基于“阳化气,阴成形”理论从“痰”论治多囊卵巢综合征性不孕症
On the Treatment of Polycystic Ovary Syndrome Infertility from the Perspective of “Phlegm” Based on the Theory of “Yang Transforming Qi and Yin Shaping”
摘要: 多囊卵巢综合征(Polycystic Ovary Syndrome, PCOS)是一种女性常见内分泌疾病,而不孕是PCOS的常见临床表现。脾肾阳虚“阳化气”不足而导致“阴成形”太过形成以痰为核心的病理产物是PCOS不孕症发生的重要原因。基于“阳化气,阴成形”理论治疗PCOS不孕,“阳化气”不足则温肾健脾以治本,“阴成形”太过则化痰袪瘀以治标。本文基于“阳化气,阴成形”理论探讨PCOS不孕症的证治机理,从痰湿、痰瘀、痰郁出发,探讨目前中医对本病的理论研究及治疗现状,为临床治疗PCOS不孕症提供一定的思路与依据。
Abstract: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder in women, and infertility is a common clinical manifestation of PCOS. Deficiency of spleen and kidney Yang, insufficient “Yang transforming qi”, leading to excessive “Yin shaping” and the formation of pathological products centered on phlegm, is an important cause of PCOS infertility. Based on the theory of “Yang transforming qi and Yin shaping”, PCOS infertility is treated. When “Yang transforming qi” is insufficient, the kidney is warmed and the spleen is strengthened to address the root cause; when “Yin shaping” is excessive, phlegm is transformed, and blood stasis is removed to treat the symptoms. This article explores the therapeutic mechanism of PCOS infertility based on the theory of “Yang transforming qi and Yin shaping”. Starting from phlegm-dampness, phlegm-stasis and phlegm-depression, it discusses the current theoretical research and treatment status of this disease in traditional Chinese medicine, providing certain ideas and basis for the clinical treatment of PCOS infertility.
文章引用:杨欣雨, 杨新鸣. 基于“阳化气,阴成形”理论从“痰”论治多囊卵巢综合征性不孕症[J]. 中医学, 2025, 14(7): 3154-3159. https://doi.org/10.12677/tcm.2025.147465

参考文献

[1] Hoeger, K.M., Dokras, A. and Piltonen, T. (2020) Update on PCOS: Consequences, Challenges, and Guiding Treatment. The Journal of Clinical Endocrinology & Metabolism, 106, e1071-e1083. [Google Scholar] [CrossRef] [PubMed]
[2] 黄荷凤, 王波, 朱依敏. 不孕症发生现状及趋势分析[J]. 中国实用妇科与产科杂志, 2013, 29(9): 688-690.
[3] 何虹瑾, 王素霞. 中医药治疗多囊卵巢综合征不孕机制研究进展[J]. 浙江中西医结合杂志, 2023, 33(6): 573-575.
[4] Wang, Y., Ni, Z. and Li, K. (2021) The Prevalence of Anxiety and Depression of Different Severity in Women with Polycystic Ovary Syndrome: A Meta-Analysis. Gynecological Endocrinology, 37, 1072-1078. [Google Scholar] [CrossRef] [PubMed]
[5] Hoeger, K.M., Dokras, A. and Piltonen, T. (2020) Update on PCOS: Consequences, Challenges, and Guiding Treatment. The Journal of Clinical Endocrinology & Metabolism, 106, e1071-e1083. [Google Scholar] [CrossRef] [PubMed]
[6] 刘玉良. 感悟《黄帝内经》“阳化气, 阴成形” [J]. 中华中医药杂志, 2016, 31(12): 5185-5187.
[7] 许博文, 李杰, 高瑞珂, 等. 基于“阳化气, 阴成形”理论探讨肿瘤的中医辨治[J]. 中医杂志, 2020, 61(4): 315-318.
[8] 梁春云, 于红娟. 基于“阳化气, 阴成形”理论探讨温阳化瘀法治疗多囊卵巢综合征[J]. 天津中医药, 2022, 39(2): 228-231.
[9] 孙天琳, 汤玲, 史梅莹, 等. 国医大师肖承悰运用七子益肾理冲汤改善多囊卵巢综合征卵泡发育经验[J]. 世界中医药, 2023, 18(12): 1719-1722.
[10] 郭敏敏, 徐云霞. 徐云霞补肾为要治疗多囊卵巢综合征不孕症经验[J]. 中医药临床杂志, 2020, 32(3): 425-428.
[11] Yang, Y., Zhou, W., Wu, S., Tang, W., Wang, Z., Zhou, Z., et al. (2021) Intestinal Flora Is a Key Factor in Insulin Resistance and Contributes to the Development of Polycystic Ovary Syndrome. Endocrinology, 162, bqab118. [Google Scholar] [CrossRef] [PubMed]
[12] 李秋颖, 周游, 刘一, 等. 中医药调节肠道菌群治疗多囊卵巢综合征研究进展[J]. 辽宁中医药大学学报, 2025, 27(1): 174-179.
[13] 吴曼, 周阁. 从痰论治多囊卵巢综合征不孕研究进展[J]. 湖南中医杂志, 2023, 39(11): 224-227.
[14] 冉雪梦. 基于窠囊论治肥胖型多囊卵巢综合征[J]. 中医药通报, 2022, 21(4): 29-31.
[15] 陈旭. 从“肾脾两虚, 痰瘀壅络”论多囊卵巢综合征病机[J]. 中国中医基础医学杂志, 2016, 22(2): 267-269.
[16] 姜西利, 李伟莉, 张红. 基于“肥胖不孕”理论从脾论治肥胖型多囊卵巢综合征不孕症[J]. 山西中医药大学学报, 2024, 25(7): 753-758.
[17] 杨明丽, 王东红, 王梦雨, 等. 基于“自气成积”探究气郁在多囊卵巢综合征中的始基作用[J/OL]. 中医学报: 1-5.
https://read.cnki.net/web/Journal/Article/HNZK20241218002.html, 2025-06-02.
[18] 闫菲, 刘雁峰, 史云, 等. 基于“阳化气, 阴成形”理论探讨排卵障碍的中医证治[J]. 中医学报, 2022, 37(2): 263-266.
[19] 张可欣, 康志媛. 基于“阳化气, 阴成形”论治肥胖型多囊卵巢综合征[J/OL]. 中医学报: 1-9.
http://kns.cnki.net/kcms/detail/41.1411.R.20240826.1033.030.html, 2025-06-04.