益经汤治疗早发性卵巢功能不全的研究进展

Research Progress of the Treatment of Premature Ovarian Insufficiency with Yijing Decoction

摘要: 早发性卵巢功能不全是指女性40岁之前出现的卵巢功能衰退，严重危害女性生育力。随着现代生活方式的转变，该病发病率逐年上升，且有年轻化趋势。益经汤是中医临床常用方剂，古往今来常用于治疗“年未老经水断”，即卵巢早衰。药理学研究表明，益经汤通过多靶点、多层面抑制卵巢炎症反应，激活卵巢细胞生长代谢，改善实验室指标，能有效缓解临床症状、提高卵巢功能。本文从中医和西医角度分别探讨益经汤的作用机制，总结益经汤治疗早发性卵巢功能不全的研究进展。

Abstract: Premature ovarian insufficiency refers to the decline of ovarian function in women before the age of 40, which seriously endangers female fertility. With the transformation of modern lifestyles, the incidence of this disease has been increasing year by year, and there is a trend of younger onset. Yijing Decoction is a commonly used traditional Chinese medicine formula, which has been used for treating “menstruation cessation before old age”, that is, premature ovarian failure, since ancient times. Pharmacological studies have shown that Yijing Decoction can effectively alleviate clinical symptoms and improve ovarian function by inhibiting ovarian inflammatory responses through multiple targets and multiple levels, activating the growth and metabolism of normal ovarian cells, and improving laboratory indicators. This article discusses the mechanism of action of Yijing Decoction from both traditional Chinese medicine and Western medicine perspectives and summarizes the research progress of Yijing Decoction in the treatment of premature ovarian insufficiency.