早发性卵巢功能不全的生物学治疗研究进展
Advances of Biological Therapies in Premature Ovarian Insufficiency
摘要: 早发性卵巢功能不全(premature ovarian insufficiency, POI)指育龄期女性过早出现卵巢功能衰退,可严重影响患者生活质量及生育能力,且其发病率呈逐年上升的趋势。目前以激素替代治疗为主的传统治疗方式在一定程度可以改善患者症状,但对于生育力的提高有限。在过去数十年中逐步开展了生物学疗法,因其生物成分的修复及再生能力而成为恢复生育力较为有前景的治疗方式。本文将就生物学治疗对卵巢功能的改善的研究进展进行综述。
Abstract: Premature ovarian insufficiency (POI) is a condition in which ovarian function declines prematurely in women of childbearing age. It has seriously affected patients’ quality of life and fertility, and its incidence is increasing year by year. Currently, hormone replacement therapy (HRT) is the primary conventional treatment, offering symptomatic relief but with limited efficacy in improving fertility outcomes. Over the past decades, the development of biological therapies has shown increasing promise for restoring fertility, due to the repairing and regenerating ability of their biological components. This article reviews the advancements in research on the role of biological therapies in improving ovarian function.
文章引用:赵铭, 吴瑞瑾. 早发性卵巢功能不全的生物学治疗研究进展[J]. 临床医学进展, 2025, 15(4): 2325-2333. https://doi.org/10.12677/acm.2025.1541185

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