多囊卵巢综合征与代谢综合征相关性研究进展

Research Progress on the Correlation between Polycystic Ovary Syndrome and Metabolic Syndrome

摘要: 多囊卵巢综合征(polycystic ovarian syndrome, PCOS)，是一种多见于青春期起病的妇科内分泌疾病。而代谢综合征(metabolic syndrome, MS)是一组以人体蛋白质、脂肪、碳水化合物等物质发生代谢紊乱的复杂代谢症候群。MS和PCOS都是育龄期女性的常见疾病，都可伴有肥胖和胰岛素抵抗(RI)，所以将MS和PCOS结合起来研究时，二者重叠的部分最有研究价值。随着PCOS研究的深入，其发病机制有了新的进展，且与MS密切相关。更具体地说，与同年龄的普通人群相比，PCOS患者MS的发病率更高。所以研究PCOS与MS的相关性，对于后期我们在诊断、治疗和预防PCOS患者发生MS方面有重要意义。本文就PCOS与MS的相关性作一综述。

Abstract: Polycystic ovarian syndrome (PCOS) is one of the common gynecological endocrine diseases. The onset of disease is more common in adolescence, characterized by high androgen clinical or biochemical manifestations, persistent anovulation, ovarian polycystic changes, often accompanied by insulin resistance and obesity. And metabolic syndrome (MS) refers to the pathological state of metabolic disorder of protein, fat, carbohydrate and other substances in human body, which is a group of complex metabolic syndrome. At the heart of MS is obesity and insulin resistance. MS and PCOS are common diseases in women of childbearing age, and when MS and PCOS are combined to study, the most valuable part is the overlap between them. With the deepening of PCOS research, its pathogenesis has made new progress and is closely related to MS. More specifically, the incidence of MS in PCOS patients is higher than in the general population of the same age. Therefore, the study of the correlation between PCOS and MS is of great significance to the later diagnosis, treatment and prevention for MS patients.