慢性骨髓炎的国内研究进展

Research Progress in Chronic Osteomyelitis in China

摘要: 目的：对国内外慢性骨髓炎(Chronic osteomyelitis, COM)临床诊断和治疗方法进行综述。方法：查阅有关国内外慢性骨髓炎的文献并且对其临床诊断和治疗方法进行归纳分类，最后进行展望。结果：目前慢性骨髓炎的诊疗已经取得了一定成果，诊断治疗慢性骨髓炎的技术趋于成熟，依托基础科学的发展，出现了多种诊疗技术，主要围绕如何合理应用抗生素、合理清除感染死骨及组织和弥补缺失组织三方面提升诊疗水平。结论：慢性骨髓炎的诊疗仍然需要投入更多的研究以提升普及目前的诊疗水平，减少致病菌感染，在诊断致病菌和感染区域上做到更准确，在治疗恢复上做到疗效更好，复感风险更低。

Abstract: Objective: To review the clinical diagnosis and treatment methods of chronic osteomyelitis (COM) in China. Methods: Literature on chronic osteomyelitis both domestically and internationally was reviewed, and its clinical diagnosis and treatment methods were summarized and classified. Finally, a prospect was made. Results: At present, certain achievements have been made in the diagnosis and treatment of chronic osteomyelitis. The techniques for diagnosing and treating chronic osteomyelitis are becoming more mature. Relying on the development of basic sciences, a variety of diagnostic and therapeutic techniques have emerged, mainly focusing on three aspects to improve the level of diagnosis and treatment: how to use antibiotics reasonably, how to remove infected necrotic bones and tissues properly, and how to compensate for missing tissues. Conclusion: More research is still needed for the diagnosis and treatment of chronic osteomyelitis to popularize the current level of diagnosis and treatment, reduce the infection of pathogenic bacteria, achieve more accurate diagnosis of pathogenic bacteria and infected areas, and ensure better therapeutic effects and lower risks of re-infection in the treatment and recovery process.