鹦鹉热衣原体引起重症肺炎1例诊治并文献复习

Diagnosis and Treatment of a Case of Severe Pneumonia Caused by Chlamydia psittaci: A Case Report and Literature Review

摘要: 目的：讨论鹦鹉热病原体引发重症肺炎的临床诊断、治疗及预后。方法：回顾陕西省人民医院2023年收治的一例鹦鹉热衣原体感染患者的临床资料，并进行相关文献复习。结果：患者男性，49岁，初期表现为间断高热，后引起重症肺炎，随后完善痰培养、血培养及mNGS检查确诊鹦鹉热衣原体感染，予以利奈唑胺治疗，半年后随访未再复发。讨论：鹦鹉热衣原体感染引起重症肺炎相关病例少，病情进展快，临床表现缺乏特异性，虽有针对性的治疗药物，但需做到早期诊断及治疗，总体预后不佳。

Abstract: Objective: To discuss the clinical diagnosis, treatment, and prognosis of severe pneumonia caused by the pathogen of psittacosis. Methods: A case of Chlamydia psittaci infection admitted to the People’s Hospital of Shaanxi Province in 2023 was reviewed, and relevant literature was revisited. Results: The patient, a 49-year-old male, initially presented with intermittent high fever, which later progressed to severe pneumonia. Subsequent sputum culture, blood culture, and metagenomic next-generation sequencing (mNGS) confirmed the diagnosis of Chlamydia psittaci infection. The patient was treated with linezolid and followed up six months later with no recurrence. Discussion: Cases of severe pneumonia caused by Chlamydia psittaci infection are rare. The disease progresses rapidly, and clinical manifestations lack specificity. Although there are targeted treatments available, early diagnosis and treatment are crucial. The overall prognosis is generally poor.