基于腑以通为用理论讨论脓毒症胃肠功能障碍的中医药治疗进展
Recent Advances in TCM Therapy for Sepsis-Associated Gastrointestinal Dysfunction Guided by the “Fu Yi Tong Wei Yong” Principle
DOI: 10.12677/tcm.2026.152078, PDF,   
作者: 廖晓滢, 周 宜*:成都中医药大学基础医学院,四川 成都
关键词: 脓毒症胃肠功能障碍腑以通为用承气汤Sepsis Gastrointestinal Dysfunction Fu Yi Tong Wei Yong Chengqi Tang
摘要: 胃肠功能障碍(Gastrointestinal Dysfunction, GID)是脓毒症患者常见的并发症,也是影响患者预后的关键因素。《黄帝内经》中提出了“腑以通为用”理论,强调六腑以传导通畅为基本功能,病机核心在于不通,该理论指导下的通腑治法与脓毒症GID的热结腑实、腑气不通病机契合。本文旨在系统综述腑以通为用理论指导下,中医药治疗脓毒症胃肠功能障碍的现代临床研究进展,归纳常用治法与方药、穴位规律,对未来临床研究方向提出展望。
Abstract: Gastrointestinal Dysfunction (GID) is a common complication in patients with sepsis and a crucial determinant of prognosis. The theory of “Fu Yi Tong Wei Yong”, originating from the Huangdi Neijing, posits that the fundamental function of the Fu-organs is to maintain unimpeded flow, with obstruction being the core of their pathogenesis. The “Tong-Fu” therapeutic method, guided by this principle, aligns well with the pathogenesis of sepsis-induced GID, which is characterized by heat accumulation with stool impaction and obstruction of Fu-organ Qi. This paper aims to systematically review the recent clinical research progress of Traditional Chinese Medicine (TCM) in managing sepsis-induced GID, summarize the commonly used therapeutic strategies, herbal formulas, and acupoint application patterns, and provide an outlook on future research directions.
文章引用:廖晓滢, 周宜. 基于腑以通为用理论讨论脓毒症胃肠功能障碍的中医药治疗进展[J]. 中医学, 2026, 15(2): 87-90. https://doi.org/10.12677/tcm.2026.152078

参考文献

[1] Singer, M., Deutschman, C.S., Seymour, C.W., Shankar-Hari, M., Annane, D., Bauer, M., et al. (2016) The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA, 315, 801-810. [Google Scholar] [CrossRef] [PubMed]
[2] Guo, N., She, H., Tan, L., Zhou, Y., Tang, C., Peng, X., et al. (2023) Nano Parthenolide Improves Intestinal Barrier Function of Sepsis by Inhibiting Apoptosis and ROS via 5-HTR2A. International Journal of Nanomedicine, 18, 693-709. [Google Scholar] [CrossRef] [PubMed]
[3] Malbrain, M.L.N.G., Chiumello, D., Pelosi, P., Bihari, D., Innes, R., Ranieri, V.M., et al. (2005) Incidence and Prognosis of Intraabdominal Hypertension in a Mixed Population of Critically Ill Patients: A Multiple-Center Epidemiological Study. Critical Care Medicine, 33, 315-322. [Google Scholar] [CrossRef] [PubMed]
[4] 田代华. 黄帝内经素问[M]. 北京: 人民卫生出版社, 2017: 165.
[5] 张仲景, 何任, 何若苹. 金匮要略[M]. 北京: 人民卫生出版社, 2017: 110.
[6] 李叔潼, 王欣宇, 严章荣, 等. 承气汤类方治疗术后胃肠功能障碍临床疗效和安全性Meta分析[J]. 亚太传统医药, 2024, 20(5): 153-161.
[7] 孟祥睿, 李洁, 杨志旭, 等. 中西医治疗脓毒症胃肠功能障碍的疗效[J]. 实用医学杂志, 2019, 35(9): 1504-1507.
[8] 姚晨思, 田传玺, 张湘苑, 等. 仝小林院士应用宣白承气汤加减治疗新冠重症经验[J]. 吉林中医药, 2023, 43(10): 1158-1160.
[9] 张丽英. 生大黄粉煎剂保留灌肠对ICU患者胃肠功能影响的疗效观察[J]. 中医临床研究, 2018, 10(12): 10-11.
[10] 李艳君, 郭瑞敏, 孙燕妮. 大黄素改善脓毒症肠机械屏障损伤的研究进展[J]. 中国中医急症, 2019, 28(3): 542-545.
[11] 樊紫阳, 廉金玉, 郑雅蔓, 等. 针刺辅助治疗脓毒症胃肠功能障碍疗效及安全性的Meta分析[J]. 中国循证医学杂志, 2025, 25(5): 532-537.
[12] 刘宇, 贺海东, 王兰, 等. 超声评估电针改善危重症患者胃动力功能的临床研究[J]. 临床急诊杂志, 2017, 18(12): 902-906.
[13] 胡柏生, 谭美春, 施巍, 等. 大黄芒硝外敷神阙穴治疗重症肺炎机械通气患者急性胃肠损伤的临床研究[J]. 现代中西医结合杂志, 2024, 33(18): 2583-2587.