多囊卵巢综合征合并年轻型子宫内膜癌二例
Two Cases of Polycystic Ovary Syndrome Combined with Young Endometrial Cancer
DOI: 10.12677/acm.2025.151062, PDF,   
作者: 莫 滟, 帅翰林*：暨南大学附属第一医院妇科，广东 广州；李 平：暨南大学基础医学院，广东 广州
关键词: 多囊卵巢综合征；子宫内膜肿瘤；子宫内膜增生；Polycystic Ovary Syndrome； Endometrial Tumor； Endometrial Hyperplasia
摘要: 子宫内膜癌的发病年龄呈现出日益年轻化的趋势，该病症在临床表现上缺乏特异性，其症状往往与失调性子宫出血高度相似，这使得两者在初步诊断时容易相互混淆。对于患有多囊卵巢综合征的女性而言，如果同时合并子宫内膜癌，漏诊和误诊的风险会进一步增加。本文报道2例多囊卵巢综合征合并年轻子宫内膜癌患者，1例患者行宫腔镜切除病灶并联合孕激素治疗、醋酸甲羟孕酮联合二甲双胍治疗，另1例行腹腔镜下全子宫 + 双侧输卵管切除术，保留了卵巢功能。回顾性分析病例资料并复习相关文献，总结其临床特点、组织病理学表现、诊断、治疗及预后，以期提高临床对年轻型子宫内膜癌的警惕。
Abstract: In recent years, endometrial cancer is becoming younger and younger, and is similar to dysfunctional uterine bleeding due to the lack of specificity in clinical presentation. If endometrial cancer is combined with polycystic ovary syndrome, it is more likely to be underdiagnosed or misdiagnosed. In this paper, we report two cases of polycystic ovary syndrome combined with endometrial cancer in young patients, one patient underwent hysteroscopic resection of the lesion and combined progesterone therapy, medroxyprogesterone acetate combined with metformin therapy, and the another underwent Laparoscopic total uterus + bilateral salpingo-oophorectomy, which preserved the function of the ovaries. We retrospectively analyzed the case data and reviewed the relevant literature to summarize the clinical features, histopathological manifestations, diagnosis, treatment and prognosis in order to increase clinical alertness to young endometrial cancer.
文章引用：莫滟, 帅翰林, 李平. 多囊卵巢综合征合并年轻型子宫内膜癌二例[J]. 临床医学进展, 2025, 15(1): 449-456. https://doi.org/10.12677/acm.2025.151062

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