause Mortality: systematic Review and Harmonised Meta-Analysis, 366, l4570. [Google Scholar] [CrossRef] [PubMed]
[19] Matthews, C.E., George, S.M., Moore, S.C., Bowles, H.R., Blair, A., Park, Y., Troiano, R.P., Hollenbeck, A. and Schatzkin, A. (2012) Amount of Time Spent in Sedentary Behaviors and Cause-Specific Mortality in US Adults. The American Journal of Clinical Nutrition, 95, 437-445. [Google Scholar] [CrossRef] [PubMed]
[20] Saunders, T.J., Chaput, J.P. and Tremblay, M.S. (2014) Sedentary Behaviour as an Emerging Risk Factor for Cardiometabolic Diseases in Children and Youth. Canadian Journal of Diabetes, 38, 53-61. [Google Scholar] [CrossRef] [PubMed]
[21] World Health Organization (2010) Global Recommendations on Physical Activity for Health. World Health Organization, Geneva, 58.
[22] Ye, Q., Hong, X., Wang, Z., Qin, Z., Li, C., Lai, Y. and Xu, F. (2018) Joint Associations of Dietary Pattern and Television Viewing with CVD Risk Factors among Urban Men and Women in China: A Cross-Sectional Study. British Journal of Nutrition, 119, 74-82. [Google Scholar] [CrossRef] 
[23] Yu, H. and Schwingel, A. (2018) Associations between Sedentary Behavior, Physical Activity, and Out-of-Pocket Health Care Expenditure: Evidence from Chinese Older Adults. Journal of Aging and Physical Activity, 27, 108-115. [Google Scholar] [CrossRef] [PubMed]
[24] Xu, C.X., Zhu, H.H., Fang, L., Hu, R.Y., Wang, H., Liang, M.B., Zhang, J., Lu, F., He, Q.F. and Wang, L.X. (2017) Gender Disparity in the Associations of Overweight/Obesity with Occupational Activity, Transport to/from Work, Leisure-Time Physical Activity, and Leisure-Time Spent Sitting in Working Adults: A Cross-Sectional Study. Journal of Epidemiology, 27, 401-407. [Google Scholar] [CrossRef] [PubMed]
[25] Zhang, T., Huang, B., Wong, H., Wong, S.Y.-S. and Chung, R.Y.-N. (2022) Built Environment and Physical Activity among Adults in Hong Kong: Role of Public Leisure Facilities and Street Centrality. Land, 11, Article No. 243. [Google Scholar] [CrossRef] 
[26] An, R., Shen, J., Yang, Q. and Yang, Y. (2019) Impact of Built Environment on Physical Activity and Obesity among Children and Adolescents in China: A Narrative Systematic Review. Journal of Sport and Health Science, 8, 153-169. [Google Scholar] [CrossRef] [PubMed]
[27] Cui, Z., Hardy, L.L., Dibley, M.J. and Bauman, A. (2011) Temporal Trends and Recent Correlates in Sedentary Behaviours in Chinese Children. International Journal of Behavioral Nutrition and Physical Activity, 8, Article No. 93. [Google Scholar] [CrossRef] [PubMed]
[28] Billy, G.G., Lemieux, S.K. and Chow, M.X. (2014) Changes in Lumbar Disk Morphology Associated with Prolonged Sitting Assessed by Magnetic Resonance Imaging. PMR, 6, 790-795. [Google Scholar] [CrossRef] [PubMed]
[29] Gobbo, L.A., Júdice, P.B., Hetherington-Rauth, M., Sardinha, L.B. and Dos Santos, V.R. (2020) Sedentary Patterns Are Associated with Bone Mineral Density and Physical Function in Older Adults: Cross-Sectional and Prospective Data. International Journal of Environmental Research and Public Health, 17, 8198. [Google Scholar] [CrossRef] [PubMed]
[30] Bowden Davies, K.A., Sprung, V.S., Norman, J.A., Thompson, A., Mitchell, K.L., Halford, J.C.G., Harrold, J.A., Wilding, J.P.H., Kemp, G.J. and Cuthbertson, D.J. (2018) Short-Term Decreased Physical Activity with Increased Sedentary Behaviour Causes Metabolic Derangements and Altered Body Composition: Effects in Individuals with and without a First-Degree Relative with Type 2 Diabetes. Diabetologia, 61, 1282-1294. [Google Scholar] [CrossRef] [PubMed]
[31] Durrant, J.R., Seals, D.R., Connell, M.L., Russell, M.J., Lawson, B.R., Folian, B.J., Donato, A.J. and Lesniewski, L.A. (2009) Voluntary Wheel Running Restores Endothelial Function in Conduit Arteries of Old Mice: Direct Evidence for Reduced Oxidative Stress, Increased Superoxide Dismutase Activity and Down-Regulation of NADPH Oxidase. The Journal of Physiology, 587, 71-85. [Google Scholar] [CrossRef] [PubMed]
[32] Young, D.R., Hivert, M.-F., Alhassan, S., Camhi, S.M., Ferguson, J.F., Katzmarzyk, P.T., Lewis, C.E., Owen, N., Perry, C.K., Siddique, J., et al. (2016) Sedentary Behavior and Cardiovascular Morbidity and Mortality a Science Advisory from the American Heart Association. Circulation, 134, E262-E279. [Google Scholar] [CrossRef] 
[33] Salmon, J., Bauman, A., Crawford, D., Timperio, A. and Owen, N. (2000) The Association between Television Viewing and Overweight among Australian Adults Participating in Varying Levels of Leisure-Time Physical Activity. International Journal of Obesity and Related Metabolic Disorders, 24, 600-606. [Google Scholar] [CrossRef] [PubMed]
[34] Salmon, J., Owen, N., Crawford, D., Bauman, A. and Sallis, J.F. (2003) Physical Activity and Sedentary Behavior: A Population-Based Study of Barriers, Enjoyment, and Preference. Health Psychology, 22, 178-188. [Google Scholar] [CrossRef] 
[35] Rhodes, R.E., Mark, R.S. and Temmel, C.P. (2012) Adult Sedentary Behavior: A Systematic Review. American Journal of Preventive Medicine, 42, E3-E28. [Google Scholar] [CrossRef] [PubMed]
[36] Buman, M.P., Hekler, E.B., Haskell, W.L., Pruitt, L., Conway, T.L., Cain, K.L., Sallis, J.F., Saelens, B.E., Frank, L.D. and King, A.C. (2010) Objective Light-Intensity Physical Activity Associations with Rated Health in Older Adults. American Journal of Epidemiology, 172, 1155-1165. [Google Scholar] [CrossRef] [PubMed]
[37] Davies, C.A., Vandelanotte, C., Duncan, M.J. and Van Uffelen, J.G. (2012) Associations of Physical Activity and Screen-Time on Health Related Quality of Life in Adults. Preventive Medicine, 55, 46-49. [Google Scholar] [CrossRef] [PubMed]
[38] Schou Andersen, C., Juhl, M., Gamborg, M., Sørensen, T.I. and Nohr, E.A. (2012) Maternal Recreational Exercise during Pregnancy in Relation to Children’s BMI at 7 Years of Age. International Journal of Pediatrics, 2012, Article ID: 920583. [Google Scholar] [CrossRef] [PubMed]
[39] Padmapriya, N., Shen, L., Soh, S.E., Shen, Z., Kwek, K., Godfrey, K.M., Gluckman, P.D., Chong, Y.S., Saw, S.M. and Müller-Riemenschneider, F. (2015) Physical Activity and Sedentary Behavior Patterns before and during Pregnancy in A Multi-Ethnic Sample of Asian Women in Singapore. Maternal and Child Health Journal, 19, 2523-2535. [Google Scholar] [CrossRef] [PubMed]
[40] Hinkley, T., Teychenne, M., Downing, K.L., Ball, K.J. and Hesketh, K.D. (2014) Early Childhood Physical Activity, Sedentary Behaviors and Psychosocial Well-Being: A Systematic Review. Preventive Medicine, 62, 182-192. [Google Scholar] [CrossRef] [PubMed]
[41] LeBlanc, A.G., Spence, J.C., Carson, V., Connor Gorber, S.C., Janssen, I., Kho, M.E., Stearns, J.A., Timmons, B.W. and Tremblay, M.S. (2012) Systematic Review of Sedentary Behaviour and Health Indicators in the Early Years (Aged 0-4 Years). Applied Physiology, Nutrition, and Metabolism, 37, 753-772. [Google Scholar] [CrossRef] [PubMed]
[42] Chu, A.H. and Moy, F.M. (2013) Joint Association of Sitting Time and Physical. Activity with Metabolic Risk Factors among Middle-Aged Malays in a Developing Country: A Cross-Sectional Study. PLOS ONE, 8, E61723. [Google Scholar] [CrossRef] [PubMed]

为你推荐