水产品中喹诺酮类药物检测方法研究进展
Research Progress on Detection Methods of Quinolone Drugs in Aquatic Products
DOI: 10.12677/ojfr.2025.121004, PDF,   
作者: 赖长胜, 刘天密*, 林 毅, 王安伟：海南省水产品质量安全检测中心，海南 海口
关键词: 水产品；喹诺酮；检测方法；Aquatic Products； Quinolone； Test Method
摘要: 喹诺酮类药物作为一种具备高效良好性的抗菌灭毒药物，在具备抗病毒和抗真菌的作用的同时，还具有很好的利用度和耐受性，在水产养殖病害防治领域中广泛使用。随着应用越来越普遍，喹诺酮的耐药性、药物残留问题屡见不鲜，给水产养殖业的发展及人类的生活都带来了极大的危害。本文将现有关于喹诺酮类药物残留的检测技术及研究进展做一简单综述和分析，希望能为今后的水产品安全检测工作提供一些帮助和思考。
Abstract: Quinolones, as highly efficient and effective antibacterial and antiviral drugs, not only have antiviral and antifungal effects, but also have affordable properties with good utilization and tolerance. They are widely used in the field of aquaculture disease prevention and control. With the increasing popularity of quinolone applications, the problems of quinolone resistance and drug residue are not uncommon, which have brought great harm to the development of aquaculture and human life. This article provides a brief review and analysis of the existing detection techniques and research progress on quinolone drug residues, hoping to provide some help and reflection for future aquatic product safety testing work.
文章引用：赖长胜, 刘天密, 林毅, 王安伟. 水产品中喹诺酮类药物检测方法研究进展[J]. 水产研究, 2025, 12(1): 29-32. https://doi.org/10.12677/ojfr.2025.121004

参考文献

[1] Huan, L.L., Mo, Y.M., Wu, Z.Q., et al. (2020) Occurrence, Distribution, and Health Risk Assessment of Quinolone Antibiotics in Water, Sediment, and Fish Species of Qingshitan Reservoir, South China. Scientific Reports, 10, Article No. 15777.
[2] He, X., Deng, M., Wang, Q., Yang, Y., Yang, Y. and Nie, X. (2016) Residues and Health Risk Assessment of Quinolones and Sulfonamides in Cultured Fish from Pearl River Delta, China. Aquaculture, 458, 38-46. [Google Scholar] [CrossRef] 
[3] Jin, Y., Zhang, W.Y., Wang, Q., Yang, Y.Q., Liang, L.Y. and Yan, S.J. (2014) Determination of Fluoroquinolones Residual in Freshwater Fish by Hplc. Advanced Materials Research, 1033, 634-637. [Google Scholar] [CrossRef] 
[4] (2006) FDA: More Efficient Drug Review. Emergency Medicine News, 28, 32. [Google Scholar] [CrossRef] 
[5] 高志存, 石露莎, 余舒宁, 等. 动物源性食品中8种氟喹诺酮类药物多残留高效液相色谱检测方法的建立[J]. 中国动物检疫, 2023, 40(7): 116-120.
[6] 黄晓蓉, 郑晶, 李寿崧, 等. 鳗鱼及其制品中喹诺酮类药物残留的微生物快速检测方法研究[J]. 淡水渔业, 2005, 35(4): 3-6.
[7] 童文羽, 朱志强, 曾智. 高效液相色谱法检测水产品中三种喹诺酮类药物残留量方法研究[J]. 渔业致富指南, 2018(16): 59-64.
[8] 张莉, 吴莉, 李爽, 等. 改良QuEChERS-超高效液相色谱-串联质谱同时检测淡水鱼中11种喹诺酮类抗生素残留[J]. 河南预防医学杂志，2022, 33(10): 757-760, 780.
[9] 叶玫, 吴成业, 刘海新, 等. 酶联免疫吸附法在水产品安全检测中的应用[J]. 上海水产大学学报, 2002, 11(2): 171-175.
[10] 郑百芹, 罗晓琴, 冯才伟, 等. 一种喹诺酮类药物的酶联免疫快速检测试剂盒的研制[J]. 中国酿造, 2014, 33(2): 130-133.
[11] Petersen, J.R., Okorodudu, A.O., Mohammad, A. and Payne, D.A. (2003) Capillary Electrophoresis and Its Application in the Clinical Laboratory. Clinica Chimica Acta, 330, 1-30. [Google Scholar] [CrossRef] [PubMed]
[12] 陈义. 毛细管电泳技术及应用[M]. 北京: 化学工业出版社, 2006.
[13] 陈宗保, 王星, 尹月春, 等. 改性纳米金富集-毛细管电泳电化学发光法测定水产品中4种氟喹诺酮类药物残留[J]. 分析测试学报, 2019, 38(2): 176-181.

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