榆林地区精神分裂患者发病与出生季节、发病季节及气候的相关性
Correlation among the Onset of Schizophrenia in Yulin Region and Birth Season, Disease Onset Season, and Climate
DOI: 10.12677/ACM.2024.141094, PDF,    科研立项经费支持
作者: 毛 艳*, 冯玉宏#, 黄文琴:榆林市第五医院心身医学科,陕西 榆林
关键词: 精神分裂症出生季节气候Schizophrenia Birth Season Climate
摘要: 目的:探讨榆林地区精神分裂症患者发病与出生季节、发病季节及发病气候要素的相关性。方法:对榆林地区2019年10月至2022年6月入院的精神分裂症患者病历资料进行整理分析,对其出生季节、发病季节进行分析,将其月入院量与同期月平均温度、平均大气压与平均湿度进行Logistic回归分析。结果:精神分裂症患者秋季、冬季、春季出生的概率明显高于夏季(P < 0.05),精神分裂症患者秋季发病的概率明显高于其他季节(P < 0.05),月平均气压上升是患者月入院量促进因素(P < 0.05),月平均气温升高是减少患者月入院量的因素(P < 0.05)。结论:榆林地区精神分裂症患者的出生及发病均存在季节性,且与部分气候因素有相关性。应根据时间和环境变化,采取适当措施,加强照护,以减少发病。
Abstract: Objective: To explore the correlation between the onset of schizophrenia in Yulin area and the fac-tors of birth season, onset season, and onset climate. Method: The medical records of schizophrenia patients admitted to the Yulin area from October 2019 to June 2022 were sorted and analyzed. The birth season and onset season were analyzed, and the monthly admission volume was compared with the monthly average temperature, average atmospheric pressure, and average humidity dur-ing the same period through Logistic regression analysis. Result: The probability of birth in autumn, winter, and spring in patients with schizophrenia was significantly higher than in summer (P < 0.05), and the probability of onset in autumn was significantly higher than in other seasons (P < 0.05). The increase in monthly average air pressure was a promoting factor for the monthly admis-sion of patients (P < 0.05), while the increase in monthly average temperature was a reducing factor for the monthly admission of patients (P < 0.05). Conclusion: The birth and onset of schizophrenia in Yulin area are seasonal and correlated with some climate factors. Appropriate measures should be taken based on time and environmental changes to strengthen care and reduce the incidence of diseases.
文章引用:毛艳, 冯玉宏, 黄文琴. 榆林地区精神分裂患者发病与出生季节、发病季节及气候的相关性[J]. 临床医学进展, 2024, 14(1): 676-680. https://doi.org/10.12677/ACM.2024.141094

参考文献

[1] 王冉然. 基于《黄帝内经》“天人合一”思想的精神分裂症发病风险因素研究[D]: [博士学位论文]. 北京: 北京中医药大学, 2021.[CrossRef
[2] 黄悦琦, 张丽娜, 吴哲, 等. 杭州某三甲精神专科医院住院精神疾病患者季节分布特征[J]. 浙江医学, 2019, 41(18): 2008-2010.
[3] Wahbeh, M.H. and Avramopoulos, D. (2021) Gene-Environment Interactions in Schizophrenia: A Literature Review. Genes (Basel), 12, 1850. [Google Scholar] [CrossRef] [PubMed]
[4] 王勋, 马宁, 吴霞民, 等. 2018年全国严重精神障碍患者管理治疗现状分析[J]. 中华精神科杂志, 2020, 53(5): 438-445.
[5] Huang, Y., Wang, Y., Wang, H., et al. (2019) Prevalence of Mental Disorders in China: A Cross-Sectional Epidemiological Study. Lancet Psychiatry, 6, 211-224. [Google Scholar] [CrossRef
[6] Buckles, K.S. and Hungerman, D.M. (2013) Season of Birth and Later Outcomes: Old Questions, New Answers. The Review of Economics and Statistics, 95, 711-724. [Google Scholar] [CrossRef
[7] Chiang, M., Natarajan, R. and Fan, X. (2016) Vitamin D in Schizo-phrenia: A Clinical Review. BMJ Mental Health, 19, 6-9. [Google Scholar] [CrossRef] [PubMed]
[8] Zhao, D., Zhang, X., Xu, Z., et al. (2017) Impact of Short-Term Temperature Variability on Emergency Hospital Admissions for Schizophrenia Stratified by Season of Birth. International Journal of Biometeorology, 61, 589-599. [Google Scholar] [CrossRef] [PubMed]
[9] Davies, G., Welham, J., Chant, D., Torrey, E.F. and McGrath, J. (2003) A Systematic Review and Meta-Analysis of Northern Hemisphere Season of Birth Studies in Schizophrenia. Schizophrenia Bulletin, 29, 587-593. [Google Scholar] [CrossRef] [PubMed]
[10] 任衍镇, 杜宝国, 劳钊明. 急性而短暂的精神病性障碍发病与季节及气象要素的相关性[J]. 中国当代医药, 2018, 25(13): 57-60.
[11] Flory, R., Ametepe, J. and Bowers, B. (2010) A Randomized, Placebo-Controlled Trial of Bright Light and High-Density Negative Air Ions for Treatment of Seasonal Affective Disorder. Psychiatry Research, 177, 101-108. [Google Scholar] [CrossRef] [PubMed]
[12] Bowers, B., Flory, R., Ametepe, J., Staley, L., Patrick, A. and Carrington, H. (2018) Controlled Trial Evaluation of Exposure Duration to Negative Air Ions for the Treatment of Seasonal Affective Disorder. Psychiatry Research, 259, 7-14. [Google Scholar] [CrossRef] [PubMed]
[13] 王薇. 空气负离子浓度分布特征及其与环境因子的关系[J]. 生态环境学报, 2014, 23(6): 979-984. [Google Scholar] [CrossRef
[14] 李丹. 榆林地区呼吸道过敏性疾病致敏谱特征及哮喘患者免疫功能差异比较研究[D]: [硕士学位论文]. 延安: 延安大学, 2022.[CrossRef