基本情况

窦德强,辽宁中医药大学药学院教授、博士生导师。

 

研究领域

中药活性成分及新药研发、中药活性成分的结构修饰及转化

 

工作经历

200510月至今          教授,辽宁中医药大学生药学教研室
200012月至200510月  副教授、硕士生导师,沈阳药科大学天然药化教研室 

20024月至20034月    博士后,美国新泽西州立大学药学部
2001
4月至20023月    博士后,日本名城大学药学部

论文发表

  1. 刘淼,常禹,胡远满,陈宏伟,窦德强,康廷国,许亮,基于LOGISTIC回归的中国牛蒡子资源分布,辽宁中医药大学学报201012(2):15-18
  2. 刘杨楠,窦德强,谢彩香,康廷国,许亮,基于TCMGIS的牛蒡子适宜产区研究,中国现代中药200911(11):11-13
  3. 姚欣,常禹,刘淼,胡远满,陈宏伟,窦德强,康廷国,许亮,道地药材牛蒡子特性与生态因子的关系,湖南农业科学2009(11):18-21
  4. 常禹,刘淼,陈宏伟,胡远满,窦德强,康廷国,许亮,杜天明,道地药材牛蒡子适宜产区划分,辽宁中医药大学学,200911(11):9-12
  5. 周凌,孙兆姝,曹爱民,窦德强,康廷国,正交设计法对二妙胶囊醇提取工艺的研究,中华中医药学刊200927(9):1087-1088
  6. 潘华奇,张淼,刘丽,王楠,胡江春*,窦德强,王书锦,牛蒡根际土壤致害菌Fusarium solani分离鉴定,生物技术,200919(6)46-50
  7. 郭锐,常禹,布仁仓,刘淼,陈宏伟,窦德强,康廷国,许亮,2009,中药材牛蒡子的适宜环境范围确定,科学研究月刊,2009359-62
  8. 李宗梅,李秀珍,常禹,刘淼,胡远满,陈宏伟,窦德强,康廷国,许亮,利用GIS分析中药材牛蒡子的生态适宜性,世界科学技术一中医药现代化和中药研究,200911(3):428-433
  9. 许亮,窦德强,康廷国,吕智,关牛蒡不同居群植物生物多样性及主要伴生种分析,中华中医药学刊200927(9):1860-1862
  10. 窦德强,徐为群,康廷国,张剑峰,中药学专业双语教学方法探讨,高等教育研究200917(9):58-59
  11. 康凯,窦德强,许亮,刘阳楠,康廷国,牛蒡子炮制前后HPLC指纹图谱及牛蒡苷含量比较,中国现代中药 200911(10):22-25
  12. Xiang Zheng, He Fan, Kang Ting-Guo, Dou DeQiang, Gai Kuo, Shi YuYuan, Kim Young Ho, Shi YuYuan. Anti-diabetes Constituents in Leaves of Smallanthus sonchifolius. Natural Products Communications 2010, 5(1): 95-98
  13. De-Qiang Dou, Fang Tian, Ying-Kun Qiu, Zheng Xiang, Bi Xia Xu, Ting Guo Kang, Feng Dong. Studies on chemical constituents of the leaves of Smallantus sonchifolius (yacon): Structures of two new diterpenes. Natural Product Research 2010, 24(1): 40-47
  14. Hongwei Fu, Ying Guo, Wei Li, Deqiang Dou, Tingguo Kang, Kazuo Koike. A new angeloylated triterpenoid saponin from the husks of Xanthoceras sorbifolia Bunge. J of Natural Medicine 2010, 6480-84
  15. Dou De-Qiang, Kang Ting-Guo, Xu Liang, Xie Cai-Xiang, Chang Yu, Lv Zhi, Kang Kai, Liu YN. Ecological suitability of Arctium lappa L and its suitable cultivation regions in China. Planta Medica 2009, 75(4): 420
  16. Haiying Z, Jinpeng H, Xiang Z, Bohao Z, Ying H, Gang L, Deqiang D, et al. Ginsenoside RK3 Inhibits Glioblastoma by Modulating Macrophage M2 Polarization Via the PPARG/CCL2 Axis[J], PHYTOMEDICINE, 2025, 136

Wenjuan H, Yanping X, Hefei X, Yanchang H, Yutong H, Wenxiao M, Yanyun Y, Tingguo K, Deqiang D, Han Z, Liang X, et al. Exploring the Diversity and Potential Functional Characteristics of Microbiota Associated with Different Compartments of Schisandra Chinensis[J], FRONTIERS IN MICROBIOLOGY, 2024, 15

5. Youran Zhang, Ye Huang, Deqiang Dou. Anti-prostate Cancer Mechanism of Black Ginseng During the "nine Steaming and Nine Sun-Drying" Process Based on HPLC Analysis Combined with Vector Space Network Pharmacology.[J], Discover Oncology, 2024, 15(1)

6. Linlin L, Xueying H, Guoshun S, Li F, Deqiang D, et al. Mechanism Difference of Ginseng Medicines with Different Natures on Hyperthyroidism.[J], JOURNAL OF ETHNOPHARMACOLOGY, 2024, 319

7. Linlin L, Mozhu J, Xueying H, Deqiang D, et al. Identifying Biomarkers of Ginseng Medicines with Different Natures on Heart Failure[J], JOURNAL OF ETHNOPHARMACOLOGY, 2024, 329

8. Yumeng W, Chunyan M, Islam A E, Deqiang D, et al. Appearance and Chemical Characteristics of Seeds of Radish with Different Skin Colors[J], Pharmacognosy magazine, 2024, 20(3): 764-772.

9. Xue-Ting Z, De-Qiang D, Yang Q, Guo-Gang Z, et al. Structure Elucidation and NMR Spectral Assignments of One New Dammarane-Type Triterpenoid Saponin from Black Ginseng.[J], Journal of Asian natural products research, 2024, 26(5): 636-643.

10. Xinyue J, Yuchao Y, Huali Y, Maosheng C, Deqiang D, Yang L, et al. Design, Synthesis and Activity Evaluation of Arctigenin Derivatives with HDAC Inhibition Activity[J], RSC Advances, 2024, 14(13): 9314-9325.

11. 万美钰,刘琳琳,曲扬,侯文彬,郭娜 & 窦德强.(2023).黑参的化学成分及药理作用研究进展与展望.沈阳药科大学学报,40(04),518-528+538.DOI:10.14066/j.cnki.cn21-1349/r.2021.0880.

12. 王欣欣,陈小艳,李思佳,张文莲,贾建新 & 窦德强.(2023).中药外治法治疗压疮疗效的Meta分析.包头医学院学报,39(06),83-87.DOI:10.16833/j.cnki.jbmc.2023.06.017.

13. 万美钰 & 窦德强.(2023).基于网络药理学探究人参、红参与黑参治疗气虚的药效物质基础与机制.人参研究,35(03),2-8.DOI:10.19403/j.cnki.1671-1521.2023.03.001.

14. 曲扬,许枬,王丽娜,窦德强,冉小库&才谦.(2023).基于中药化学及天然药物化学课程形成性评价体系的学生学习能力可视化评价研究.中国高等医学教育,(09),64-66.DOI:10.3969/j.issn.1002-1701.2023.09.025.

15. Youran Zhang, Ye Huang, Deqiang Dou. Anti-prostate cancer mechanism of black ginseng during the "Nine Steaming and Nine Sun-Drying" process based on HPLC analysis combined with vector space network pharmacology[J], Research Square (Research Square), 2023

16. Ye Huang, Xiaoku Ran, Deqiang Dou. Anti-prostate Cancer Components of Black Ginseng Based on the "nine Steaming and Nine Sun-Drying" Process[J], PROCESS BIOCHEMISTRY, 2023, 134: 269-275.

17. Hong X, Xi C, Xinlei L, Deqiang D, Zhili X, et al. Schisandrin A Suppresses Inflammation in DSS-induced IBD Mice and H2O2-induced MODE-K Cells Through Wnt/β-Catenin Signaling[J], PHARMACOGNOSY MAGAZINE, 2023, 19(3): 667-677.

18. Nneka A A, Makhotso L, Dou D, Adeyemi O A, et al. Antidepressant Effects of Coumarins and Their Derivatives: A Critical Analysis of Research Advances.[J], European journal of pharmacology, 2023, 956

19.Mo-zhu JIN, Lin-lin LIU, De-qiang DOU. Quantitative Analysis of Steroid Hormones to Explore the Effects of Ginseng Medicines Base on UPLC-QqQ-MS/MS[J], Zhipu Xuebao, 2024, 45(4): 540-551.

20.Mei S, Keke L, Yuanpei Z, Jiwen L, Deqiang D, Xiaojie G, Zhongyu L, et al. Optimization of the Homogenization Process of Ginseng Superfine Powder to Improve Its Powder Characteristics and Bioavailability[J], FOODS, 2024, 13(20)