穴位贴敷联合艾灸治疗胃癌化疗后恶心呕吐的应用研究

Application Research of Acupoint Patch Combined with Moxibustion in Treating Nausea and Vomiting after Gastric Cancer Chemotherapy

摘要: 目的：研究在胃癌化疗后恶心呕吐治疗中采取穴位贴敷联合艾灸方案的有效性。方法：研究对象为柳州市工人医院收治的胃癌化疗后恶心呕吐患者50例，纳入时间2023年1月~2024年10月，实施单双数法，25例纳入对照组：化疗前格拉司琼、地塞米松静脉滴注及口服奥美拉唑；其余25例纳入研究组：在对照组的基础上加以穴位贴敷和艾灸疗法。比较组间恶心呕吐VAS评分、延迟性呕吐、体力状况、生活质量、化疗依从性、不良事件。结果：研究组恶心呕吐VAS评分明显低于比较组；比较组延迟性呕吐发生率高于研究组；研究组治疗体力状况优于比较组；研究组治疗后生活质量和化疗依从性均高于比较组(P < 0.05)。两组患者均未见任何不良事件。结论：在胃癌化疗后恶心呕吐治疗中应用穴位贴敷联合艾灸，可以降低延迟性呕吐发生率，减轻恶心呕吐程度，改善体力状况和生活质量，提高化疗依从性，鲜少发生不良事件。

Abstract: Objective: To investigate the effectiveness of a combined acupoint patch and moxibustion treatment for nausea and vomiting following cancer chemotherapy. Methods: The study subjects were 50 cases of gastric cancer patients with nausea and vomiting after chemotherapy admitted to Liuzhou Workers’ Hospital. They were included from January 2023 to October 2024, using odd-even number method. 25 cases were included in the control group: intravenous infusion of granisetron and dexamethasone and oral omeprazole before chemotherapy. The other 25 cases were included in the study group: on the basis of the control group, acupoint application and moxibustion therapy were applied. The VAS score of nausea and vomiting, delayed vomiting, physical status, quality of life, chemotherapy compliance, and adverse events were compared between groups. Results: The VAS score of nausea and vomiting in the study group was significantly lower than that in the comparison group. The incidence of delayed vomiting in the comparison group was higher than that in the study group. The physical strength of the study group was better than that of the comparison group. The quality of life and chemotherapy compliance of the study group after treatment were higher than those of the comparison group (P < 0.05). No adverse events were observed in either group. Conclusion: The application of acupoint application combined with moxibustion in the treatment of nausea and vomiting after chemotherapy for gastric cancer can reduce the incidence of delayed vomiting, reduce the degree of nausea and vomiting, improve physical condition and quality of life, improve chemotherapy compliance, and rarely cause adverse events.