结核病易感因素及相关机制研究
Study on Susceptible Factors and Related Mechanisms of Tuberculosis
DOI: 10.12677/ACM.2021.113134, PDF,    科研立项经费支持
作者: 李百远:延安大学附属医院,陕西 延安;李元军*:延安大学附属医院,陕西 延安;延安市第二人民医院,陕西 延安
关键词: 结核易感因素机制Tuberculosis Susceptible Factors Mechanism
摘要: 结核病作为一种慢性传染病,其发病是由遗传易感性、环境、社会经济状况等综合作用的结果。目前,多项研究探讨结核病发病危险因素,包括老年、糖尿病、吸烟、饮酒、营养不良、手机依赖、睡眠障碍等,但关于这些危险因素如何增加结核分枝杆菌易感性机制,与机体免疫学具体关联是什么,相关报道较少。因此,本文主要从特定人群、不良生活方式两方面入手,就以上易感因素与结核病之间的关联作一综述,总结不同人群对结核分枝杆菌易感性相关机制,为结核病个体精准化防治提供理论依据。
Abstract: As a chronic infectious disease, the incidence of tuberculosis is the result of genetic susceptibility, environment, socio-economic status and other comprehensive effects. At present, a number of studies have explored the risk factors of tuberculosis, including old age, diabetes, smoking, drinking, malnutrition, cell phone dependence, sleep disorders and so on, but there are few reports on how these risk factors increase the susceptibility mechanism of Mycobacterium tuberculosis and what is specifically related to immunology. Therefore, this paper mainly reviews the relationship between the above susceptible factors and tuberculosis from the two aspects of specific population and bad life style, and summarizes the mechanism of susceptibility to Mycobacterium tuberculosis in different populations, to provide theoretical basis for individual accurate prevention and treatment of tuberculosis.
文章引用:李百远, 李元军. 结核病易感因素及相关机制研究[J]. 临床医学进展, 2021, 11(3): 930-938. https://doi.org/10.12677/ACM.2021.113134

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