纳米药物靶向技术在动脉粥样硬化诊治的进展
Advances in Atherosclerosis Diagnosis and Treatment with Nanomedicine Targeting Technology
DOI: 10.12677/acm.2025.152490, PDF,    科研立项经费支持
作者: 刘红利, 李雪霖*:重庆医科大学,重庆;重庆市人民医院健康管理中心,重庆
关键词: 动脉粥样硬化纳米粒主动靶向Atherosclerosis Nanoparticles Active Targeting
摘要: 动脉粥样硬化是心血管疾病发生发展的重要病理基础之一,主要包括泡沫细胞形成,坏死核心,血栓形成或斑块破裂。随着纳米药物递送技术在肿瘤医学研究的应用,纳米载体给药系统在心血管疾病中也备受关注。根据纳米药物递送系统在动脉粥样硬化中靶向斑块、斑块局部释放药物和提高斑块内药物有效浓度等方面的特点,我们系统介绍了相关靶向药物在动脉粥样硬化诊疗的应用,为纳米药物递送系统在动脉粥样硬化的诊疗进一步研究提供了参考。
Abstract: Atherosclerosis is one of the important pathologic bases for the development of cardiovascular disease, which mainly includes foam cell formation, necrotic core, thrombosis or plaque rupture. With the application of nanomedicine delivery technology in medical oncology research, nanocarrier drug delivery systems in cardiovascular diseases have also attracted much attention. According to the characteristics of nano drug delivery systems in atherosclerosis in terms of targeting plaques, releasing drugs locally in plaques and increasing the effective concentration of drugs in plaques, we systematically introduce the application of relevant targeted drugs in the diagnosis and treatment of atherosclerosis, which provides a reference for the further research on the diagnosis and treatment of atherosclerosis by nanocarrier drug delivery systems.
文章引用:刘红利, 李雪霖. 纳米药物靶向技术在动脉粥样硬化诊治的进展[J]. 临床医学进展, 2025, 15(2): 1409-1416. https://doi.org/10.12677/acm.2025.152490

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