基本情况

许文涛，中国农业大学营养与健康系教授，博士生导师。入选国家级高层次人才计划、“农业农村部专项人才计划青年英才”、教育部“新世纪优秀人才”、北京市科技新星、中国农业大学“人才培育发展支持计划”领军教授B类、青年新星A类并组建“功能核酸与营养健康”青年科学家创新团队。农业农村部农业转基因生物安全评价（食用）重点实验室副主任、农业农村部农产品贮藏保鲜质量安全风险评估实验室（北京）副主任、担任农业农村部农产品质量监督检验测试中心（北京）副主任、国家乳业技术创新中心技术委员会委员。连续入选爱思唯尔“全球前2%顶尖科学家”。



研究领域

  1. 功能核酸（筛选裁剪、生物传感、生物材料、纳米营养及药物靶向）
  2. 功能食品（配方开发、机制挖掘、精准营养及功效评价、名特优新高值化产品开发）
  3. 安全评价（农业生物技术及合成生物学产品分子特征及安全评价、安全风险因子精准检测及精准毒理机制解析）



科研项目

  1. 国家自然基金面上项目“乳品中金黄色葡萄球菌及其肠毒素的功能核酸分子识别机制解析及可视化共检技术开发”（2023-2027）主持
  2. 国家重点研发计划课题“动物源性产品中多类别有害物无损共检技术及装置研发”（2022-2026）主持
  3. 国家自然基金重大仪器专项“单细胞代谢毒理学效应超灵敏精准质谱分析装置研制”（2020-2024）子课题主持
  4. 国家自然基金面上项目“基于复合纳米材料的食源性致病微生物超灵敏等温核酸生物传感器及智能定量装备的研究”（2019-2022）主持
  5. 转基因专项“转基因产品现场快速检测仪器设备研发”（2018-2020）主持
  6. 北京市科技计划项目“肉类预制调理和植物基新兴食品安全风险防控技术研究及示范应用”（2022-2025）主持
  7. 国家科技重大专项“科技创新2030-农业生物育种，基因编辑牛分子特征识别及非预期效应评估技术”（2022-2023）主持
  8. 北京市科技新星计划“功能核酸纳米精准营养平台的搭建及抗皮肤衰老的研究”（2023-2026）主持



教材专著

  1. 功能核酸, 许文涛，2024，中国轻工业出版社.
  2. 功能核酸生物传感器-理论篇, 许文涛，2020，科学出版社.
  3. 食品安全检测技术（第3版）, 许文涛.2024，中国农业大学出版社.
  4. 食品安全快速检测, 许文涛，程楠.2023，科学出版社.
  5. 食品安全学, 许文涛，2021，中国林业出版社.



论文发表

  1. Xinxin Wang, Ning Xu, Longjiao Zhu, He Yang, Chen Li, Hongtao Tian*, Wentao Xu*. Structural Antagonism-Aided Conformational Regulation Enables an Aptamer-Loop G-Quadruplex Modular Sensor of β-Lactoglobulin. Small, 2024, 2307995.
  2. Yanger Liu, Yifan Wu, Lei Wang, Longjiao Zhu, Yulan Dong*,Wentao Xu*.A ratiometric dual-fluorescent paper-based synthetic biosensor for visual detection of tetracycline on-site. Journal of Hazardous Materials, 2024, 467, 133647.
  3. Chengyun Wang, Xinyue Lan, Longjiao Zhu, Yanhui Wang, Xinru Gao, Jie Li, Hongtao Tian, Zhihong Liang*, Wentao Xu*. Construction Strategy of Functionalized Liposomes and Multidimensional Application. Small, 2024, 2309031.
  4. Wenping Yang, Longjiao Zhu, Wentao Xu*. Biologically inspired Co-MOF as catalase mimics with an unexpected ROS production ability for the efficient removal of organic dyes. Journal of Environmental Chemical Engineering, 2024, 12, 112358.
  5. Xuan Ma, Yangzi Zhang, Longjiao Zhu, Yifan Wu, Jun Li, Kunlun Huang, Wentao Xu*. Aptamer and Thiol Co-Regulated Color-Shifting Fluorophores via Dynamic Through-Bond/Space Conjugation for Constructing Ratiometric RNA Sensor. Small, 2024, 2401437.
  6. Ziqi Zhou, Xinyue Lan, Longjiao Zhu, Yangzi Zhang, Kehan Chen, Wenqiang Zhang, Wentao Xu*. Portable dual-aptamer microfluidic chip biosensor for Bacillus cereusbased on aptamer tailoring and dumbbell-shaped probes. Journal of Hazardous Materials, 2023, 445, 130545.
  7. Keren Chen, Longjiao Zhu, Zaihui Du, Xinyue Lan, Kunlun Huang, Wenqiang Zhang, Wentao Xu*. Docking-aided Rational Tailoring of a Fluorescence- and Affinity-Enhancing Aptamer for a Label-free Ratiometric Malachite Green Point-of-Care Aptasensor, Journal of Hazardous Materials. 2023, 130798.
  8. Xinyue Lan#, Longjiao Zhu#, Yangzi Zhang, Keren Chen, Jia Wang, Zaihui Du, Shuting Li, Xu Chen, Wentao Xu*. Cavity hairpin ThT-light nucleic acid switches: the construction of label- and enzyme-free sensing and imaging platforms. Nucleic Acids Research, 2023, 51(8): 3556-3572.
  9. Charles Asakiya, Yangzi Zhang, Liye Zhu, Michael Ackah, Samad Tavakoli, Longjiao Zhu, Kunlun Huang, Wentao Xu*.Self-assembled pH-responsive DNA nanosponges for targeted co-delivery of doxorubicin and capsaicin for colorectal cancer therapy. Biochemical Engineering Journal, 2023, 195, 108926.
  10. Zaihui Du, Longjiao Zhu, Pengfei Wang, Xinyue Lan, Shenghao Lin, and Wentao Xu*. Coordination-Driven One-Step Rapid Self-Assembly Synthesis of Dual-Functional Ag@Pt Nanozyme. Small, 2023, 19, 230104
  11. Yangzi Zhang, Longjiao Zhu, Xuan Ma, Siyue Zhu, Yongqiang Ma, Sabir Hussain, Xiaoyun He*, Wentao Xu*. An Effective Docking-Guided Strategy for Rational Tailoring of Fluorescent Aptamer Switches of Dimethylindole Red Analogue. Analytical Chemistry, 2023, 95(18): 7076-7081.
  12. Shuting Li, Longjiao Zhu, Shenghao Lin, Wentao Xu*. Toehold-mediated biosensors: Types, mechanisms and biosensing strategies. Biosensors and Bioelectronics, 2023, 220, 114922.
  13. Min Yang, Longjiao Zhu, Wenping Yang, Wentao Xu*.Nucleic acid-templated silver nanoclusters: A review of structures, properties, and biosensing applications. Coordination Chemistry Reviews. 2023, 491, 215247.