针刺内关穴对围绝经期综合征患者自主神经功能的影响

Effect of Acupuncture at Neiguan Point on Autonomic Nervous Function in Patients with Perimenopausal Syndrome

摘要: 目的：通过针刺围绝经期综合征患者双侧内关穴，记录患者针刺过程中不同时间段的心率变异性时域指标和频域指标的变化，探究针刺内关穴对围绝经期综合征患者自主神经功能的影响。方法：选取黑龙江中医药大学附属第一医院针灸六科收治的60例围绝经期患者，随机分为内关穴组和非经非穴组，每组30例。内关穴组选取双侧内关穴针刺，非经非穴组选取双侧内关穴上1 cm针刺。记录两组针刺前(针刺前10 min)、进针时、行针时(针刺得气后10 mn)、出针时(针刺得气后30 min)、出针后10 min，共5个时间节点的时域指标(SDNN)和频域指标(LF、HF、LF/HF、VLF)的数值，将所有数据录入SPSS26.0软件进行统计学分析。结果：两组针刺各个时间段SDNN、LF、HF、LF/HF、VLF与针刺前比较，差异有统计学意义(P < 0.05)。内关穴组针刺各个时间段SDNN、LF、HF、VLF低于非经非穴组，差异具有统计学意义(P < 0.05)，内关穴组针刺各个时间段LF/HF高于非经非穴组，差异具有统计学意义(P < 0.05)。结论：给予围绝经期综合征患者双侧内关穴针刺，可抑制患者交感神经及迷走神经的活性，使自主神经系统的平衡性得到重新调节，同时还具有一定的针刺遗留效应。

Abstract: Objective: This paper aims to investigate the effect of acupuncture at bilateral Neiguan point on autonomic nervous function in patients with perimenopausal syndrome by recording the changes of heart rate variability in time domain and frequency domain during different periods of acupuncture. Methods: 60 cases of perimenopausal patients admitted to the sixth Department of Acupuncture and moxibustion in the First Affiliated Hospital of Heilongjiang University of Chinese Medicine were randomly divided into Neiguan point group and non-jingfei point group, with 30 cases in each group. In Neiguan group, acupuncture at both Neiguan points was selected, and acupuncture at 1 cm above both Neiguan points was selected for non-meridian and non-meridian points. The time domain indexes (SDNN) and frequency domain indexes (LF, HF, LF/HF, VLF) of the two groups were recorded at 5 time points: before acupuncture (10 min before acupuncture), during needle insertion, during needle line (10 min after acupuncture to obtain gas), during needle extraction (30 min after acupuncture), and 10 min after acupuncture extraction. All data were entered into SPSS26.0 software for statistical analysis. Result: There were significant differences in SDNN, LF, HF, LF/HF, VLF and TP between the two groups before acupuncture (P < 0.05). The SDNN, LF, HF, VLF and TP in Neiguan group were lower than those in non-jingfei group. The difference was statistically significant (P < 0.05). LF/HF in Neiguan acupuncture group was higher than that in non-jingfei acupuncture group at each time period, and the difference was statistically significant (P < 0.05). Conclusion: In patients with perimenopausal syndrome, bilateral Neiguan acupuncture can inhibit the activity of sympathetic nerve and vagus nerve, re-regulate the balance of autonomic nerve, and have some residual effects of acupuncture.