基本情况

董军,苏州大学三级教授,博士生导师,博士后合作导师,附属第二医院神经外科主任医师、科副主任、苏州大学微创神经外科研究所副所长。1996年毕业于哈尔滨医科大学临床医学七年制专业,1999年获苏州医学院神经外科学博士学位,同年分配至苏州大学附属第二医院神经外科工作至今。多次赴美国、德国和日本访学神经外科微创显微手术和神经内镜手术技术,擅长颅脑及脊髓肿瘤手术及神经内镜微创手术,在苏州地区率先开展神经内镜微创手术,开展脑出血、复杂脑积水及垂体瘤内镜微创手术。在重症颅脑外伤救治及出血性脑卒中的外科治疗具有丰富的经验。

 

教育背景

19969月至19997月 神经外科学博士,苏州医学院

19899月至19967月 临床医学硕士(七年制本硕连读),哈尔滨医科大学

 

工作经历

20135月至今     博士生导师,苏州大学

20117月至今     教授,苏州大学

20099月至今     主任医师,苏州大学附属第二医院神经外科

20053月至今     硕士生导师,苏州大学

20039月至20098月 副教授、副主任医师,苏州大学附属第二医院神经外科

19993月至20038月 主治医师、讲师,苏州大学附属第二医院神经外科

 

学术任职

中国医师协会脑胶质瘤专委会第1-3届委员兼分子诊疗学组副组长、中国临床肿瘤学会神经系统肿瘤专家委员会第1-2届常委、中国抗癌协会神经肿瘤专业委员会第6-7届常委、中国医药教育协会第1届神经内镜与微创医学专业委员会副秘书长、欧美同学会医师协会神经肿瘤分会第1-2届委员兼副秘书长、中国人体健康科技促进会第1届神经肿瘤专业委员会常委。

 

荣誉奖励

2021年度人民好医生(神经肿瘤)

2019年度苏州市科技魅力人物

2015年度王忠诚中国神经外科医师奖

 

科研成果

主持国家自然科学基金面上项目5项,通讯作者发表Cell Res, Cancer Lett, JNS, Glia, CDD, ACS NanoSCI论著121篇,授权专利9项。先后获得国防科技进步奖1项,中华医学科技奖2项,江苏省科学技术奖2项。

 

论文发表


  1. Ni F, Lv H, Lin L, Zhang Y, Qiao Y, Zhang X, Li Z, Wang X, Dai X, Dong J. Antitumor/anti-inflammatory effects/tissue healing as an all-in-one therapeutic strategy for nasopharyngeal carcinoma. J Nanobiotechnology. 2025 Jun 9;23(1):431. 
  2. Sun S, Li Y, Zhang G, Zhang Y, Dong J. A randomized controlled Trial of telerehabilitation intervention for acute ischemic stroke patients Post-Discharge. J Clin Neurosci. 2025 Jun;136:111245.
  3. Zhang H, Yang L, Han M, Han Y, Jiang Z, Zheng Q, Dong J, Wang T, Li Z. Boost Infiltration and Activity of T Cells via Inhibiting Ecto-5'-nucleotidase (CD73) Immune Checkpoint to Enhance Glioblastoma Immunotherapy. ACS Nano. 2024 Aug 27;18(34):23001-23013.
  4. Guo J, Wang J, Zhang P, Wen P, Zhang S, Dong X, Dong J. TRIM6 promotes glioma malignant progression by enhancing FOXO3A ubiquitination and degradation. Transl Oncol. 2024 Aug;46:101999.
  5. Li H, Zhu J, Liu X, Liu L, Huang S, Wu A, Xu Z, Zhang X, Li Z, Ni F, Liu L, Dong J. Glioma stem cell-derived exosomes induce the transformation of astrocytes via the miR-3065-5p/DLG2 signaling axis. Glia. 2024 May;72(5):857-871. 
  6. Huang S, Zhang P, Yin N, Xu Z, Liu X, Wu A, Zhang X, Li Z, Zhang Z, Zhong T, Liu L, Shi Y, Dong J. Glioblastoma stem cell-derived exosomal miR-374b-3p promotes tumor angiogenesis and progression through inducing M2 macrophages polarization. iScience. 2024 Feb 22;27(3):109270.
  7. Wen P, Li H, Liu L, Liu X, Xu Z, Dong J. SENP1-Mediated deSUMOylation Regulates the Tumor Remodeling of Glioma Stem Cells Under Hypoxic Stress. Technol Cancer Res Treat. 2024 Jan-Dec;23:15330338241257490.
  8. Liu X, Liu L, Wu A, Huang S, Xu Z, Zhang X, Li Z, Li H, Dong J. Transformed astrocytes confer temozolomide resistance on glioblastoma via delivering ALKBH7 to enhance APNG expression after educating by glioblastoma stem cells-derived exosomes. CNS Neurosci Ther. 2024 Feb;30(2):e14599.
  9. Ma Y, Wang Q, Du S, Luo J, Sun X, Jia B, Ge J, Dong J, Jiang S, Li Z. Multipathway Regulation for Targeted Atherosclerosis Therapy Using Anti-miR-33-Loaded DNA Origami. ACS Nano. 2024 Feb 6. 
  10. Ge Y, Jia B, Zhang P, Chen B, Liu L, Shi Y, Huang S, Liu X, Wang R, Xie Y, Li Z, Dong J. TBX15 facilitates malignant progression of glioma by transcriptional activation of TXDNC5. iScience. 2024 Jan 18;27(2):108950. 
  11. Li S, Yuan J, Cheng Z, Li Y, Cheng S, Liu X, Huang S, Xu Z, Wu A, Liu L, Dong J. Hsa_circ_0021205 enhances lipolysis via regulating miR-195-5p/HSL axis and drives malignant progression of glioblastoma. Cell Death Discov. 2024 Feb 10;10(1):71. 
  12. Xiang Y, Li X, Huang Y, Gao S, Wei P, Wu L, Dong J. ADSCs encapsulated in Gelatin methacrylate substrate promotes the repair of peripheral nerve injury by SIRT6/PGC-1α pathway. Regen Ther. 2024 Aug 30;26:671-682.
  13. Liu L, Zhou X, Cheng S, Ge Y, Chen B, Shi J, Li H, Li S, Li Y, Yuan J, Wu A, Liu X, Huang S, Xu Z, Dong J. RNA-binding protein DHX9 promotes glioma growth and tumor-associated macrophages infiltration via TCF12. CNS Neurosci Ther. 2023 Apr;29(4):988-999. 
  14. Cheng S, Liu L, Wang D, Li Y, Li S, Yuan J, Huang S, Xu Z, Jia B, Li Z, Dong J. Upregulation of the ZNF148/PTX3 axis promotes malignant transformation of dendritic cells in glioma stem-like cells microenvironment. CNS Neurosci Ther. 2023 Sep;29(9):2690-2704.
  15. Chen Z, Zhang Y, Feng S, Yuan J, Shi D, Wang Y, Li Y, Dong J. Prognostic value and immune-infiltration pattern of FOXD3-AS1 in patients with glioma. Front Pharmacol. 2023 Apr 4;14:1162309.
  16. Xu X, Yang Y, Liu Y, Ge X, Yi T, Xie Y, Ning C, Shen S, Sun Z, Zhang Z, Zhai Q, Wang X, Meng X, Dong J, Huang Q, Yang X, Li W, Jin X. Combinatorial Application of Papain and CD66B for Isolating Glioma- Associated Neutrophils. Curr Cancer Drug Targets. 2023;23(5):400-411.
  17. Cheng Z, Li S, Yuan J, Li Y, Cheng S, Huang S, Dong J. HDAC1 mediates epithelial-mesenchymal transition and promotes cancer cell invasion in glioblastoma. Pathol Res Pract. 2023 Jun;246:154481.
  18. Huang S, Liu L, Xu Z, Liu X, Wu A, Zhang X, Li Z, Li S, Li Y, Yuan J, Cheng S, Li H, Dong J. Exosomal miR-6733-5p mediates cross-talk between glioblastoma stem cells and macrophages and promotes glioblastoma multiform progression synergistically. CNS Neurosci Ther. 2023 Dec;29(12):3756-3773.
  19. Liu X, Dai X, Dai C, Zhu Q, Chen A, Chen Y, Chen N, Chen P, Rong R, Shi C, Xiao S, Dong J. Rare adult pilocytic astrocytoma of the septum pellucidum with novel RIN2::BRAF fusion. Virchows Arch. 2023 Feb;482(2):445-450. 
  20. Shi J, Zhang P, Dong X, Yuan J, Li Y, Li S, Cheng S, Ping Y, Dai X, Dong J. METTL3 knockdown promotes temozolomide sensitivity of glioma stem cells via decreasing MGMT and APNG mRNA stability. Cell Death Discov. 2023 Jan 23;9(1):22.