“岭南湿热质”对脊柱感染患者的临床影响分析
Analysis of the Clinical Impact of “Lingnan Damp-Heat Constitution” on Patients with Spinal Infections
DOI: 10.12677/tcm.2026.151026, PDF,    科研立项经费支持
作者: 桑莉莉*, 王伟群, 吴俊哲:广东省中山市中医院脊柱科,广东 中山
关键词: 湿热质脊柱感染功能障碍岭南Damp-Heat Constitution Spinal Infection Functional Impairment Lingnan
摘要: 目的:岭南湿热质导致患者脊柱感染反复、病程迁延难愈,探讨“岭南湿热质”对脊柱感染患者的临床影响分析。方法:回顾性研究2024年1月至2025年06月在中山市中医院就诊脊柱感染患者45例。根据患者问诊、舌脉及病史情况进行辩证,根据辩证结果分组,分为湿热证型组(共25例)和对照组(共20例)。统计不同证型脊柱感染患者性别、年龄、病程、C反应蛋白(CRP)、红细胞沉降率(ESR)、降钙素原(PCT)、视觉模拟疼痛评分(VAS)以及脊柱功能障碍指数(ODI)等。结果:湿热组年龄50~77岁,平均64.16 ± 8.97岁,病程1~12周,平均6.88 ± 2.95周,对照组年龄43~78岁,平均56.6 ± 11.26岁,病程0~8周,平均3.35 ± 2.16周。两组数据对比,在性别方面差异无统计学意义,在年龄、病程方面数据有统计学差异。两组患者感染指标CRP、ESR、PCT比较无统计学差异,但从平均值可见湿热组患者CRP、ESR、PCT均高于对照组。两组患者感染指标VAS评分、ODI功能评分比较有显著差异,湿热组患者VAS评分、ODI功能评分均高于对照组。结论:临床治疗方面需注意湿热质患者病程较长、感染指标较高、功能较差,为脊柱感染的预防、诊断和治疗提供新的思路和方法。
Abstract: Objective: To investigate the clinical impact of Lingnan damp-heat constitution on patients with recurrent spinal infections and prolonged disease courses that are difficult to cure. Method: A retrospective study was conducted on 45 patients with spinal infections who visited Zhongshan Traditional Chinese Medicine Hospital from January 2024 to June 2025. According to the patient’s diagnosis, tongue pulse, and medical history, they were divided into two groups based on the dialectical, the damp heat syndrome group (25 cases in total) and the control group (20 cases in total). Statistics on gender, age, disease duration, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalcitonin (PCT), visual analogue scale score (VAS) and Oswestry disability index (ODI) of patients with different types of spinal infections were collected. Result: The age range of the damp heat group was 50~77 years old, with an average of 64.16 ± 8.97 years old, and the disease course was 1~12 weeks, with an average of 6.88 ± 2.95 weeks. The age range of the control group was 43~78 years old, with an average of 56.6 ± 11.26 years old, and the disease course was 0~8 weeks, with an average of 3.35 ± 2.16 weeks. There was no statistically significant difference in gender between the two sets of data, but there were statistical differences in age and disease duration. There was no statistically significant difference in the infection indicators CRP, ESR, and PCT between the two groups of patients, but the average values showed that the CRP, ESR, and PCT in the damp heat group were higher than those in the control group. There was a significant difference in the VAS score and ODI functional score of infection indicators between the two groups of patients. The VAS score and ODI functional score of patients in the damp heat group were higher than those in the control group. Conclusion: In clinical treatment, attention should be paid to patients with damp heat constitution who have a longer disease course, higher infection indicators, and poorer function, providing new ideas and methods for the prevention, diagnosis, and treatment of spinal infections.
文章引用:桑莉莉, 王伟群, 吴俊哲. “岭南湿热质”对脊柱感染患者的临床影响分析[J]. 中医学, 2026, 15(1): 181-187. https://doi.org/10.12677/tcm.2026.151026

参考文献

[1] Luzzati, R., Giacomazzi, D., Danzi, M.C., Tacconi, L., Concia, E. and Vento, S. (2009) Diagnosis, Management and Outcome of Clinically-Suspected Spinal Infection. Journal of Infection, 58, 259-265. [Google Scholar] [CrossRef] [PubMed]
[2] 周润津, 庞博, 刘兴华, 等. 岭南地区湿热证研究进展[J]. 广州中医药大学学报, 2021, 38(5): 1071-1076.
[3] 胡玲, 贾景, 贺颖, 等. 岭南名医劳绍贤教授“脾胃湿热证”创新学术思想撷萃[J]. 中国中西医结合消化杂志, 2024, 32(10): 859-862.
[4] Chiarotto, A., Maxwell, L.J., Ostelo, R.W., Boers, M., Tugwell, P. and Terwee, C.B. (2019) Measurement Properties of Visual Analogue Scale, Numeric Rating Scale, and Pain Severity Subscale of the Brief Pain Inventory in Patients with Low Back Pain: A Systematic Review. The Journal of Pain, 20, 245-263. [Google Scholar] [CrossRef] [PubMed]
[5] Fairbank, J.C.T. and Pynsent, P.B. (2000) The Oswestry Disability Index. Spine, 25, 2940-2953. [Google Scholar] [CrossRef] [PubMed]
[6] Babic, M. and Simpfendorfer, C.S. (2017) Infections of the Spine. Infectious Disease Clinics of North America, 31, 279-297. [Google Scholar] [CrossRef] [PubMed]
[7] Kim, C.J., Song, K.H., Jeon, J.H., Park, W.B., Park, S.W., Kim, H., et al. (2010) A Comparative Study of Pyogenic and Tuberculous Spondylodiscitis. Spine, 35, E1096-E1100. [Google Scholar] [CrossRef] [PubMed]
[8] Hidalgo-Ovejero, A.M., Otermin, I. and Garcia-Mata, S. (1998) Pyogenic Vertebral Osteomyelitis. The Journal of Bone and Joint Surgery, 80, 764.
[9] Zhou, H.X., Ning, G.Z., Feng, S.Q., et al. (2013) Cryptococcosis of Lumbar Vertebra in a Patient with Rheumatoid Arthritis and Scleroderma: Case Report and Literature Review. BMC Infectious Diseases, 13, Article No. 128. [Google Scholar] [CrossRef] [PubMed]
[10] 刘钰熙, 冯大雄, 张洪, 等. 脊柱感染性疾病诊断及鉴别诊断研究进展[J]. 国际骨科学杂志, 2024, 45(5): 315-318.
[11] 黄艳, 沈海良, 寿月华, 等. 脊柱损伤老年患者医院感染因素分析及预测[J]. 实用预防医学, 2024, 31(10): 1230-1233.
[12] 巢元方. 诸病源候论[M]. 黄作阵, 点校. 沈阳: 辽宁科学技术出版社, 1997: 149, 155, 187.
[13] 彭胜权. 岭南温病学说形成和研究现状[J]. 广州中医药大学学报. 1993, 10(4): 230-231.
[14] 祁松, 钱洋, 潘晋方. 体检人群幽门螺杆菌感染与中医体质、糖脂代谢相关性研究[J]. 安徽中医药大学学报, 2023, 42(2): 18-21.
[15] 方俐晖, 张佳琪, 唐旭东. 湿热证诊疗的现代研究进展[J]. 中华中医药杂志, 2024, 39(9): 4793-4798.
[16] 徐慧聪, 彭天托, 邓屹琪, 等. 岭南地区流感患者中医辨证分型聚类分析研究[J]. 广州中医药大学学报, 2021, 38(8): 1547-1552.