双源64排CT低剂量扫描在冠脉支架再狭窄中的临床应用

Clinical Application of Low-Dose Dual-Source 64-Slice CT in Coronary Stent Restenosis

摘要: 目的：探讨双源64排CT低剂量扫描在冠脉支架再狭窄中的临床应用。方法：回顾30例患者，支架置入的冠脉重度狭窄患者的临床资料。所有患者均行双源64排CT低剂量检查、冠状动脉造影检查，将二者比较，评估双源64排CT低剂量扫描对支架再狭窄诊断的阴性预测值、阳性预测值、敏感度及特异度。结果：30例研究对象共放支架72支，共36支支架诊断为再狭窄，包括轻度狭窄15支、中度狭窄15支、重度狭窄6支，对比冠脉造影，重度狭窄：准确率、阴性预测值、阳性预测值、敏感度及特异度分别为：97%、92%、94%、91%、95%。中度狭窄：准确率、阴性预测值、阳性预测值、敏感度及特异度分别为：95%、89%、86%、90%、91%。轻度狭窄：准确率、阴性预测值、阳性预测值、敏感度及特异度分别为：94%、85%、84%、87%、82%。结论：双源64排CT低剂量扫描能准确诊断冠状动脉支架再狭窄。

Abstract: Objective: To investigate the clinical application of low-dose dual-source 64-slice CT in coronary stent restenosis. Methods: The clinical data of 30 patients with severe coronary stenosis after stent implantation were reviewed. All patients underwent low-dose dual-source 64-slice CT and coronary angiography. The negative predictive value, positive predictive value, sensitivity and specificity of low-dose dual-source 64-slice CT in the diagnosis of stent restenosis were evaluated. Results: Thirty-six stents were diagnosed as restenosis, including 15 mild stenosis, 15 moderate stenosis and 6 severe stenosis. Compared with coronary angiography, the accuracy, negative predictive value, positive predictive value, sensitivity and specificity of severe stenosis were 97%, 92%, 94%, 91% and 95%, respectively. Moderate stenosis: accuracy, negative predictive value, positive predictive value, sensitivity and specificity were 95%, 89%, 86%, 90%, 91%, respectively. Mild stenosis: accuracy, negative predictive value, positive predictive value, sensitivity and specificity were 94%, 85%, 84%, 87%, 82%, respectively. Conclusion: Low-dose dual-source 64-slice CT can accurately diagnose coronary stent restenosis.