间充质干细胞关节腔注射治疗膝骨关节炎的临床研究进展
Research Progress of Mesenchymal Stem Cell Intra-Articular Injection in the Treatment of Keen Osteoarthritis
DOI: 10.12677/ACM.2024.143705, PDF,   
作者: 马军涛：黑龙江中医药大学研究生院，黑龙江 哈尔滨；田 泽：广西中医药大学瑞康医院神经内科二区，广西 南宁；孟宪宇*：黑龙江中医药大学附属第一医院骨伤二科，黑龙江 哈尔滨
关键词: 间充质干细胞药；注射治疗；膝骨关节炎；动物实验；临床试验；Mesenchymal Stem Cells； Injection Therapy； Knee Osteoarthritis； Animal Experiment； Clinical Trials
摘要: 随着人口老龄化不断加剧，膝骨关节炎(keen osteoarthritis, KOA)发病率逐步升高，目前中国大陆地区中老年患者KOA的发病率为8.1%，自体间充质干细胞(mesenchymal stem Cell, MSC)治疗KOA作为一种新兴的治疗手段，目前已有大量动物实验和临床试验，本综述通过检索“PubMed数据库”，“CNKI数据库”中近5年的动物实验、临床试验，通过归纳总结，对MSc治疗KOA的最新进展进行评述。
Abstract: With the aging of the population, the incidence of knee osteoarthritis is gradually increasing. At present, the incidence of KOA in middle-aged and elderly patients in mainland China is 8.1%. Au-tologous mesenchymal stem cells are used to treat KOA as a new treatment method. At present, there are a large number of animal experiments and clinical trials. With the aging of the population, the incidence of knee osteoarthritis (KOA) is gradually increasing. At present, the incidence of KOA in middle-aged and elderly patients in mainland China is 8.1%. Autologous mesenchymal stem cells (MSC) are used to treat KOA as a new treatment method. There are a large number of animal ex-periments and clinical trials. This review summarizes the animal experiments and clinical trials in the past 5 years by searching the “PubMed database” and “CNKI database”. By summarizing, the latest progress of MSc in the treatment of KOA is reviewed.
文章引用：马军涛, 田泽, 孟宪宇. 间充质干细胞关节腔注射治疗膝骨关节炎的临床研究进展[J]. 临床医学进展, 2024, 14(3): 332-337. https://doi.org/10.12677/ACM.2024.143705

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