基于“肝与大肠相通”理论从肝论治肠易激综合征
Based on the Theory of “Liver and Large Intestine Communication”, Treating Irritable Bowel Syndrome from the Perspective of Liver Theory
DOI: 10.12677/acm.2024.1492470, PDF,   
作者: 单心蕾:黑龙江中医药大学研究生院,黑龙江 哈尔滨;刘朝霞*:黑龙江中医药大学附属第一医院肝脾胃科,黑龙江 哈尔滨
关键词: 肝与大肠相通肠易激综合征从肝论治Liver and Large Intestine Connected Irritable Bowel Syndrome Treating from the Perspective of Liver
摘要: 肠易激综合征(irritable bowel syndrome, IBS)是一种间断性或持续性发作,以腹痛、腹胀,伴排便异常或排便习惯改变为表现的肠道功能紊乱性疾病。“肝与大肠相通”深刻解析了肝与大肠的生理病理关系。本文从西医中的“肠肝轴、脑肠轴”理论阐述“肝与大肠相通”理论与IBS的相关性,以现代医学等现代科学知识及手段来继承和发展中医理论,为IBS的诊断、治疗打开了全新视野。
Abstract: Irritable bowel syndrome (IBS) is an intermittent or persistent intestinal dysfunction characterized by abdominal pain, bloating, and abnormal bowel movements or changes in bowel habits. The theory of “the liver and the large intestine communicate” deeply analyzes the physiological and pathological relationship between the liver and the large intestine. This article elaborates on the correlation between the theory of “the connection between the liver and the large intestine” and IBS from the perspectives of the gut liver axis and the brain gut axis in Western medicine. It inherits and develops traditional Chinese medicine theory through modern medical knowledge and methods, opening up a new perspective for the diagnosis and treatment of IBS.
文章引用:单心蕾, 刘朝霞. 基于“肝与大肠相通”理论从肝论治肠易激综合征[J]. 临床医学进展, 2024, 14(9): 368-373. https://doi.org/10.12677/acm.2024.1492470

参考文献

[1] 张声生, 魏玮, 杨俭勤. 肠易激综合征中医诊疗专家共识意见(2017) [J]. 中医杂志, 2017, 58(18): 1614-1620.
[2] Rinninella, E., Cintoni, M., Mele, M.C. and Gasbarrini, A. (2019) Irritable Bowel Syndrome (IBS) and Non-Celiac Gluten Sensitivity (NCGS): Where Is the Culprit Hiding? Nutritional Tips for Gastroenterologists. Nutrients, 11, Article 2499. [Google Scholar] [CrossRef] [PubMed]
[3] 中华医学会消化病学分会胃肠功能性疾病协作组, 中华医学会消化病学分会胃肠动力学组. 2020年中国肠易激综合征专家共识意见[J]. 中华消化杂志, 2020, 40(12): 803-818.
[4] 何力, 杨力, 凌志维, 等. 基于脑肠交互机制探讨肠道微生物调节IBS-D内脏高敏的研究进展[J]. 中国实验方剂学杂志, 2019, 25(11): 224-229.
[5] Gwee, K.A., Gonlachanvit, S., Ghoshal, U.C., Chua, A.S.B., Miwa, H., Wu, J., et al. (2019) Second Asian Consensus on Irritable Bowel Syndrome. Journal of Neurogastroenterology and Motility, 25, 343-362. [Google Scholar] [CrossRef] [PubMed]
[6] 李鲜, 张璐鹏, 李英宵, 等. 腹泻型肠易激综合征的中西医研究现状[J]. 中国中西医结合消化杂志, 2021, 29(4): 298-302.
[7] 巩阳. 王长洪教授从肝脾肾论治肠易激综合征的临床经验[J]. 中国中西医结合消化杂志, 2008, 17(3): 195-196.
[8] 项柏康. 重视肠易激综合征发病机理的研究及中医药治疗[J]. 浙江中医学院学报, 2000, 24(3): 15-16.
[9] 张北华, 高蕊, 李振华, 等. 中医药治疗肠易激综合征的专家经验挖掘分析[J]. 中国中西医结合杂志, 2013, 33(6):757-760.
[10] 梁煜, 赵远红. “肝与大肠相通”的理论内涵初析[J]. 中西医结合肝病杂志, 2023, 33(3): 261-265.
[11] 李梴. 医学入门[M]. 北京: 中国医药科技出版社, 2011: 82.
[12] 唐容川. 唐容川医学全书[M]. 太原: 山西科学技术出版社, 2016: 56.
[13] 毛靖, 陆兔林. 论“肝与大肠相通” [J]. 陕西中医, 2019, 40(7): 927-930.
[14] 尉万春, 李成卫, 王庆国. 唐容川“中西汇通”肝脏理论特点及对后世的影响[J]. 世界中医药, 2015, 10(11): 1658-1611.
[15] 陈英杰. “肝与大肠相通”探析[J]. 中医研究, 2007(11): 3-8.
[16] 印会河. 中医基础理论[M]. 上海: 上海科学技术出版社, 1984: 44.
[17] Li, J., Yuan, M., Liu, Y., Zhao, Y., Wang, J. and Guo, W. (2017) Incidence of Constipation in Stroke Patients. Medicine, 96, e7225. [Google Scholar] [CrossRef] [PubMed]
[18] Mandato, C., Delli Bovi, A.P. and Vajro, P. (2021) The Gut-Liver Axis as a Target of Liver Disease Management. Hepatobiliary Surgery and Nutrition, 10, 100-102. [Google Scholar] [CrossRef] [PubMed]
[19] 周晓凤, 王晓妍, 曹志群. 基于脑-肠轴探析肠易激综合征发病机制[J]. 山东中医药大学学报, 2021, 45(1): 68-71.
[20] Norlin, A., Faresjö, Å., Falk, M., Jones, M.P. and Walter, S. (2019) Primary Healthcare Utilisation and Self-Rated Health among Patients with Irritable Bowel Syndrome: What Are the Impacts of Comorbidities, Gastrointestinal Symptom Burden, Sense of Coherence and Stress? Journal of Psychosomatic Research, 119, 1-7. [Google Scholar] [CrossRef] [PubMed]
[21] 卓冰帆, 张彦卿, 宁晓燕. 痛泻要方合四君子汤加减对腹泻型肠易激综合征患者脑肠肽的影响[J]. 南京中医药大学学报, 2019, 35(1): 25-28.
[22] 张赛. 肠易激综合征中西医发病机制研究概况[J]. 中医临床研究, 2014, 6(3): 48-51.
[23] 吴文军, 刘业方, 郭尹玲. 张之文教授从肝与大肠相通论治炎症性肠病经验[J]. 四川中医, 2017, 35(6): 24-26.
[24] 张星星, 吴坚, 裴丽霞, 等. 健脾疏肝法对腹泻型肠易激综合征患者疗效观察及对肠道菌群的影响[J]. 中国实验方剂学杂志, 2019, 25(13): 79-86.