霉菌毒素生物解毒剂对肉鸡器官指数和血清指标的影响

Effect of Mycotoxin Biological Antidote on Organ Index and Serum Index of Broilers

摘要: 目的：本文旨在研究含有黄曲霉毒素B₁ (AFB₁)和玉米赤霉烯酮(ZEA)饲料中添加生物解毒剂对肉鸡器官指数和血清指标的影响。方法：选取22日龄健康罗斯308肉仔鸡150只，随机分为3个组，每组5个重复，每个重复10只鸡。分组为：1) 基础日粮；2) 基础日粮 + AFB₁ 50 µg/kg + ZEA 500 µg/kg；3) 基础日粮 + AFB₁ 50 µg/kg + ZEA 500 µg/kg + 生物解毒剂。结果：结果表明：添加生物解毒剂显著提高肉鸡肝脏和脾脏指数、小肠和大肠相对长度(P < 0.05)，增加了血清中谷丙转氨酶、总蛋白、白蛋白和甘油三酯含量(P < 0.05)，降低了血清内毒素(P > 0.05)和碱性磷酸酶(P < 0.05)。结论：这表明在含AFB1 50 µg/kg + ZEA 500 µg/kg饲料中添加生物解毒剂能够缓解毒素对机体的损伤。

Abstract: Objective: This study was conducted to investigate the effects of mycotoxin biological antidote (MBDP) on organ index and serum index of broilers fed with diets containing aflatoxin B₁ and zearalenone. Method: A total of 150 of 22-day-old Rose 308 broilers were randomly distributed into 3 groups. The broilers from group 1 to group 3 were fed with basal diet, basal diet containing AFB₁ 50 µg/kg + ZEA 500 µg/kg and basal diet containing AFB₁ 50 µg/kg + ZEA 500 µg/kg + MBDP, respectively. Result: The results showed that adding MBDP significantly increased liver and spleen index (P < 0.05), the relative length of small intestine and large intestine and the content of alanine-transferase (ALT), total protein, albumin and triglyceride in serum (P < 0.05), decreased endotoxin (P > 0.05) and alkaline phosphatase (P < 0.05) inserum. Conclusion: It could be concluded that adding MBDP in basal diet containing AFB1 50 µg/kg + ZEA 500 µg/kg could alleviate mycotoxin hazard.