回顾性分析象皮膏及压疮散对2、3期压力性损伤的临床疗效及经济效益

A Retrospective Study on the Clinical Efficacy and Economic Benefits of Xiangpi Ointment and Pressure Ulcer Powder in the Management of Stages II and III Pressure Injuries

摘要: 目的：研究分析象皮膏及压疮散治疗2、3期压力性损伤的临床疗效及经济性，为丰富压力性损伤的临床中医外治方法提供参考。方法：回顾性选取2024年05月至2025年03月在成都中医药大学附属眉山医院眉山市中医医院收治住院的“2、3期压力性损伤”患者58例作为研究对象，所有患者均积极治疗原发疾病及压疮基础治疗。外敷象皮膏共27例，外敷“压疮散 + 象皮膏”共17例，外敷重组牛碱性成纤维细胞生长因子凝胶(贝复新)共14例。3组均每日外敷药物1次，干预治疗9天。对比分析3组患者的压力性损伤愈合量表得分、创面愈合率、压疮药物费用、患者满意度等情况。结果：象皮膏、压疮散 + 象皮膏、贝复新各组治疗2、3期压力性损伤疗效均显著，压力性损伤愈合量表得分、创面愈合率各组治疗前后均具有统计学差异(P < 0.001)，但组间对比无统计学差异(P > 0.05)。3组患者的满意度对比无统计学差异(P > 0.05)。压疮药物费用比较，象皮膏花费最少，且组间对比有统计学差异(P < 0.001)。结论：象皮膏、压疮散 + 象皮膏、贝复新治疗压力性损伤的疗效确切且相近，但象皮膏更经济适用，值得进一步研究推广。

Abstract: Objective: To investigate and analyze the clinical efficacy and cost-effectiveness of Xiangpi ointment and Pressure Ulcer Powder in the treatment of stages II and III pressure injuries, providing reference for enriching traditional Chinese external therapies for pressure injuries. Methods: A retrospective study was conducted on 58 inpatients with stages II and III pressure injuries admitted to Traditional Chinese Medicine Hospital of Meishan, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, from May 2024 to March 2025. All patients received active treatment for primary diseases and basic care for pressure injuries. Among them, 27 patients were treated with Xiangpi ointment alone, 17 with Xiangpi ointment combined with Pressure Ulcer Powder, and 14 with recombinant bovine basic fibroblast growth factor gel (Beifuxin). All groups received topical medication once daily for 9 days. The Pressure Ulcer Scale for Healing (PUSH) score, wound healing rate, medication cost, and patient satisfaction were compared among groups. Results: All three treatments—Xiangpi ointment, Xiangpi ointment plus Pressure Ulcer Powder, and Beifuxin—achieved significant therapeutic effects for stages II and III pressure injuries. PUSH scores and wound healing rates improved significantly within each group (P < 0.001), with no significant differences between groups (P > 0.05). Patient satisfaction did not differ significantly among the three groups (P > 0.05). However, the cost of Xiangpi ointment was the lowest, with statistically significant differences between groups (P < 0.001). Conclusion: Xiangpi ointment, Xiangpi ointment combined with Pressure Ulcer Powder, and Beifuxin are all effective treatments for pressure injuries, with comparable efficacy. However, Xiangpi ointment is more cost-effective, making it worthy of further study and wider application.