二维声子晶体传感器应用于葡萄糖浓度的检测研究

Application of Two-Dimensional Phononic Crystal Sensor in Glucose Concentration Measurement

摘要: 本文提出了一种二维缺陷声子晶体传感器设计，实现了对葡萄糖浓度的检测。传感器设计是汞作为基体，周期性排列的充水圆形散射体的正方晶格结构，在共振腔中引入不同浓度的葡萄糖溶液使其在周期性结构中起到缺陷的作用。基于有限元法(FEM)进行了数值模拟，传感器输入值是葡萄糖的浓度，输出值是共振峰值频率。结果表明，共振峰值频率随波导中葡萄糖浓度的变化而显著不同。通过对峰值频率的研究，该传感器对葡萄糖浓度具有较高的传感性能。葡萄糖浓度为54.6%时灵敏度、Q值分别为66,891 Hz和2235。这些结果表明，二维缺陷声子晶体传感器具有高灵敏度、高Q值、制作简单、成本低等优点，是检测葡萄糖的理想选择。该研究结果为二维声子晶体传感器在不使用葡萄糖氧化酶产生催化作用的情况下，对于血液中葡萄糖浓度的检测提供了理论依据。

Abstract: In this paper, a two-dimensional defect phononic crystal sensor design is proposed to realize the detection of glucose concentration. The sensor design consists of a square arrangement of mercury as a matrix and a periodic array of circular scatterers filled with water, and the introduction of different concentrations of glucose solutions into the resonant cavity makes it act as a defect in the periodic structure. Numerical simulation was carried out based on the finite element method (FEM), the input value of the sensor was the glucose concentration, and the output value was the resonance peak frequency. The results show that the resonance peak frequency varies significantly with the glucose concentration in the waveguide. Through the study of peak frequency, the sensor has high sensing performance for glucose concentration. When the glucose concentration was 54.6%, the sensitivity and Q values were 66,891 Hz and 2235, respectively. These results indicate that the two-dimensional defect phononic crystal sensor has the advantages of high sensitivity, good performance, simple fabrication, and low cost, and is an ideal choice for glucose detection. The results of this study provide a theoretical basis for the detection of glucose concentration in blood by two-dimensional phononic crystal sensors without the use of glucose oxidase to generate catalysis.