高压氧联合西医基础治疗单纯性肠梗阻临床效果及对患者胃肠功能的影响

Clinical Effect of Hyperbaric Oxygen Combined with Western Medicine in Basic Treatment of Simple Intestinal Obstruction and Its Influence on Gastrointestinal Function

摘要: 目的：探讨单纯性肠梗阻患者行高压氧联合西医基础治疗后的临床效果及其对患者胃肠功能的影响，为临床治疗提供相关参考依据。方法：本研究采用便利抽样法选取2024年1月至2025年3月在吴起县人民医院普外科住院治疗的单纯性肠梗阻患者，作为研究研究对象。根据患者病情需要与治疗方案，按照就诊奇偶数次序，将单纯性肠梗阻患者分为两组，奇数为对照组，偶数为观察者，严格按照医嘱治疗7天后，评估相关指标。本研究采用SPSS 26.0软件统计分析，计数资料组间比较采用c²检验；计量资料组间比较采用t检验或非参数检验；以P < 0.05为差异具有统计学意义。结果：本研究共纳入64例单纯性肠梗阻患者，对照组32例、观察组32例，两组患者在不同人口学资料和疾病相关资料上的差异性分析无统计学意义(P > 0.05)，两组患者具有可比性。对照组患者在治疗过程中由于病情发展转手术治疗2例，后期对照组观察对象为30例。观察组患者在肠鸣音恢复时间、首次肛门排便时间、腹胀、腹痛症状明显缓解时间上显著少于对照组患者，差异具有统计学意义(P < 0.05)，但是两组患者在住院时间、首次肛门排气时间上无显著差异(P > 0.05)。观察组患者临床治疗方案疗效(治愈率为84.4%)优于对照组(治愈率为56.3%)，差异具有统计学意义(P < 0.05)，两组治疗方案并发症总发生率无明显差异(P > 0.05)。结论：高压氧联合西医基础治疗可以明显促进单纯性肠梗阻患者胃肠功能恢复，其疗效安全可行。

Abstract: Objective: To investigate the clinical effect of hyperbaric oxygen combined with Western medicine basic treatment for patients with simple intestinal obstruction and its influence on gastrointestinal function, and to provide relevant reference for clinical treatment. Methods: In this study, patients with simple ileus who were hospitalized in the Department of General Surgery of Wuqi County People’s Hospital from January 2024 to March 2025 were selected by convenience sampling method as research objects. According to patients’ needs and treatment plan, patients with simple ileus were divided into two groups according to the odd and even order of visits, with an odd number as the control group and an even number as the observer. After 7 days of strict treatment according to the doctor’s advice, the relevant indicators were evaluated. In this study, SPSS 26.0 software was used for statistical analysis, and comparison among data groups was conducted by c² test. t test or non-parametric test was used for comparison between measurement data groups. P < 0.05 was considered to be statistically significant. Results: A total of 64 patients with simple ileus were included in this study, 32 in the control group and 32 in the observation group. There was no statistical significance in the analysis of different demographic data and disease-related data between the two groups (P > 0.05), indicating that patients in the two groups were comparable. In the control group, 2 patients were transferred to surgery due to the development of the disease during treatment, and 30 patients were observed in the later period of the control group. The recovery time of bowel sound, first anal defecation, abdominal distension and abdominal pain in observation group were significantly less than those in control group, with statistical significance (P < 0.05), but there was no significant difference between the two groups in hospital stay and first anal exhaust time (P > 0.05). The curative effect of the treatment regimen in the observation group (cure rate was 84.4%) was better than that in the control group (cure rate was 56.3%), the difference was statistically significant (P < 0.05), and the total complication rate of the treatment regimen was not significantly different between the two groups (P > 0.05). Conclusion: Hyperbaric oxygen combined with Western basic treatment can obviously promote the recovery of gastrointestinal function in patients with simple intestinal obstruction, and its curative effect is safe and feasible.