基本情况

刘广绪，浙江大学动物科学学院副教授、博士生导师。浙江省海洋水产养殖研究所客座研究员，加拿大生态与进化协会会员，中国贝类学会会员。

 

研究领域

海洋贝类受精动力学、近岸水域环境生态学

 

教育背景

2004年9月至2009年5月 博士，加拿大纽芬兰纪念大学，生命科学学院

2001年9月至2004年7月 硕士，中国海洋大学海洋生命学院

1997年9月至2001年7月 学士，中国海洋大学海洋生命学院

 

工作经历

2009年5月至2011年12月 助理研究员，浙江大学动物科学学院

2009年5月至2011年12月 副教授，博导，浙江大学动物科学学院


科研项目

  1. 2018-2022国家重点研发计划“蓝色粮仓科技创新”重点专项课题“酸化等多重环境胁迫对养殖生物生存和生理的影响与生态效应研究”（NO. 2018YFD0900603）。2022-2025国家自然科学基金面上项目“抗抑郁药氟西汀对泥蚶受精的影响及其作用机理研究”（NO. 32172944）。
  2. 2024-2026浙江省自然科学基金重点项目“海洋工程打桩噪音损害泥蚶免疫应答的作用机制研究”（NO. LZ24D060001）。
  3. 2021-2025浙江省农业新品种选育重大科技专项“缢蛏、泥蚶速生、抗逆新品种培育与示范”子课题（2021C02069-7）。
  4. 2021-2023浙江省重点研发计划项目“重要渔业水域生态容量评估及生态修复关键技术-山塘水库和池塘渔业养殖生态容量评估及生态修复关键技术”子课题（2021C02048-006）。
  5. 2017-2020国家自然科学基金面上项目“海洋酸化对泥蚶多精受精影响的机理研究”（NO. 31672634）。


论文发表

  1. Kuankuan Yuan#, Yingying Yu#, Yujie Liu, Xiulin Yang, Yanhang Mo, Wei Shi, Guangxu Liu*, Hongye Li, Weidong Yang*. Microplastics-exposure experience aggravates the accumulation of diarrhetic shellfish toxins (DSTs) in thick-shell mussel Mytilus coruscus through impairing detoxification processes. Journal of Hazardous Materials, 2025, 484: 136782. DOI: https://doi.org/10.1016/j.jhazmat.2024.136782. IF5=12.2.
  2. Yang Shu, Weishang Zhou, Weixia Zhang, Lingzheng Lu, Yan Gao, Yingying Yu, Conghui Shan, Difei Tong, Xunyi Zhang, Wei Shi, Guangxu Liu*. Exposure to malathion impairs learning and memory of zebrafish by disrupting cholinergic signal transmission, undermining synaptic plasticity, and aggravating neuronal apoptosis. Journal of Hazardous Materials, 2025, 488: 137391. DOI: https://doi.org/10.1016/j.jhazmat.2025.137391. IF5=12.2.
  3. Difei Tong, Yingying Yu, Lingzheng Lu, Weishang Zhou, Yihan Yu, Xunyi Zhang, Dandan Tian, Guangxu Liu, Wei Shi*. Microplastics weaken the exoskeletal mechanical properties of Pacific whiteleg shrimp Litopenaeus vannamei. Journal of Hazardous Materials, 2024, 468: 133771. DOI: https://doi.org/10.1016/j.jhazmat.2024.133771. IF5=12.2.
  4. Dandan Tian, Weixia Zhang, Lingzheng Lu, Yihan Yu, Yingying Yu, Xunyi Zhang, Weifeng Li, Wei Shi, Guangxu Liu*. Enrofloxacin exposure undermines gut health and disrupts neurotransmitters along the microbiota-gut-brain axis in zebrafish. Chemosphere, 2024, 356: 141971. DOI: https://doi.org/10.1016/j.chemosphere.2024.141971. 
  5. Kuankuan Yuan, Yingying Yu, Yanhang Mo, Yujie Liu, Weixia Zhang, Jinjin Lv, Wei Shi, Guangxu Liu*, Hongye Li, Weidong Yang. Exposure to microplastics renders immunity of the thick-shell mussel more vulnerable to diarrhetic shellfish toxin-producing harmful algae. Science of the Total Environment, 2024, 926: 172125. DOI: https://doi.org/10.1016/j.scitotenv.2024.172125. IF5=8.2.
  6. Yu Han, Weixia Zhang, Yu Tang, Wei Shi, Zhiquan Liu, Imane Lamine, Hangjun Zhang, Jing Liu, Guangxu Liu*. Triclosan exposure induces immunotoxic impacts by disrupting the immunometabolism, detoxification, and cellular homeostasis in blood clam (Tegillarca granosa). Aquatic Toxicology, 2024, 266: 106778. DOI: https://doi.org/10.1016/j.aquatox.2023.106778. IF5=4.1.
  7. Jindian Liu, Lingzheng Lu, Hongjian Song, Shuai Liu, Guangxu Liu, Bao Lou, Wei Shi*. Effects of triclosan on lipid metabolism and underlying mechanisms in the cyprinid fish Squalidus argentatus. Science of the Total Environment, 2024, 951: 175627. DOI: https://doi.org/10.1016/j.scitotenv.2024.175627. IF5=8.2.
  8. Lingzheng Lu, Conghui Shan, Difei Tong, Yingying Yu, Weixia Zhang, Xunyi Zhang, Yang Shu, Weifeng Li, Guangxu Liu, Wei Shi*. Olfactory toxicity of tetrabromobisphenol A to the goldfish Carassius auratus. Journal of Hazardous Materials, 2024, 479: 135661. DOI: https://doi.org/10.1016/j.jhazmat.2024.135661. IF5=12.2.
  9. Weixia Zhang, Yu Tang, Yu Han, Dandan Tian, Yihan Yu, Yingying Yu, Weifeng Li, Wei Shi, Guangxu Liu*. Pentachlorophenol impairs the antimicrobic capability of blood clam via undermining humoral immunity and disrupting humoral-cellular crosstalk. Chemosphere, 2024, 364: 143230. DOI: https://doi.org/10.1016/j.chemosphere.2024.143230.
  10. Weixia Zhang, Dandan Tian, Yihan Yu, Difei Tong, Weishang Zhou, Yingying Yu, Lingzheng Lu, Weifeng Li, Guangxu Liu*, Wei Shi*. Micro/nanoplastics impair the feeding of goldfish by disrupting the complicated peripheral and central regulation of appetite. Science of the Total Environment, 2024, 946: 174112. DOI: https://doi.org/10.1016/j.scitotenv.2024.174112. IF5=8.2.
  11. Dandan Tian, Yihan Yu, Lingzheng Lu, Difei Tong, Weixia Zhang, Xunyi Zhang, Wei Shi*, Guangxu Liu*. Tris(2-chloroethyl) phosphate exerts hepatotoxic impacts on zebrafish by disrupting hypothalamic-pituitary-thyroid and gut-liver axes. Environmental Science & Technology, 2023, DOI: https://doi.org/10.1021/acs.est.3c01631. IF5=12.154.
  12. Lin Huang, Guangxu Liu*, Yingchun Fu*. Recent developments in biosensing strategies for the detection of small molecular contaminants to ensure food safety in aquaculture and fisheries. Trends in Food Science & Technology, 2023, 133: 15-27. IF5=17.835.
  13. Weishang Zhou, Wei Shi, Xueying Du, Yu Han, Yu Tang, Sanghyok Ri, Kwangjin Ju, Tongchol Kim, Lin Huang, Weixia Zhang, Yihan Yu, Dandan Tian, Yingying Yu, Liangbiao Chen, Zhichao Wu, Guangxu Liu*. Assessment of non-alcoholic fatty liver disease symptoms and gut-liver axis status in zebrafish after exposure to polystyrene microplastics and oxytetracycline, alone and in combination. Environmental Health Perspectives, 2023, DOI: https://doi.org/10.1289/EHP11600. IF5=11.720.
  14. Lin Huang, Weixia Zhang, Difei Tong, Lingzheng Lu, Weishang Zhou, Dandan Tian, Guangxu Liu, Wei Shi*. Triclosan and triclocarban weaken the olfactory capacity of goldfish by constraining odorant recognition, disrupting olfactory signal transduction and disturbing olfactory information processing. Water Research, 2023, DOI: https://doi.org/10.1016/j.watres.2023.119736. IF5=13.847.
  15. Weishang Zhou, Difei Tong, Dandan Tian, Yingying Yu, Lin Huang, Weixia Zhang, Yihan Yu, Lingzheng Lu, Xunyi Zhang, Wangqi Pan, Jiawei Shen, Wei Shi, Guangxu Liu*. Exposure to polystyrene nanoplastics led to learning and memory deficits in zebrafish by inducing oxidative damage and aggravating brain aging. Advanced Healthcare Materials, 2023, DOI: https://doi.org/10.1002/adhm.202301799. IF5=10.6.
  16. Lin Huang, Weixia Zhang, Weishang Zhou, Liangbiao Chen, Guangxu Liu*, Wei Shi*. Behaviour, a potential bioindicators for toxicity analysis of waterborne microplastics: A review. Trends in Analytical Chemistry, 2023, DOI: https://doi.org/10.1016/j.trac.2023.117044. IF5=13.405.
  17. Yihan Yu, Lihua Hu, Dandan Tian, Yingying Yu, Lingzheng Lu, Jiongming Zhang, Xianke Huang, Maocang Yan, Liangbiao Chen, Wei Shi, Guangxu Liu*. Toxicities of polystyrene microplastics (MPs) and hexabromocyclododecane (HBCD), alone or in combination, to the hepatopancreas of the whiteleg shrimp, Litopenaeus vannamei. Environmental Pollution, 2023, DOI: https://doi.org/10.1016/j.envpol.2023.121646. IF5=10.366.