从中医肝脾肾论治肝硬化的研究进展

Research Progress on the Treatment of Liver Cirrhosis from the Perspective of Liver, Spleen and Kidney in Traditional Chinese Medicine

摘要: 本文基于中医理论系统探讨了肝硬化(Liver Cirrhosis, LC)与肝、脾、肾三脏的生理病理联系及其临床治疗策略。通过分析肝硬化的病机，本研究揭示肝硬化本质为肝络瘀痹、脾虚水停、肾虚精亏的复合病机。文章综述了从肝、脾、肾三脏论治肝硬化的治则治法，强调“益肾填精、健脾利水、调肝化瘀”的综合治疗原则，并结合现代临床研究数据，验证了中医药治疗在改善肝功能、延缓纤维化及提高患者生存质量方面有显著疗效。本研究凸显了中医药“整体观”与“辨证论治”的优势，为肝硬化临床诊疗提供了理论依据与实践参考。

Abstract: Based on traditional Chinese medicine (TCM) theory, this paper systematically explores the physiological and pathological connections between liver cirrhosis (LC) and the liver, spleen, and kidney, as well as the clinical treatment strategies. By analyzing the pathogenesis of liver cirrhosis, it is pointed out that its essence is a composite pathological process of liver collateral obstruction, spleen deficiency with water retention, and kidney deficiency with essence depletion. This article reviews the principles and methods of treating liver cirrhosis from the perspectives of the liver, spleen, and kidney, emphasizing the comprehensive treatment principle of “tonifying kidney and replenishing essence, invigorating the spleen to promote diuresis, and regulating the liver to remove blood stasis”. Combined with modern clinical research data, it verifies the remarkable curative effects of traditional Chinese medicine treatment in improving liver function, delaying fibrosis, and enhancing the quality of life of patients. This study highlights the advantages of the “holistic concept” and “treatment based on syndrome differentiation” in traditional Chinese medicine, providing a theoretical basis and practical reference for the clinical diagnosis and treatment of liver cirrhosis.