经阴道三维超声联合超声造影对子宫内膜息肉的诊断价值研究

The Diagnostic Value of Transvaginal Three-Dimensional Ultrasound Combined with Contrast-Enhanced Ultrasound in Endometrial Polyps

摘要: 目的：探讨经阴道三维超声(3 dimensional transvaginal ultrasound, 3D-TVS)联合超声造影(contrast-enhanced ultrasound, CEUS)对子宫内膜息肉(Endometrium polyps, EPs)的诊断价值。方法：选取112例临床可疑EPs患者，分别行经阴道超声(2 dimensional transvaginal ultrasound, 2D-TVS)、3D-TVS及CEUS检查，所有患者均行宫腔镜获得病理检查结果。采用SPSS 24.0统计学软件分析，计数资料采用[n(%)]表示，进行交叉检验及ROC曲线分析结果，以p < 0.05为差异有统计学意义。结果：术后病理确定EPs患者共55例，57例为非子宫内膜息肉。2D-TVS诊断EPs准确度为74.0%，敏感度69.1%、特异度78.9%；3D-TVS诊断EPs准确度为77.6%，敏感度74.5%、特异度80.7%；2D-TVS联合CEUS诊断结果为82.1%，敏感度90.9%、特异度84.2%；3D-TVS联合CEUS诊断结果为91.9%，敏感度90.9%、特异度93.0%，差异有统计学意义(p < 0.05)。结论：3D-TVS超声联合CEUS检查在子宫内膜息肉诊断方面具有明显优势。

Abstract: Objective: To investigate the diagnostic value of three-dimensional transvaginal ultrasound(3D-TVS) combined with contrast-enhanced ultrasound (CEUS) in Endometrial polyps (Eps). Methods: A total of 112 patients with clinically suspected EPs were selected and examined by 2-dimensional transvaginal ultrasound (2D-TVS), 3D-TVS and CEUS, respectively. All patients underwent hysteroscopy to obtain pathological examination results. SPSS 24.0 statistical software was used for analysis, and the count data was represented by [n(%)]. Cross-check and ROC curve analysis were performed, and p < 0.05 was considered statistically significant. Results: Postoperative pathology confirmed a total of 55 patients with EPs, 57 of whom were non-endometrial polyps. The accuracy, sensitivity and specificity of 2D-TVS in the diagnosis of EPs were 74.0%, 69.1% and 78.9%. The accuracy, sensitivity and specificity of 3D-TVS for EPs diagnosis were 77.6%, 74.5% and 80.7%. The diagnostic results of 2D-TVS combined with CEUS were 82.1%, sensitivity 90.9%, specificity 84.2%, and those of 3D-TVS combined with CEUS were 91.9%, sensitivity 90.9%, specificity 93.0%, with statistical significance (p < 0.05). Conclusion: 3D-TVS ultrasound combined with CEUS examination has obvious advantages in the diagnosis of endometrial polyps.