基本情况

雷博,河南省医学科学院眼科研究所所长,河南省眼科研究所副所长,河南省眼科疾病临床医学研究中心主任,国家眼耳鼻喉疾病临床医学研究中心河南省分中心主任,郑州大学先进医学中心眼科疾病研究中心主任。

 

研究领域

视网膜功能和视网膜疾病诊断及治疗

 

教育背景

2001年 博士后,美国密歇根大学医学院

1997年 博士,以色列技术学院医学院

1989年 硕士,河南医科大学

1986年 学士,河南医科大学医学系

 

工作经历

2017年至今 河南省医学科学院眼科研究所所长、河南省眼科研究所副所长

2009年至2016年 副主任,重庆医科大学附属第一医院、重庆市眼科学重点实验室

2001年至2009年 科学助理教授,美国密苏里大学眼科及视觉

1986年至1993年 眼科主治医师,河南医科大学第一附属医院眼科


论文发表

1. Qin, Chaofan,Yan, Zhengjian,Yu, Qingshuai, et al.Exploring the Relationship Between Immune Cells and Scoliosis by Mendelian Randomization, Colocalization Analysis, and SMR[J].MEDIATORS OF INFLAMMATION,2025,2025(01).DOI:10.1155/mi/8833556.

2. Wang, Xin,Hu, Tao,Qin, Chaofan, et al.Anatomical Importance Between Neural Structure and Bony Landmark in Neuroventral Decompression for Posterior Endoscopic Cervical Discectomy[J].NEUROSPINE,2025,22(01):286-296.DOI:10.14245/ns.2448794.397.

3. Ruiqi Qiu,Mingzhu Yang,Xiuxiu Jin, et al.AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis[J].Neural Regeneration Research,2025,20(08):2408-2419.DOI:10.4103/NRR.NRR-D-23-01301.

4. Zhu, XianJun,Jiang, XiaoYan,Liu, WenJing, et al.Single-cell sequencing analysis reveals the essential role of the m6A reader YTHDF1 in retinal visual function by regulating TULP1 and DHX38 translation[J].ZOOLOGICAL RESEARCH,2025,46(02):429-445.DOI:10.24272/j.issn.2095-8137.2024.399.

5. XianJun Zhu,XiaoYan Jiang,WenJing Liu, et al.Single-cell sequencing analysis reveals the essential role of the m^(6)A reader YTHDF1 in retinal visual function by regulating TULP1 and DHX38 translation[J].Zoological Research,2025,46(02):429-445.DOI:10.24272/j.issn.2095-8137.2024.399.

6. Liu, Jingyang,Guo, Qingge,Liu, Guangming, et al.Immune pathogenic response landscape of acute posterior multifocal placoid pigment epitheliopathy revealed by scRNA sequencing[J].GENES AND IMMUNITY,2025,26(02):75-90.DOI:10.1038/s41435-024-00316-0.

7. Ming, Shuai,Han, Jie,Yao, Xi, et al.Myopia information on TikTok: analysis factors that impact video quality and audience engagement[J].BMC PUBLIC HEALTH,2024,24(01).DOI:10.1186/s12889-024-18687-4.

8. Xu, Jin,Li, Yan,Yao, Shun, et al.Preservation of Mitochondrial Function by SkQ1 in Skin Fibroblasts Derived from Patients with Leber's Hereditary Optic Neuropathy Is Associated with the PINK1/PRKN-Mediated Mitophagy[J].BIOMEDICINES,2024,12(09).DOI:10.3390/biomedicines12092020.

9. Zhu, Yan,Li, ShuYing,Zhang, LuJia, et al.Neuroprotection of the P2X7 receptor antagonist A740003 on retinal ganglion cells in experimental glaucoma[J].NEUROREPORT,2024,35(13):822-831.DOI:10.1097/WNR.0000000000002071.

10. Liu, Qian,Liu, Changgeng,Lei, Bo.siRNA Mediated Downregulation of RhoA Expression Reduces Oxidative Induced Apoptosis in Retinal Ganglion Cells[J].CURRENT MOLECULAR MEDICINE,2024,24(05):630-636.DOI:10.2174/1566524023666230511095628.

11. Jin, Xiuxiu,Guo, Xinyi,Liu, Jingyang, et al.Smart contact lens with transparent MXene decoration for ocular photothermal therapy and eye protection[J].CELL REPORTS PHYSICAL SCIENCE,2023,4(02).DOI:10.1016/j.xcrp.2023.101286.

12. Guo, Xiaohong,Lei, Bo.Choroidal Caverns in a Cohort of Patients with High Myopia[J].INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE,2023,64(09).

13. Zhang, Shuang,Cui, Qianwei,Yang, Shangying, et al.Exome and genome sequencing to unravel the precise breakpoints of partial trisomy 6q and partial Monosomy 2q[J].BMC PEDIATRICS,2023,23(01).DOI:10.1186/s12887-023-04368-5.

14. Zhou, ZhiXin,Xu, LinJie,Wang, HongNing, et al.EphA4/ephrinA3 reverse signaling mediated downregulation of glutamate transporter GLAST in Muller cells in an experimental glaucoma model[J].GLIA,2023,71(03):720-741.DOI:10.1002/glia.24307.

15. Zhao, GuoLi,Zhou, Hong,Guo, YunHui, et al.Modulation of Rac1/PAK1/connexin43-mediated ATP release from astrocytes contributes to retinal ganglion cell survival in experimental glaucoma[J].GLIA,2023,71(06):1502-1521.DOI:10.1002/glia.24354.

16. Liu, Zhenhui,Guo, Ju,Pan, Meng, et al.The genetic spectrum and clinical features of X-linked juvenile retinoschisis in Central China[J].OPHTHALMIC GENETICS,2023,44(03):262-270.DOI:10.1080/13816810.2023.2182328.