氟西汀联合团体辩证行为疗法治疗伴有非自杀性自伤的青少年抑郁障碍患者

Fluoxetine Combined with Group Dialectical Behavior Therapy for the Treatment of Adolescents with Non-Suicidal Self-Injury and Depressive Disorders

摘要: 目的：了解团体辩证行为疗法(dialectical behavior therapy, DBT)治疗伴有非自杀性自伤(non-suicidal self-injury, NSSI)行为的青少年抑郁障碍患者的临床疗效。方法：选择40名伴有NSSI的青少年抑郁障碍患者为研究对象，分为对照组和实验组，对照组应用氟西汀治疗，实验组应用氟西汀联合团体DBT治疗。比较两组患者治疗前、治疗4周后、治疗8周后的汉密尔顿抑郁量表(Hamilton depression scale, HAMD)、认知情绪调节量表(cognitive emotion regulation questionnaire, CERQ)、自我伤害想法和行为访谈表(self-injurious thoughts and behaviors interview, SITBI)的变化。结果：实验组比对照组在认知情绪调节和NSSI方面有更显著的改善(P < 0.05)。结论：团体DBT能够改变伴有NSSI的青少年抑郁障碍患者的认知情绪调节策略，有效减少其NSSI行为及想法的发生。

Abstract: Objective: To study the clinical efficacy of group dialectical behavior therapy (DBT) in treating adolescent patients with depressive disorders accompanied by non-suicidal self-injury (NSSI). Methods: A total of 40 adolescent patients with depressive disorders accompanied by NSSI were selected as the subjects of the study, divided into a control group and an experimental group. The control group was treated with fluoxetine, while the experimental group received a combination of fluoxetine and group DBT. The changes in the Hamilton depression scale (HAMD), cognitive emotion regulation questionnaire (CERQ), and self-injurious thoughts and behaviors interview (SITBI) before treatment, after 4 weeks of treatment, and after 8 weeks of treatment were compared between the two groups. Results: The experimental group showed more significant improvements in cognitive emotion regulation and NSSI than the control group (P < 0.05). Conclusion: Group DBT can change the cognitive emotion regulation strategies of adolescent patients with depressive disorders accompanied by NSSI, effectively reducing the occurrence of NSSI behaviors and thoughts.