纤维蛋白原/前白蛋白在慢性阻塞性肺疾病急性加重期诊疗中的研究进展
Research Progress of Fibrinogen/Prealbumin in the Diagnosis and Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
摘要: 慢性阻塞性肺疾病(chronic obstructive pulmonary disease, COPD)简称慢阻肺，是一种以渐进性呼吸困难及肺功能下降为特征的慢性气道疾病。大多数患者每年发生至少一次急性加重，频繁发生的慢性阻塞性肺疾病急性加重(acute exacerbation of chronic obstructive pulmonary disease, AECOPD)是导致慢阻肺患者生活质量下降、住院次数增多及死亡风险升高的主要原因。肺功能测试易于实施，验证了COPD的疾病进展和严重程度，但较多患者就诊时，因处于不能耐受的缺氧状态或伴发其它疾病无法进行该项检查，因此，入院时可检测的简便易行、可重复测量的血清学指标对于评估COPD患者的诊断及预后非常重要，本文对炎症指标及纤维蛋白原/前白蛋白在AECOPD中的诊断及评估预后作一综述。
Abstract: Chronic obstructive pulmonary disease (COPD) is a chronic airway disease characterized by pro-gressive dyspnea and decreased lung function. Most patients suffer from acute exacerbations at least once a year and frequent acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the main cause of decreased quality of life, increased hospitalization times and in-creased risk of death in COPD patients. The pulmonary function test is easy to implement and veri-fies the disease progression and severity of COPD. However, many patients cannot perform this test because they are in an intolerable state of hypoxia or accompanied by other diseases. Therefore, the simple, easy and repeatable serological indexes that can be detected at admission are very im-portant for evaluating the diagnosis and prognosis of COPD patients. This article reviews the diag-nosis and prognosis assessment of inflammatory indexes and fibrinogen/prealbumin in AECOPD.
文章引用：谢静静, 常小红, 汪檬. 纤维蛋白原/前白蛋白在慢性阻塞性肺疾病急性加重期诊疗中的研究进展[J]. 临床医学进展, 2022, 12(12): 11031-11036. https://doi.org/10.12677/ACM.2022.12121589

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