汉黄芩素的药理作用综述
Review of Pharmacological Effects of Wogonin
DOI: 10.12677/tcm.2024.1311448, PDF,    科研立项经费支持
作者: 李忠鑫：济宁医学院临床医学院，山东 济宁；山东省心血管疾病诊疗重点实验室，山东 济宁；陈雪英, 甘立军*：山东省心血管疾病诊疗重点实验室，山东 济宁；济宁医学院附属医院冠心病四区，山东 济宁
关键词: 汉黄芩素；抗炎；抗肿瘤；神经保护；抗病毒；免疫调节；药理机制；Wogonin； Anti-Inflammatory； Anti-Tumor； Neuroprotective； Antiviral； Immunomodulatory； Pharmacological Mechanisms
摘要: 汉黄芩素(Wogonin)，一种从传统中药黄芩(Scutellaria Baicalensis)中提取的黄酮类化合物，近年来因其多种生物活性而成为药理学研究的热点。其主要药理作用包括抗炎、抗氧化、抗肿瘤、神经保护、抗病毒及免疫调节等。体外和体内研究表明，汉黄芩素能够通过多种分子机制发挥药理作用，并且在多种疾病模型中展现出潜在的治疗效果。本文旨在系统性总结汉黄芩素的药理作用及其机制，为其进一步的药物开发和临床应用提供理论依据。
Abstract: Wogonin, a flavonoid compound extracted from the traditional Chinese medicine Scutellaria baicalensis, has gained attention in pharmacological research in recent years due to its diverse biological activities. Its primary pharmacological effects include anti-inflammatory, antioxidant, antitumor, neuroprotective, antiviral, and immunomodulatory properties. Both in vitro and in vivo studies have shown that wogonin exerts its pharmacological effects through various molecular mechanisms and demonstrates potential therapeutic effects in multiple disease models. This article aims to systematically summarize the pharmacological effects and mechanisms of Wogonin, providing a theoretical basis for its further drug development and clinical applications.
文章引用：李忠鑫, 陈雪英, 甘立军. 汉黄芩素的药理作用综述[J]. 中医学, 2024, 13(11): 3039-3046. https://doi.org/10.12677/tcm.2024.1311448

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