基于“护场”理论探讨中西医结合防治乳腺癌肝转移的思路

Discussion on the Idea of Prevention and Treatment of Breast Cancer Liver Metastasis by Combining Traditional Chinese and Western Medicine Based on the Theory of “Field Protection”

摘要: 乳腺癌发病人数逐年攀升，相较于其他部位转移的患者，乳腺癌肝转移患者通常预后较差。“护场”指正邪交争过程中，正气约束邪气，使之不至于深陷或扩散而形成的局部作肿范围。中医认为，癌毒侵袭转移与护场不守有关。护场的微观基础为免疫微环境，能识别和杀伤癌变细胞，而免疫逃逸在促进肿瘤转移方面发挥重要作用。基于“护场”理论，笔者从中西医结合角度分析乳腺癌肝转移病机，并提出从清除癌毒、固护护场以及先安未受邪之地三个方面进行干预，为中西医结合防治乳腺癌肝转移提供新思路。

Abstract: The incidence of breast cancer is increasing year by year. Compared with patients with other metastatic sites, patients with liver metastasis of breast cancer usually have a worse prognosis. “Field protection” refers to the local swelling range formed by the restraint of positive qi on evil qi in the process of the conflict between good and evil, so that it will not be deep or diffuse. Traditional Chinese medicine believes that the invasion and metastasis of cancer virus are related to the failure to field protection. The microscopic basis of the field protection is the immune microenvironment, which can recognize and kill cancerous cells, and immune escape plays an important role in promoting tumor metastasis. Based on the theory of “field protection”, the author analyzed the pathogenesis of breast cancer liver metastasis from the perspective of integrated traditional Chinese and Western medicine, and proposed three aspects of intervention: removing cancer poison, strengthening the field and protecting the uninfected area first, providing new ideas for the prevention and treatment of breast cancer liver metastasis with integrated traditional Chinese and Western medicine.