玻璃酸钠滴眼液及小牛血去蛋白提取物眼用凝胶在角膜异物剔除术后的应用

Application of Sodium Hyaluronate Eye Drops and Deproteinized Calf Blood Extract Eye Gel after the Corneal Foreign Body Removal

摘要: 目的：比较玻璃酸钠滴眼液联合左氧氟沙星滴眼液以及小牛血去蛋白提取物眼用凝胶联合左氧氟沙星滴眼液对角膜异物剔除术后的临床疗效。方法：选取2024年6月至2024年12月在我院行角膜异物剔除术的患者159例，随机分为玻璃酸钠滴眼液组80例和小牛血去蛋白提取物眼用凝胶组79例。两组分别给予玻璃酸钠滴眼液联合左氧氟沙星滴眼液治疗和小牛血去蛋白提取物眼用凝胶联合左氧氟沙星滴眼液治疗，比较两组患者的术后恢复情况。结果：玻璃酸钠滴眼液组80例中痊愈63例，好转17例，无效0例，痊愈率78.8%，有效率100%；小牛血去蛋白提取物眼用凝胶组79例中痊愈70例，好转9例，无效0例，痊愈率86.1%，有效率100%，两组痊愈率比较，差异有统计学意义(P < 0.05)。结论：玻璃酸钠滴眼液和小牛血去蛋白提取物眼用凝胶与左氧氟沙星滴眼液联合使用，对角膜异物剔除术后的眼部恢复均有效，其中使用小牛血去蛋白提取物眼用凝胶效果更佳，痊愈率更高。

Abstract: Purpose: To compare the clinical effects of sodium hyaluronate eye drops combined with levofloxacin eye drops and deproteinized calf blood extract eye gel combined with levofloxacin eye drops after corneal foreign body removal. Methods: One hundred and fifty-nine patients who underwent corneal foreign body removal in our hospital from June 2024 to December 2024 were randomly divided into 2 groups: 80 cases in the sodium hyaluronate eye drops group and 79 cases in the deproteinized calf blood extract eye gel group. One group was treated with sodium hyaluronate eye drops combined with levofloxacin eye drops, while another group was treated with deproteinized calf blood extract eye gel combined with levofloxacin eye drops. The postoperative recoveries of the patients in the two groups were compared. Results: 63 cases of 80 cases in the sodium hyaluronate eye drops group were cured, 17 cases got better, 0 cases were invalid, the recovery rate was 78.8%, and the effective rate was 100%; 70 cases of 79 cases in the deproteinized calf blood extract eye gel group were cured, 9 cases got better, 0 cases were invalid, the recovery rate was 86.1%, and the effective rate was 100%, the difference between the two groups’ recovery rates was statistically significant (P < 0.05). Conclusion: Sodium hyaluronate eye drops and deproteinized calf blood extract eye gel, when used in combination with levofloxacin eye drops, are effective in the recovery of the eye after corneal foreign body removal, in which the use of deproteinized calf blood extract eye gel is more effective, with a higher rate of healing.